Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates

Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Jeong, Yeonwoo [verfasserIn] Kim, Inho Kang, Sung Min

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Alginate Zirconium pDA Coating Non-biofouling property Long-term stability

Anmerkung:	© The Author(s), under exclusive licence to The Polymer Society of Korea 2023

Übergeordnetes Werk:	Enthalten in: Macromolecular research - Heidelberg : Springer, 2010, 32(2023), 1 vom: 28. Sept., Seite 85-90
Übergeordnetes Werk:	volume:32 ; year:2023 ; number:1 ; day:28 ; month:09 ; pages:85-90

Links:	Volltext

DOI / URN:	10.1007/s13233-023-00203-z

Katalog-ID:	SPR054412455

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520			\|a Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively.
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912			\|a GBV_ILN_138
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
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912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_171
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_250
912			\|a GBV_ILN_281
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_636
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
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912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2031
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2037
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2039
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2057
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2093
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2107
912			\|a GBV_ILN_2108
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
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allfields	10.1007/s13233-023-00203-z doi (DE-627)SPR054412455 (SPR)s13233-023-00203-z-e DE-627 ger DE-627 rakwb eng Jeong, Yeonwoo verfasserin aut Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to The Polymer Society of Korea 2023 Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively. Alginate (dpeaa)DE-He213 Zirconium (dpeaa)DE-He213 pDA Coating (dpeaa)DE-He213 Non-biofouling property (dpeaa)DE-He213 Long-term stability (dpeaa)DE-He213 Kim, Inho aut Kang, Sung Min (orcid)0000-0002-9273-1585 aut Enthalten in Macromolecular research Heidelberg : Springer, 2010 32(2023), 1 vom: 28. Sept., Seite 85-90 (DE-627)618327576 (DE-600)2537708-5 2092-7673 nnns volume:32 year:2023 number:1 day:28 month:09 pages:85-90 https://dx.doi.org/10.1007/s13233-023-00203-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 32 2023 1 28 09 85-90
spelling	10.1007/s13233-023-00203-z doi (DE-627)SPR054412455 (SPR)s13233-023-00203-z-e DE-627 ger DE-627 rakwb eng Jeong, Yeonwoo verfasserin aut Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to The Polymer Society of Korea 2023 Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively. Alginate (dpeaa)DE-He213 Zirconium (dpeaa)DE-He213 pDA Coating (dpeaa)DE-He213 Non-biofouling property (dpeaa)DE-He213 Long-term stability (dpeaa)DE-He213 Kim, Inho aut Kang, Sung Min (orcid)0000-0002-9273-1585 aut Enthalten in Macromolecular research Heidelberg : Springer, 2010 32(2023), 1 vom: 28. Sept., Seite 85-90 (DE-627)618327576 (DE-600)2537708-5 2092-7673 nnns volume:32 year:2023 number:1 day:28 month:09 pages:85-90 https://dx.doi.org/10.1007/s13233-023-00203-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 32 2023 1 28 09 85-90
allfields_unstemmed	10.1007/s13233-023-00203-z doi (DE-627)SPR054412455 (SPR)s13233-023-00203-z-e DE-627 ger DE-627 rakwb eng Jeong, Yeonwoo verfasserin aut Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to The Polymer Society of Korea 2023 Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively. Alginate (dpeaa)DE-He213 Zirconium (dpeaa)DE-He213 pDA Coating (dpeaa)DE-He213 Non-biofouling property (dpeaa)DE-He213 Long-term stability (dpeaa)DE-He213 Kim, Inho aut Kang, Sung Min (orcid)0000-0002-9273-1585 aut Enthalten in Macromolecular research Heidelberg : Springer, 2010 32(2023), 1 vom: 28. Sept., Seite 85-90 (DE-627)618327576 (DE-600)2537708-5 2092-7673 nnns volume:32 year:2023 number:1 day:28 month:09 pages:85-90 https://dx.doi.org/10.1007/s13233-023-00203-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 32 2023 1 28 09 85-90
allfieldsGer	10.1007/s13233-023-00203-z doi (DE-627)SPR054412455 (SPR)s13233-023-00203-z-e DE-627 ger DE-627 rakwb eng Jeong, Yeonwoo verfasserin aut Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to The Polymer Society of Korea 2023 Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively. Alginate (dpeaa)DE-He213 Zirconium (dpeaa)DE-He213 pDA Coating (dpeaa)DE-He213 Non-biofouling property (dpeaa)DE-He213 Long-term stability (dpeaa)DE-He213 Kim, Inho aut Kang, Sung Min (orcid)0000-0002-9273-1585 aut Enthalten in Macromolecular research Heidelberg : Springer, 2010 32(2023), 1 vom: 28. Sept., Seite 85-90 (DE-627)618327576 (DE-600)2537708-5 2092-7673 nnns volume:32 year:2023 number:1 day:28 month:09 pages:85-90 https://dx.doi.org/10.1007/s13233-023-00203-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 32 2023 1 28 09 85-90
allfieldsSound	10.1007/s13233-023-00203-z doi (DE-627)SPR054412455 (SPR)s13233-023-00203-z-e DE-627 ger DE-627 rakwb eng Jeong, Yeonwoo verfasserin aut Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to The Polymer Society of Korea 2023 Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively. Alginate (dpeaa)DE-He213 Zirconium (dpeaa)DE-He213 pDA Coating (dpeaa)DE-He213 Non-biofouling property (dpeaa)DE-He213 Long-term stability (dpeaa)DE-He213 Kim, Inho aut Kang, Sung Min (orcid)0000-0002-9273-1585 aut Enthalten in Macromolecular research Heidelberg : Springer, 2010 32(2023), 1 vom: 28. Sept., Seite 85-90 (DE-627)618327576 (DE-600)2537708-5 2092-7673 nnns volume:32 year:2023 number:1 day:28 month:09 pages:85-90 https://dx.doi.org/10.1007/s13233-023-00203-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 32 2023 1 28 09 85-90
