Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX)

Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylat...
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Autor*in:	Bardajee, Ghasem Rezanejade [verfasserIn] Jafari, Roghayeh

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Nanogel synthesis Interpenetrating networks nanogels Drug release Alginate biopolymer

Anmerkung:	© The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Übergeordnetes Werk:	Enthalten in: Journal of polymer research - Dordrecht : Springer Science + Business Media B.V., 1994, 30(2023), 10 vom: 29. Sept.
Übergeordnetes Werk:	volume:30 ; year:2023 ; number:10 ; day:29 ; month:09

Links:	Volltext

DOI / URN:	10.1007/s10965-023-03769-5

Katalog-ID:	SPR053234324

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520			\|a Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied.
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912			\|a GBV_ILN_110
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912			\|a GBV_ILN_138
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_152
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_171
912			\|a GBV_ILN_187
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
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912			\|a GBV_ILN_250
912			\|a GBV_ILN_281
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_636
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
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912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2037
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2039
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2057
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2093
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2107
912			\|a GBV_ILN_2108
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2119
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912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2144
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912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
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912			\|a GBV_ILN_4242
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allfields	10.1007/s10965-023-03769-5 doi (DE-627)SPR053234324 (SPR)s10965-023-03769-5-e DE-627 ger DE-627 rakwb eng Bardajee, Ghasem Rezanejade verfasserin (orcid)0000-0001-7331-0059 aut Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied. Nanogel synthesis (dpeaa)DE-He213 Interpenetrating networks nanogels (dpeaa)DE-He213 Drug release (dpeaa)DE-He213 Alginate biopolymer (dpeaa)DE-He213 Jafari, Roghayeh aut Enthalten in Journal of polymer research Dordrecht : Springer Science + Business Media B.V., 1994 30(2023), 10 vom: 29. Sept. (DE-627)340872098 (DE-600)2065616-6 1572-8935 nnns volume:30 year:2023 number:10 day:29 month:09 https://dx.doi.org/10.1007/s10965-023-03769-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2023 10 29 09
spelling	10.1007/s10965-023-03769-5 doi (DE-627)SPR053234324 (SPR)s10965-023-03769-5-e DE-627 ger DE-627 rakwb eng Bardajee, Ghasem Rezanejade verfasserin (orcid)0000-0001-7331-0059 aut Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied. Nanogel synthesis (dpeaa)DE-He213 Interpenetrating networks nanogels (dpeaa)DE-He213 Drug release (dpeaa)DE-He213 Alginate biopolymer (dpeaa)DE-He213 Jafari, Roghayeh aut Enthalten in Journal of polymer research Dordrecht : Springer Science + Business Media B.V., 1994 30(2023), 10 vom: 29. Sept. (DE-627)340872098 (DE-600)2065616-6 1572-8935 nnns volume:30 year:2023 number:10 day:29 month:09 https://dx.doi.org/10.1007/s10965-023-03769-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2023 10 29 09
allfields_unstemmed	10.1007/s10965-023-03769-5 doi (DE-627)SPR053234324 (SPR)s10965-023-03769-5-e DE-627 ger DE-627 rakwb eng Bardajee, Ghasem Rezanejade verfasserin (orcid)0000-0001-7331-0059 aut Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied. Nanogel synthesis (dpeaa)DE-He213 Interpenetrating networks nanogels (dpeaa)DE-He213 Drug release (dpeaa)DE-He213 Alginate biopolymer (dpeaa)DE-He213 Jafari, Roghayeh aut Enthalten in Journal of polymer research Dordrecht : Springer Science + Business Media B.V., 1994 30(2023), 10 vom: 29. Sept. (DE-627)340872098 (DE-600)2065616-6 1572-8935 nnns volume:30 year:2023 number:10 day:29 month:09 https://dx.doi.org/10.1007/s10965-023-03769-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2023 10 29 09
allfieldsGer	10.1007/s10965-023-03769-5 doi (DE-627)SPR053234324 (SPR)s10965-023-03769-5-e DE-627 ger DE-627 rakwb eng Bardajee, Ghasem Rezanejade verfasserin (orcid)0000-0001-7331-0059 aut Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied. Nanogel synthesis (dpeaa)DE-He213 Interpenetrating networks nanogels (dpeaa)DE-He213 Drug release (dpeaa)DE-He213 Alginate biopolymer (dpeaa)DE-He213 Jafari, Roghayeh aut Enthalten in Journal of polymer research Dordrecht : Springer Science + Business Media B.V., 1994 30(2023), 10 vom: 29. Sept. (DE-627)340872098 (DE-600)2065616-6 1572-8935 nnns volume:30 year:2023 number:10 day:29 month:09 https://dx.doi.org/10.1007/s10965-023-03769-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2023 10 29 09
