1.3 Past Smokers Decelerate Vascular Aging in the Long Term

Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51...
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Autor*in:	Terentes-Printzios, Dimitrios [verfasserIn] Vlachopoulos, Charalambos Ioakeimidis, Nikolaos Aggelis, Athanasios Xaplanteris, Panagiotis Pietri, Panagiota Tousoulis, Dimitrios

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Anmerkung:	© Association for Research into Arterial Structure and Physiology 2015

Übergeordnetes Werk:	Enthalten in: Artery research - Amsterdam : Atlantis Press, 2006, 12(2015), 1 vom: 23. Nov., Seite 39-40
Übergeordnetes Werk:	volume:12 ; year:2015 ; number:1 ; day:23 ; month:11 ; pages:39-40

Links:	Volltext

DOI / URN:	10.1016/j.artres.2015.10.004

Katalog-ID:	SPR054759056

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520			\|a Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age.
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allfields	10.1016/j.artres.2015.10.004 doi (DE-627)SPR054759056 (SPR)j.artres.2015.10.004-e DE-627 ger DE-627 rakwb eng Terentes-Printzios, Dimitrios verfasserin aut 1.3 Past Smokers Decelerate Vascular Aging in the Long Term 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2015 Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age. Vlachopoulos, Charalambos aut Ioakeimidis, Nikolaos aut Aggelis, Athanasios aut Xaplanteris, Panagiotis aut Pietri, Panagiota aut Tousoulis, Dimitrios aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 12(2015), 1 vom: 23. Nov., Seite 39-40 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:12 year:2015 number:1 day:23 month:11 pages:39-40 https://dx.doi.org/10.1016/j.artres.2015.10.004 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2015 1 23 11 39-40
spelling	10.1016/j.artres.2015.10.004 doi (DE-627)SPR054759056 (SPR)j.artres.2015.10.004-e DE-627 ger DE-627 rakwb eng Terentes-Printzios, Dimitrios verfasserin aut 1.3 Past Smokers Decelerate Vascular Aging in the Long Term 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2015 Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age. Vlachopoulos, Charalambos aut Ioakeimidis, Nikolaos aut Aggelis, Athanasios aut Xaplanteris, Panagiotis aut Pietri, Panagiota aut Tousoulis, Dimitrios aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 12(2015), 1 vom: 23. Nov., Seite 39-40 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:12 year:2015 number:1 day:23 month:11 pages:39-40 https://dx.doi.org/10.1016/j.artres.2015.10.004 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2015 1 23 11 39-40
allfields_unstemmed	10.1016/j.artres.2015.10.004 doi (DE-627)SPR054759056 (SPR)j.artres.2015.10.004-e DE-627 ger DE-627 rakwb eng Terentes-Printzios, Dimitrios verfasserin aut 1.3 Past Smokers Decelerate Vascular Aging in the Long Term 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2015 Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age. Vlachopoulos, Charalambos aut Ioakeimidis, Nikolaos aut Aggelis, Athanasios aut Xaplanteris, Panagiotis aut Pietri, Panagiota aut Tousoulis, Dimitrios aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 12(2015), 1 vom: 23. Nov., Seite 39-40 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:12 year:2015 number:1 day:23 month:11 pages:39-40 https://dx.doi.org/10.1016/j.artres.2015.10.004 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2015 1 23 11 39-40
allfieldsGer	10.1016/j.artres.2015.10.004 doi (DE-627)SPR054759056 (SPR)j.artres.2015.10.004-e DE-627 ger DE-627 rakwb eng Terentes-Printzios, Dimitrios verfasserin aut 1.3 Past Smokers Decelerate Vascular Aging in the Long Term 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2015 Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age. Vlachopoulos, Charalambos aut Ioakeimidis, Nikolaos aut Aggelis, Athanasios aut Xaplanteris, Panagiotis aut Pietri, Panagiota aut Tousoulis, Dimitrios aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 12(2015), 1 vom: 23. Nov., Seite 39-40 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:12 year:2015 number:1 day:23 month:11 pages:39-40 https://dx.doi.org/10.1016/j.artres.2015.10.004 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2015 1 23 11 39-40
