Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)

Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging metho...
Ausführliche Beschreibung

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Autor*in:	Guerra, Adalgisa [verfasserIn] Flor-de-Lima, Beatriz Freire, Gonçalo Lopes, Ana Cassis, João

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Prostate Prostatic cancer Extracapsular extension Magnetic resonance imaging Radiologic-pathologic correlation

Anmerkung:	© The Author(s) 2023

Übergeordnetes Werk:	Enthalten in: Insights into imaging - Berlin : Springer, 2010, 14(2023), 1 vom: 16. Mai
Übergeordnetes Werk:	volume:14 ; year:2023 ; number:1 ; day:16 ; month:05

Links:	Volltext

DOI / URN:	10.1186/s13244-023-01428-3

Katalog-ID:	SPR052458458

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520			\|a Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract
520			\|a Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging.
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allfields	10.1186/s13244-023-01428-3 doi (DE-627)SPR052458458 (SPR)s13244-023-01428-3-e DE-627 ger DE-627 rakwb eng Guerra, Adalgisa verfasserin (orcid)0000-0002-0095-5662 aut Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging. Prostate (dpeaa)DE-He213 Prostatic cancer (dpeaa)DE-He213 Extracapsular extension (dpeaa)DE-He213 Magnetic resonance imaging (dpeaa)DE-He213 Radiologic-pathologic correlation (dpeaa)DE-He213 Flor-de-Lima, Beatriz aut Freire, Gonçalo aut Lopes, Ana aut Cassis, João aut Enthalten in Insights into imaging Berlin : Springer, 2010 14(2023), 1 vom: 16. Mai (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:14 year:2023 number:1 day:16 month:05 https://dx.doi.org/10.1186/s13244-023-01428-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2023 1 16 05
spelling	10.1186/s13244-023-01428-3 doi (DE-627)SPR052458458 (SPR)s13244-023-01428-3-e DE-627 ger DE-627 rakwb eng Guerra, Adalgisa verfasserin (orcid)0000-0002-0095-5662 aut Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging. Prostate (dpeaa)DE-He213 Prostatic cancer (dpeaa)DE-He213 Extracapsular extension (dpeaa)DE-He213 Magnetic resonance imaging (dpeaa)DE-He213 Radiologic-pathologic correlation (dpeaa)DE-He213 Flor-de-Lima, Beatriz aut Freire, Gonçalo aut Lopes, Ana aut Cassis, João aut Enthalten in Insights into imaging Berlin : Springer, 2010 14(2023), 1 vom: 16. Mai (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:14 year:2023 number:1 day:16 month:05 https://dx.doi.org/10.1186/s13244-023-01428-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2023 1 16 05
allfields_unstemmed	10.1186/s13244-023-01428-3 doi (DE-627)SPR052458458 (SPR)s13244-023-01428-3-e DE-627 ger DE-627 rakwb eng Guerra, Adalgisa verfasserin (orcid)0000-0002-0095-5662 aut Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging. Prostate (dpeaa)DE-He213 Prostatic cancer (dpeaa)DE-He213 Extracapsular extension (dpeaa)DE-He213 Magnetic resonance imaging (dpeaa)DE-He213 Radiologic-pathologic correlation (dpeaa)DE-He213 Flor-de-Lima, Beatriz aut Freire, Gonçalo aut Lopes, Ana aut Cassis, João aut Enthalten in Insights into imaging Berlin : Springer, 2010 14(2023), 1 vom: 16. Mai (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:14 year:2023 number:1 day:16 month:05 https://dx.doi.org/10.1186/s13244-023-01428-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2023 1 16 05
allfieldsGer	10.1186/s13244-023-01428-3 doi (DE-627)SPR052458458 (SPR)s13244-023-01428-3-e DE-627 ger DE-627 rakwb eng Guerra, Adalgisa verfasserin (orcid)0000-0002-0095-5662 aut Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging. Prostate (dpeaa)DE-He213 Prostatic cancer (dpeaa)DE-He213 Extracapsular extension (dpeaa)DE-He213 Magnetic resonance imaging (dpeaa)DE-He213 Radiologic-pathologic correlation (dpeaa)DE-He213 Flor-de-Lima, Beatriz aut Freire, Gonçalo aut Lopes, Ana aut Cassis, João aut Enthalten in Insights into imaging Berlin : Springer, 2010 14(2023), 1 vom: 16. Mai (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:14 year:2023 number:1 day:16 month:05 https://dx.doi.org/10.1186/s13244-023-01428-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2023 1 16 05