allfieldsSound	10.1007/s10965-023-03769-5 doi (DE-627)SPR053234324 (SPR)s10965-023-03769-5-e DE-627 ger DE-627 rakwb eng Bardajee, Ghasem Rezanejade verfasserin (orcid)0000-0001-7331-0059 aut Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX) 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied. Nanogel synthesis (dpeaa)DE-He213 Interpenetrating networks nanogels (dpeaa)DE-He213 Drug release (dpeaa)DE-He213 Alginate biopolymer (dpeaa)DE-He213 Jafari, Roghayeh aut Enthalten in Journal of polymer research Dordrecht : Springer Science + Business Media B.V., 1994 30(2023), 10 vom: 29. Sept. (DE-627)340872098 (DE-600)2065616-6 1572-8935 nnns volume:30 year:2023 number:10 day:29 month:09 https://dx.doi.org/10.1007/s10965-023-03769-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2023 10 29 09
language	English
source	Enthalten in Journal of polymer research 30(2023), 10 vom: 29. Sept. volume:30 year:2023 number:10 day:29 month:09
sourceStr	Enthalten in Journal of polymer research 30(2023), 10 vom: 29. Sept. volume:30 year:2023 number:10 day:29 month:09
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Nanogel synthesis Interpenetrating networks nanogels Drug release Alginate biopolymer
isfreeaccess_bool	false
container_title	Journal of polymer research
authorswithroles_txt_mv	Bardajee, Ghasem Rezanejade @@aut@@ Jafari, Roghayeh @@aut@@
publishDateDaySort_date	2023-09-29T00:00:00Z
hierarchy_top_id	340872098
id	SPR053234324
language_de	englisch
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author	Bardajee, Ghasem Rezanejade
spellingShingle	Bardajee, Ghasem Rezanejade misc Nanogel synthesis misc Interpenetrating networks nanogels misc Drug release misc Alginate biopolymer Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX)
authorStr	Bardajee, Ghasem Rezanejade
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topic_title	Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX) Nanogel synthesis (dpeaa)DE-He213 Interpenetrating networks nanogels (dpeaa)DE-He213 Drug release (dpeaa)DE-He213 Alginate biopolymer (dpeaa)DE-He213
topic	misc Nanogel synthesis misc Interpenetrating networks nanogels misc Drug release misc Alginate biopolymer
topic_unstemmed	misc Nanogel synthesis misc Interpenetrating networks nanogels misc Drug release misc Alginate biopolymer
topic_browse	misc Nanogel synthesis misc Interpenetrating networks nanogels misc Drug release misc Alginate biopolymer
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title	Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX)
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title_full	Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX)
author_sort	Bardajee, Ghasem Rezanejade
journal	Journal of polymer research
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author_browse	Bardajee, Ghasem Rezanejade Jafari, Roghayeh
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author-letter	Bardajee, Ghasem Rezanejade
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title_sort	synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (dox)
title_auth	Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX)
abstract	Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied. © The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
abstractGer	Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied. © The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
abstract_unstemmed	Abstract A new one-pot method for the synthesis of interpenetrating polymer networks nanogels of sodium alginate-co-poly (2-(dimethylamino)ethyl methacrylate) [AG-PDMAEMA] with novel properties is described. Monomers solution consists of sodium alginate biopolymer, 2-(dimethylamino)ethyl methacrylate (DMAEMA) monomer, crosslinker, and initiator in water, as water phase, are used to produce water in oil (W/O) emulsion, stabilized by polyethylene glycol sorbitan monolaurate (Tween 80) and sorbitan monooleate (Span 80) at room temperature. $ CaCl_{2} $ nanoparticles are synthesized and finally added to the emulsion. To obtain interpenetrating networks hydrogel, crosslinking agent N, Nʼ-methylenebisacrylamide (MBA) and $ Ca^{2+} $ cations are used to crosslink poly(2-(dimethylamino)ethyl methacrylate) and sodium alginate polymers, respectively. Prepared interpenetrating networks nanogel were employed for entrapping and releasing the model anticancer drug doxorubicin (DOX). The obtainedinterpenetrating polymer networks were characterized by field emission scanning electron microscopy (FE-SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), thermogravimetric analysis (TGA) and dynamic light scattering (DLS). In addition, the swelling properties of nanogels in water and the release behavior of the model drug from that were also studied. © The Polymer Society, Taipei 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
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container_issue	10
title_short	Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX)
url	https://dx.doi.org/10.1007/s10965-023-03769-5
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author2	Jafari, Roghayeh
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doi_str	10.1007/s10965-023-03769-5
up_date	2024-07-03T18:02:21.942Z
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Synthesis of interpenetrating networks nanogels based on sodium alginate and 2-(dimethylamino) ethyl methacrylate and application as drug release of the anticancer doxorubicin (DOX)

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