Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer
Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Facto...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Nadal, Ernest [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Schlagwörter: |
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| Anmerkung: |
© The Author(s) 2023 |
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| Übergeordnetes Werk: |
Enthalten in: Revista de oncología - Barcelona : Doyma, 2000, 25(2023), 11 vom: 11. Aug., Seite 3139-3151 |
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| Übergeordnetes Werk: |
volume:25 ; year:2023 ; number:11 ; day:11 ; month:08 ; pages:3139-3151 |
| Links: |
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| DOI / URN: |
10.1007/s12094-023-03286-3 |
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SPR053150996 |
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| 520 | |a Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. | ||
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10.1007/s12094-023-03286-3 doi (DE-627)SPR053150996 (SPR)s12094-023-03286-3-e DE-627 ger DE-627 rakwb eng Nadal, Ernest verfasserin aut Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. Lung cancer (dpeaa)DE-He213 mutation (dpeaa)DE-He213 Older adult patient (dpeaa)DE-He213 Targeted therapy (dpeaa)DE-He213 TKI (dpeaa)DE-He213 Geriatric assessment (dpeaa)DE-He213 Oré-Arce, Martín aut Remon, Jordi aut Bernabé-Caro, Reyes aut Covela-Rúa, Marta aut de Castro-Carpeño, Javier aut Massutí-Sureda, Bartomeu aut Guillot-Morales, Mónica aut Majem, Margarita aut Maestu-Maiques, Inmaculada aut Morilla-Ruíz, Idoia aut Gironés, Regina (orcid)0000-0002-5548-0553 aut Enthalten in Revista de oncología Barcelona : Doyma, 2000 25(2023), 11 vom: 11. Aug., Seite 3139-3151 (DE-627)385985452 (DE-600)2143451-7 1578-195X nnns volume:25 year:2023 number:11 day:11 month:08 pages:3139-3151 https://dx.doi.org/10.1007/s12094-023-03286-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 25 2023 11 11 08 3139-3151 |
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10.1007/s12094-023-03286-3 doi (DE-627)SPR053150996 (SPR)s12094-023-03286-3-e DE-627 ger DE-627 rakwb eng Nadal, Ernest verfasserin aut Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. Lung cancer (dpeaa)DE-He213 mutation (dpeaa)DE-He213 Older adult patient (dpeaa)DE-He213 Targeted therapy (dpeaa)DE-He213 TKI (dpeaa)DE-He213 Geriatric assessment (dpeaa)DE-He213 Oré-Arce, Martín aut Remon, Jordi aut Bernabé-Caro, Reyes aut Covela-Rúa, Marta aut de Castro-Carpeño, Javier aut Massutí-Sureda, Bartomeu aut Guillot-Morales, Mónica aut Majem, Margarita aut Maestu-Maiques, Inmaculada aut Morilla-Ruíz, Idoia aut Gironés, Regina (orcid)0000-0002-5548-0553 aut Enthalten in Revista de oncología Barcelona : Doyma, 2000 25(2023), 11 vom: 11. Aug., Seite 3139-3151 (DE-627)385985452 (DE-600)2143451-7 1578-195X nnns volume:25 year:2023 number:11 day:11 month:08 pages:3139-3151 https://dx.doi.org/10.1007/s12094-023-03286-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 25 2023 11 11 08 3139-3151 |
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10.1007/s12094-023-03286-3 doi (DE-627)SPR053150996 (SPR)s12094-023-03286-3-e DE-627 ger DE-627 rakwb eng Nadal, Ernest verfasserin aut Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. Lung cancer (dpeaa)DE-He213 mutation (dpeaa)DE-He213 Older adult patient (dpeaa)DE-He213 Targeted therapy (dpeaa)DE-He213 TKI (dpeaa)DE-He213 Geriatric assessment (dpeaa)DE-He213 Oré-Arce, Martín aut Remon, Jordi aut Bernabé-Caro, Reyes aut Covela-Rúa, Marta aut de Castro-Carpeño, Javier aut Massutí-Sureda, Bartomeu aut Guillot-Morales, Mónica aut Majem, Margarita aut Maestu-Maiques, Inmaculada aut Morilla-Ruíz, Idoia aut Gironés, Regina (orcid)0000-0002-5548-0553 aut Enthalten in Revista de oncología Barcelona : Doyma, 2000 25(2023), 11 vom: 11. Aug., Seite 3139-3151 (DE-627)385985452 (DE-600)2143451-7 1578-195X nnns volume:25 year:2023 number:11 day:11 month:08 pages:3139-3151 https://dx.doi.org/10.1007/s12094-023-03286-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 25 2023 11 11 08 3139-3151 |