allfieldsSound	10.1186/s13244-023-01428-3 doi (DE-627)SPR052458458 (SPR)s13244-023-01428-3-e DE-627 ger DE-627 rakwb eng Guerra, Adalgisa verfasserin (orcid)0000-0002-0095-5662 aut Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging. Prostate (dpeaa)DE-He213 Prostatic cancer (dpeaa)DE-He213 Extracapsular extension (dpeaa)DE-He213 Magnetic resonance imaging (dpeaa)DE-He213 Radiologic-pathologic correlation (dpeaa)DE-He213 Flor-de-Lima, Beatriz aut Freire, Gonçalo aut Lopes, Ana aut Cassis, João aut Enthalten in Insights into imaging Berlin : Springer, 2010 14(2023), 1 vom: 16. Mai (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:14 year:2023 number:1 day:16 month:05 https://dx.doi.org/10.1186/s13244-023-01428-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2023 1 16 05
language	English
source	Enthalten in Insights into imaging 14(2023), 1 vom: 16. Mai volume:14 year:2023 number:1 day:16 month:05
sourceStr	Enthalten in Insights into imaging 14(2023), 1 vom: 16. Mai volume:14 year:2023 number:1 day:16 month:05
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Prostate Prostatic cancer Extracapsular extension Magnetic resonance imaging Radiologic-pathologic correlation
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container_title	Insights into imaging
authorswithroles_txt_mv	Guerra, Adalgisa @@aut@@ Flor-de-Lima, Beatriz @@aut@@ Freire, Gonçalo @@aut@@ Lopes, Ana @@aut@@ Cassis, João @@aut@@
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author	Guerra, Adalgisa
spellingShingle	Guerra, Adalgisa misc Prostate misc Prostatic cancer misc Extracapsular extension misc Magnetic resonance imaging misc Radiologic-pathologic correlation Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)
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topic_title	Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE) Prostate (dpeaa)DE-He213 Prostatic cancer (dpeaa)DE-He213 Extracapsular extension (dpeaa)DE-He213 Magnetic resonance imaging (dpeaa)DE-He213 Radiologic-pathologic correlation (dpeaa)DE-He213
topic	misc Prostate misc Prostatic cancer misc Extracapsular extension misc Magnetic resonance imaging misc Radiologic-pathologic correlation
topic_unstemmed	misc Prostate misc Prostatic cancer misc Extracapsular extension misc Magnetic resonance imaging misc Radiologic-pathologic correlation
topic_browse	misc Prostate misc Prostatic cancer misc Extracapsular extension misc Magnetic resonance imaging misc Radiologic-pathologic correlation
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title	Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)
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title_full	Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)
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author_browse	Guerra, Adalgisa Flor-de-Lima, Beatriz Freire, Gonçalo Lopes, Ana Cassis, João
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title_sort	radiologic-pathologic correlation of prostatic cancer extracapsular extension (ece)
title_auth	Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)
abstract	Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging. © The Author(s) 2023
abstractGer	Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging. © The Author(s) 2023
abstract_unstemmed	Abstract Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens. Graphical abstract Critical relevance statement MRI can visualize early and late signs of extracapsular extension (ECE), with the early signs being less reproducible between readers, while the presence of ECE measurable on MRI is highly correlated with its presence on pathology. Key points Detection of extracapsular extension (ECE) is important for the preoperative planning of patients with prostate cancer (PCa).The gold standard of PCa local staging is pathology.There is a good Rad/Path correlation of prostate anatomy and PCa findings.The MRI is the best imaging method for PCa staging. © The Author(s) 2023
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title_short	Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)
url	https://dx.doi.org/10.1186/s13244-023-01428-3
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author2	Flor-de-Lima, Beatriz Freire, Gonçalo Lopes, Ana Cassis, João
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Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)

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