allfieldsSound	10.1016/j.artres.2015.10.004 doi (DE-627)SPR054759056 (SPR)j.artres.2015.10.004-e DE-627 ger DE-627 rakwb eng Terentes-Printzios, Dimitrios verfasserin aut 1.3 Past Smokers Decelerate Vascular Aging in the Long Term 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2015 Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age. Vlachopoulos, Charalambos aut Ioakeimidis, Nikolaos aut Aggelis, Athanasios aut Xaplanteris, Panagiotis aut Pietri, Panagiota aut Tousoulis, Dimitrios aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 12(2015), 1 vom: 23. Nov., Seite 39-40 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:12 year:2015 number:1 day:23 month:11 pages:39-40 https://dx.doi.org/10.1016/j.artres.2015.10.004 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2015 1 23 11 39-40
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In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Vlachopoulos, Charalambos</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ioakeimidis, Nikolaos</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Aggelis, Athanasios</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Xaplanteris, Panagiotis</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pietri, Panagiota</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tousoulis, Dimitrios</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Artery research</subfield><subfield code="d">Amsterdam : Atlantis Press, 2006</subfield><subfield code="g">12(2015), 1 vom: 23. 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author	Terentes-Printzios, Dimitrios
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topic_title	1.3 Past Smokers Decelerate Vascular Aging in the Long Term
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title	1.3 Past Smokers Decelerate Vascular Aging in the Long Term
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title_full	1.3 Past Smokers Decelerate Vascular Aging in the Long Term
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author_browse	Terentes-Printzios, Dimitrios Vlachopoulos, Charalambos Ioakeimidis, Nikolaos Aggelis, Athanasios Xaplanteris, Panagiotis Pietri, Panagiota Tousoulis, Dimitrios
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author-letter	Terentes-Printzios, Dimitrios
doi_str_mv	10.1016/j.artres.2015.10.004
title_sort	1.3 past smokers decelerate vascular aging in the long term
title_auth	1.3 Past Smokers Decelerate Vascular Aging in the Long Term
abstract	Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age. © Association for Research into Arterial Structure and Physiology 2015
abstractGer	Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age. © Association for Research into Arterial Structure and Physiology 2015
abstract_unstemmed	Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods Of 6643 London children, aged 11e13 y, from 51 schools in samples of about 1000 in 6 ethnic groups, with markedly different adult cardiovascular risk, 4785 (72%), were seen again at 14e16 y. In 2013, 666 (97% of invited) took part in a young-adult pilot (21–23 y) follow-up. With psychosocial, anthropometric and BP measures, PWV was recorded via an upper arm cuff on the calibrated Arteriograph device. In a subsample (n = 334) PA was measured over 5 days via the ActivPal. Results Unadjusted PWVs in Black Caribbean and White UK young men were similar (mean+SD 7.9 + 0.3 vs 7.6 + 0.4 m/sec) and lower in other groups at similar systolic (s)BPs (120 mmHg) and BMIs (24.6 kg/$ m^{2} $). In fully adjusted regression models, independent of BP effects, while Black Caribbean (higher BMIs and waists), Black African and Indian young women had lower PWV (by 0.5–0.8, 95%CI 0.1–1.1 m/sec) than White UK women (6.9 + 0.2 m/sec), values were still increased by age, BP, powerful impacts from waist/height and time spent sedentary but a reducing impact of time walking >100steps/min (both p < 0.01), with a racism effect (+0.4 m/sec) in women. Childhood effects of waist/hip were also detectable. Conclusion Even by young adulthood, increased waist/height ratios, lower physical activity, BP and psychosocial variables (eg: perceived racism) are independent determinants of arterial stiffness, likely to increase with age. © Association for Research into Arterial Structure and Physiology 2015
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title_short	1.3 Past Smokers Decelerate Vascular Aging in the Long Term
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author2	Vlachopoulos, Charalambos Ioakeimidis, Nikolaos Aggelis, Athanasios Xaplanteris, Panagiotis Pietri, Panagiota Tousoulis, Dimitrios
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up_date	2024-07-04T02:55:00.474Z
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