language	English
source	Enthalten in Macromolecular research 32(2023), 1 vom: 28. Sept., Seite 85-90 volume:32 year:2023 number:1 day:28 month:09 pages:85-90
sourceStr	Enthalten in Macromolecular research 32(2023), 1 vom: 28. Sept., Seite 85-90 volume:32 year:2023 number:1 day:28 month:09 pages:85-90
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Alginate Zirconium pDA Coating Non-biofouling property Long-term stability
isfreeaccess_bool	false
container_title	Macromolecular research
authorswithroles_txt_mv	Jeong, Yeonwoo @@aut@@ Kim, Inho @@aut@@ Kang, Sung Min @@aut@@
publishDateDaySort_date	2023-09-28T00:00:00Z
hierarchy_top_id	618327576
id	SPR054412455
language_de	englisch
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author	Jeong, Yeonwoo
spellingShingle	Jeong, Yeonwoo misc Alginate misc Zirconium misc pDA Coating misc Non-biofouling property misc Long-term stability Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates
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topic_title	Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates Alginate (dpeaa)DE-He213 Zirconium (dpeaa)DE-He213 pDA Coating (dpeaa)DE-He213 Non-biofouling property (dpeaa)DE-He213 Long-term stability (dpeaa)DE-He213
topic	misc Alginate misc Zirconium misc pDA Coating misc Non-biofouling property misc Long-term stability
topic_unstemmed	misc Alginate misc Zirconium misc pDA Coating misc Non-biofouling property misc Long-term stability
topic_browse	misc Alginate misc Zirconium misc pDA Coating misc Non-biofouling property misc Long-term stability
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title	Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates
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title_full	Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates
author_sort	Jeong, Yeonwoo
journal	Macromolecular research
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author_browse	Jeong, Yeonwoo Kim, Inho Kang, Sung Min
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author-letter	Jeong, Yeonwoo
doi_str_mv	10.1007/s13233-023-00203-z
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title_sort	stability of non-biofouling alginate/$ zr^{iv} $ coatings on ti/$ tio_{2} $ substrates
title_auth	Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates
abstract	Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively. © The Author(s), under exclusive licence to The Polymer Society of Korea 2023
abstractGer	Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively. © The Author(s), under exclusive licence to The Polymer Society of Korea 2023
abstract_unstemmed	Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. The Alg coatings maintain their antiprotein adsorption and antiplatelet adhesion properties at high percentages of up to 80% and 90%, respectively. © The Author(s), under exclusive licence to The Polymer Society of Korea 2023
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title_short	Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates
url	https://dx.doi.org/10.1007/s13233-023-00203-z
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author2	Kim, Inho Kang, Sung Min
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doi_str	10.1007/s13233-023-00203-z
up_date	2024-07-04T01:29:49.839Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">SPR054412455</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240117064702.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240117s2023 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s13233-023-00203-z</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR054412455</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s13233-023-00203-z-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Jeong, Yeonwoo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2023</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© The Author(s), under exclusive licence to The Polymer Society of Korea 2023</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Surface modification with alginate (Alg) has attracted significant attention because of its potential applications in non-biofouling surface preparation, tissue engineering, and drug delivery. Much effort has been made to develop facile methods for preparing stable Alg coatings, including metal ion-mediated cross-link formation between polydopamine-coated solid surfaces and Alg. Although this approach has yielded Alg coatings that strongly inhibit platelet adhesion and fibrinogen adsorption on solid surfaces, their long-term stability, which is a prerequisite for practical applications, remains unknown. This study evaluated the long-term stability of Alg coatings under physiological conditions. The Alg coatings were incubated in phosphate-buffered saline at 37.5 °C for up to four weeks and subsequently analyzed for non-biofouling properties. The analysis revealed that the anti-protein adsorption and antiplatelet adhesion properties of the Alg coating were maintained at 80 and 90%, respectively, after four weeks of incubation. This study provides valuable insights into the long-term stability of Alg coatings and their potential for practical applications, addressing an overlooked crucial aspect. The findings contribute to advancements in tissue engineering, drug delivery systems, and other biomedical applications by enhancing our understanding of Alg coatings' durability and guiding the design of robust non-biofouling materials. Graphical abstract The long-term stability of alginate (Alg) coatings under physiological conditions is evaluated. Alg coatings are prepared using metal ion-mediated cross-link formation and subject to four weeks of incubation in phosphate-buffered saline at 37.5 °C. 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Stability of non-biofouling alginate/$ Zr^{IV} $ coatings on Ti/$ TiO_{2} $ substrates

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