Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary

Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Pat...
Ausführliche Beschreibung

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Autor*in:	Yang, Si-Si [verfasserIn] Huang, Wen-Chang Wang, Peng Gong, Fang-Qi Liu, Tai-Xiang Tou, Jin-Fa Lai, Deng-Ming

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Omphalocele Pulmonary hypertension Echocardiogram Left ventricle Prognosis

Anmerkung:	© The Author(s) 2023

Übergeordnetes Werk:	Enthalten in: BMC pediatrics - London : BioMed Central, 2001, 23(2023), 1 vom: 22. Nov.
Übergeordnetes Werk:	volume:23 ; year:2023 ; number:1 ; day:22 ; month:11

Links:	Volltext

DOI / URN:	10.1186/s12887-023-04418-y

Katalog-ID:	SPR05381777X

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245	1	0	\|a Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary
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520			\|a Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III.
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allfields	10.1186/s12887-023-04418-y doi (DE-627)SPR05381777X (SPR)s12887-023-04418-y-e DE-627 ger DE-627 rakwb eng Yang, Si-Si verfasserin aut Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III. Omphalocele (dpeaa)DE-He213 Pulmonary hypertension (dpeaa)DE-He213 Echocardiogram (dpeaa)DE-He213 Left ventricle (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Huang, Wen-Chang aut Wang, Peng aut Gong, Fang-Qi aut Liu, Tai-Xiang aut Tou, Jin-Fa aut Lai, Deng-Ming aut Enthalten in BMC pediatrics London : BioMed Central, 2001 23(2023), 1 vom: 22. Nov. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:23 year:2023 number:1 day:22 month:11 https://dx.doi.org/10.1186/s12887-023-04418-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2023 1 22 11
spelling	10.1186/s12887-023-04418-y doi (DE-627)SPR05381777X (SPR)s12887-023-04418-y-e DE-627 ger DE-627 rakwb eng Yang, Si-Si verfasserin aut Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III. Omphalocele (dpeaa)DE-He213 Pulmonary hypertension (dpeaa)DE-He213 Echocardiogram (dpeaa)DE-He213 Left ventricle (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Huang, Wen-Chang aut Wang, Peng aut Gong, Fang-Qi aut Liu, Tai-Xiang aut Tou, Jin-Fa aut Lai, Deng-Ming aut Enthalten in BMC pediatrics London : BioMed Central, 2001 23(2023), 1 vom: 22. Nov. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:23 year:2023 number:1 day:22 month:11 https://dx.doi.org/10.1186/s12887-023-04418-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2023 1 22 11
allfields_unstemmed	10.1186/s12887-023-04418-y doi (DE-627)SPR05381777X (SPR)s12887-023-04418-y-e DE-627 ger DE-627 rakwb eng Yang, Si-Si verfasserin aut Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III. Omphalocele (dpeaa)DE-He213 Pulmonary hypertension (dpeaa)DE-He213 Echocardiogram (dpeaa)DE-He213 Left ventricle (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Huang, Wen-Chang aut Wang, Peng aut Gong, Fang-Qi aut Liu, Tai-Xiang aut Tou, Jin-Fa aut Lai, Deng-Ming aut Enthalten in BMC pediatrics London : BioMed Central, 2001 23(2023), 1 vom: 22. Nov. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:23 year:2023 number:1 day:22 month:11 https://dx.doi.org/10.1186/s12887-023-04418-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2023 1 22 11
allfieldsGer	10.1186/s12887-023-04418-y doi (DE-627)SPR05381777X (SPR)s12887-023-04418-y-e DE-627 ger DE-627 rakwb eng Yang, Si-Si verfasserin aut Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III. Omphalocele (dpeaa)DE-He213 Pulmonary hypertension (dpeaa)DE-He213 Echocardiogram (dpeaa)DE-He213 Left ventricle (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Huang, Wen-Chang aut Wang, Peng aut Gong, Fang-Qi aut Liu, Tai-Xiang aut Tou, Jin-Fa aut Lai, Deng-Ming aut Enthalten in BMC pediatrics London : BioMed Central, 2001 23(2023), 1 vom: 22. Nov. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:23 year:2023 number:1 day:22 month:11 https://dx.doi.org/10.1186/s12887-023-04418-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2023 1 22 11
allfieldsSound	10.1186/s12887-023-04418-y doi (DE-627)SPR05381777X (SPR)s12887-023-04418-y-e DE-627 ger DE-627 rakwb eng Yang, Si-Si verfasserin aut Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III. Omphalocele (dpeaa)DE-He213 Pulmonary hypertension (dpeaa)DE-He213 Echocardiogram (dpeaa)DE-He213 Left ventricle (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Huang, Wen-Chang aut Wang, Peng aut Gong, Fang-Qi aut Liu, Tai-Xiang aut Tou, Jin-Fa aut Lai, Deng-Ming aut Enthalten in BMC pediatrics London : BioMed Central, 2001 23(2023), 1 vom: 22. Nov. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:23 year:2023 number:1 day:22 month:11 https://dx.doi.org/10.1186/s12887-023-04418-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2023 1 22 11
