Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr
Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-c...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Masuda, Shinichiro [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020 |
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| Anmerkung: |
© Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 |
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| Übergeordnetes Werk: |
Enthalten in: Artery research - Amsterdam : Atlantis Press, 2006, 26(2020), 3 vom: 26. Juni, Seite 143-147 |
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| Übergeordnetes Werk: |
volume:26 ; year:2020 ; number:3 ; day:26 ; month:06 ; pages:143-147 |
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| DOI / URN: |
10.2991/artres.k.200620.001 |
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SPR054726875 |
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| 520 | |a Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. | ||
| 520 | |a Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. | ||
| 650 | 4 | |a Instantaneous wave-free ratio |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a pressure study |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a reliability |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a diagnostic catheter |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Uemura, Ryota |4 aut | |
| 700 | 1 | |a Saiki, Yoshiyuki |4 aut | |
| 700 | 1 | |a Haraki, Tatsuo |4 aut | |
| 700 | 1 | |a Lee, Takeshi |4 aut | |
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10.2991/artres.k.200620.001 doi (DE-627)SPR054726875 (SPR)artres.k.200620.001-e DE-627 ger DE-627 rakwb eng Masuda, Shinichiro verfasserin (orcid)0000-0002-2791-8538 aut Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. Instantaneous wave-free ratio (dpeaa)DE-He213 pressure study (dpeaa)DE-He213 reliability (dpeaa)DE-He213 diagnostic catheter (dpeaa)DE-He213 Uemura, Ryota aut Saiki, Yoshiyuki aut Haraki, Tatsuo aut Lee, Takeshi aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), 3 vom: 26. Juni, Seite 143-147 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:3 day:26 month:06 pages:143-147 https://dx.doi.org/10.2991/artres.k.200620.001 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 3 26 06 143-147 |
| spelling |
10.2991/artres.k.200620.001 doi (DE-627)SPR054726875 (SPR)artres.k.200620.001-e DE-627 ger DE-627 rakwb eng Masuda, Shinichiro verfasserin (orcid)0000-0002-2791-8538 aut Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. Instantaneous wave-free ratio (dpeaa)DE-He213 pressure study (dpeaa)DE-He213 reliability (dpeaa)DE-He213 diagnostic catheter (dpeaa)DE-He213 Uemura, Ryota aut Saiki, Yoshiyuki aut Haraki, Tatsuo aut Lee, Takeshi aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), 3 vom: 26. Juni, Seite 143-147 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:3 day:26 month:06 pages:143-147 https://dx.doi.org/10.2991/artres.k.200620.001 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 3 26 06 143-147 |
| allfields_unstemmed |
10.2991/artres.k.200620.001 doi (DE-627)SPR054726875 (SPR)artres.k.200620.001-e DE-627 ger DE-627 rakwb eng Masuda, Shinichiro verfasserin (orcid)0000-0002-2791-8538 aut Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. Instantaneous wave-free ratio (dpeaa)DE-He213 pressure study (dpeaa)DE-He213 reliability (dpeaa)DE-He213 diagnostic catheter (dpeaa)DE-He213 Uemura, Ryota aut Saiki, Yoshiyuki aut Haraki, Tatsuo aut Lee, Takeshi aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), 3 vom: 26. Juni, Seite 143-147 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:3 day:26 month:06 pages:143-147 https://dx.doi.org/10.2991/artres.k.200620.001 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 3 26 06 143-147 |
| allfieldsGer |
10.2991/artres.k.200620.001 doi (DE-627)SPR054726875 (SPR)artres.k.200620.001-e DE-627 ger DE-627 rakwb eng Masuda, Shinichiro verfasserin (orcid)0000-0002-2791-8538 aut Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. Instantaneous wave-free ratio (dpeaa)DE-He213 pressure study (dpeaa)DE-He213 reliability (dpeaa)DE-He213 diagnostic catheter (dpeaa)DE-He213 Uemura, Ryota aut Saiki, Yoshiyuki aut Haraki, Tatsuo aut Lee, Takeshi aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), 3 vom: 26. Juni, Seite 143-147 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:3 day:26 month:06 pages:143-147 https://dx.doi.org/10.2991/artres.k.200620.001 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 3 26 06 143-147 |
| allfieldsSound |
10.2991/artres.k.200620.001 doi (DE-627)SPR054726875 (SPR)artres.k.200620.001-e DE-627 ger DE-627 rakwb eng Masuda, Shinichiro verfasserin (orcid)0000-0002-2791-8538 aut Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. Instantaneous wave-free ratio (dpeaa)DE-He213 pressure study (dpeaa)DE-He213 reliability (dpeaa)DE-He213 diagnostic catheter (dpeaa)DE-He213 Uemura, Ryota aut Saiki, Yoshiyuki aut Haraki, Tatsuo aut Lee, Takeshi aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), 3 vom: 26. Juni, Seite 143-147 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:3 day:26 month:06 pages:143-147 https://dx.doi.org/10.2991/artres.k.200620.001 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 3 26 06 143-147 |
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Enthalten in Artery research 26(2020), 3 vom: 26. Juni, Seite 143-147 volume:26 year:2020 number:3 day:26 month:06 pages:143-147 |
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Publishing services by Atlantis Press International B.V. 2020</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. 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Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr |
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Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. © Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 |
| abstractGer |
Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. © Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 |
| abstract_unstemmed |
Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values. © Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V. 2020 |
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Publishing services by Atlantis Press International B.V. 2020</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland—Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Highlights Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.Correlation and agreement of iFR between 4Fr and 5Fr.To compare the successful measurement of iFR values.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Instantaneous wave-free ratio</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">pressure study</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">reliability</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">diagnostic catheter</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Uemura, Ryota</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Saiki, Yoshiyuki</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Haraki, Tatsuo</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lee, Takeshi</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Artery research</subfield><subfield code="d">Amsterdam : Atlantis Press, 2006</subfield><subfield code="g">26(2020), 3 vom: 26. 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