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10.1007/s12094-023-03286-3 doi (DE-627)SPR053150996 (SPR)s12094-023-03286-3-e DE-627 ger DE-627 rakwb eng Nadal, Ernest verfasserin aut Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. Lung cancer (dpeaa)DE-He213 mutation (dpeaa)DE-He213 Older adult patient (dpeaa)DE-He213 Targeted therapy (dpeaa)DE-He213 TKI (dpeaa)DE-He213 Geriatric assessment (dpeaa)DE-He213 Oré-Arce, Martín aut Remon, Jordi aut Bernabé-Caro, Reyes aut Covela-Rúa, Marta aut de Castro-Carpeño, Javier aut Massutí-Sureda, Bartomeu aut Guillot-Morales, Mónica aut Majem, Margarita aut Maestu-Maiques, Inmaculada aut Morilla-Ruíz, Idoia aut Gironés, Regina (orcid)0000-0002-5548-0553 aut Enthalten in Revista de oncología Barcelona : Doyma, 2000 25(2023), 11 vom: 11. Aug., Seite 3139-3151 (DE-627)385985452 (DE-600)2143451-7 1578-195X nnns volume:25 year:2023 number:11 day:11 month:08 pages:3139-3151 https://dx.doi.org/10.1007/s12094-023-03286-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 25 2023 11 11 08 3139-3151 |
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10.1007/s12094-023-03286-3 doi (DE-627)SPR053150996 (SPR)s12094-023-03286-3-e DE-627 ger DE-627 rakwb eng Nadal, Ernest verfasserin aut Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. Lung cancer (dpeaa)DE-He213 mutation (dpeaa)DE-He213 Older adult patient (dpeaa)DE-He213 Targeted therapy (dpeaa)DE-He213 TKI (dpeaa)DE-He213 Geriatric assessment (dpeaa)DE-He213 Oré-Arce, Martín aut Remon, Jordi aut Bernabé-Caro, Reyes aut Covela-Rúa, Marta aut de Castro-Carpeño, Javier aut Massutí-Sureda, Bartomeu aut Guillot-Morales, Mónica aut Majem, Margarita aut Maestu-Maiques, Inmaculada aut Morilla-Ruíz, Idoia aut Gironés, Regina (orcid)0000-0002-5548-0553 aut Enthalten in Revista de oncología Barcelona : Doyma, 2000 25(2023), 11 vom: 11. Aug., Seite 3139-3151 (DE-627)385985452 (DE-600)2143451-7 1578-195X nnns volume:25 year:2023 number:11 day:11 month:08 pages:3139-3151 https://dx.doi.org/10.1007/s12094-023-03286-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 25 2023 11 11 08 3139-3151 |
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Enthalten in Revista de oncología 25(2023), 11 vom: 11. Aug., Seite 3139-3151 volume:25 year:2023 number:11 day:11 month:08 pages:3139-3151 |
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Nadal, Ernest @@aut@@ Oré-Arce, Martín @@aut@@ Remon, Jordi @@aut@@ Bernabé-Caro, Reyes @@aut@@ Covela-Rúa, Marta @@aut@@ de Castro-Carpeño, Javier @@aut@@ Massutí-Sureda, Bartomeu @@aut@@ Guillot-Morales, Mónica @@aut@@ Majem, Margarita @@aut@@ Maestu-Maiques, Inmaculada @@aut@@ Morilla-Ruíz, Idoia @@aut@@ Gironés, Regina @@aut@@ |
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Nadal, Ernest Oré-Arce, Martín Remon, Jordi Bernabé-Caro, Reyes Covela-Rúa, Marta de Castro-Carpeño, Javier Massutí-Sureda, Bartomeu Guillot-Morales, Mónica Majem, Margarita Maestu-Maiques, Inmaculada Morilla-Ruíz, Idoia Gironés, Regina |
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Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer |
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Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. © The Author(s) 2023 |
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Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. © The Author(s) 2023 |
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Abstract Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. © The Author(s) 2023 |
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Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer |
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