language	English
source	Enthalten in BMC pediatrics 23(2023), 1 vom: 22. Nov. volume:23 year:2023 number:1 day:22 month:11
sourceStr	Enthalten in BMC pediatrics 23(2023), 1 vom: 22. Nov. volume:23 year:2023 number:1 day:22 month:11
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Omphalocele Pulmonary hypertension Echocardiogram Left ventricle Prognosis
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container_title	BMC pediatrics
authorswithroles_txt_mv	Yang, Si-Si @@aut@@ Huang, Wen-Chang @@aut@@ Wang, Peng @@aut@@ Gong, Fang-Qi @@aut@@ Liu, Tai-Xiang @@aut@@ Tou, Jin-Fa @@aut@@ Lai, Deng-Ming @@aut@@
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Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. 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author	Yang, Si-Si
spellingShingle	Yang, Si-Si misc Omphalocele misc Pulmonary hypertension misc Echocardiogram misc Left ventricle misc Prognosis Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary
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topic_title	Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary Omphalocele (dpeaa)DE-He213 Pulmonary hypertension (dpeaa)DE-He213 Echocardiogram (dpeaa)DE-He213 Left ventricle (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213
topic	misc Omphalocele misc Pulmonary hypertension misc Echocardiogram misc Left ventricle misc Prognosis
topic_unstemmed	misc Omphalocele misc Pulmonary hypertension misc Echocardiogram misc Left ventricle misc Prognosis
topic_browse	misc Omphalocele misc Pulmonary hypertension misc Echocardiogram misc Left ventricle misc Prognosis
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title	Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary
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title_full	Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary
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author_browse	Yang, Si-Si Huang, Wen-Chang Wang, Peng Gong, Fang-Qi Liu, Tai-Xiang Tou, Jin-Fa Lai, Deng-Ming
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author-letter	Yang, Si-Si
doi_str_mv	10.1186/s12887-023-04418-y
title_sort	echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary
title_auth	Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary
abstract	Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III. © The Author(s) 2023
abstractGer	Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III. © The Author(s) 2023
abstract_unstemmed	Purpose The purpose of this study was to explore echocardiographic parameters of the left ventricle (LV) in relation to the outcomes of omphalocele neonates with pulmonary hypertension (PH). Methods This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have additional severe malformations or chromosomal aberrations. Patients who died under palliative care were excluded. The echocardiographic parameters of LV were obtained within 24 h after birth. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal dimension in end-diastole (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others. Results There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Both groups were comparable in the baseline characteristics. Non-survival was associated with a smaller LV [LVIDd (12.2 mm versus15.7 mm, p < 0.05), EDV (3.5 ml versus 6.8 ml, p < 0.05)] and with worse systolic function [SV (2.3 ml versus 4.2 ml, p < 0.05), and CI (1.7 L/min/$ m^{2} $ versus 2.9 L/min/$ m^{2} $, p < 0.01)]. Conclusion In the cohort of omphalocele patients with PH, lower LVIDd, EDV, SV and CI were associated with mortality. Level of evidence Level III. © The Author(s) 2023
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title_short	Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary
url	https://dx.doi.org/10.1186/s12887-023-04418-y
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author2	Huang, Wen-Chang Wang, Peng Gong, Fang-Qi Liu, Tai-Xiang Tou, Jin-Fa Lai, Deng-Ming
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up_date	2024-07-03T22:14:28.791Z
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Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary

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