P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity

Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem...
Ausführliche Beschreibung

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Autor*in:	Cox, James [verfasserIn] Tan, Isabella Avolio, Alberto Butlin, Mark

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	Arterial stiffness measurement pulse transit time pulse wave velocity

Anmerkung:	© Association for Research into Arterial Structure and Physiology 2020

Übergeordnetes Werk:	Enthalten in: Artery research - Amsterdam : Atlantis Press, 2006, 26(2020), Suppl 1 vom: Dez., Seite S59-S59
Übergeordnetes Werk:	volume:26 ; year:2020 ; number:Suppl 1 ; month:12 ; pages:S59-S59

Links:	Volltext

DOI / URN:	10.2991/artres.k.201209.049

Katalog-ID:	SPR05476064X

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520			\|a Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV.
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allfields	10.2991/artres.k.201209.049 doi (DE-627)SPR05476064X (SPR)artres.k.201209.049-e DE-627 ger DE-627 rakwb eng Cox, James verfasserin aut P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2020 Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV. Arterial stiffness (dpeaa)DE-He213 measurement (dpeaa)DE-He213 pulse transit time (dpeaa)DE-He213 pulse wave velocity (dpeaa)DE-He213 Tan, Isabella aut Avolio, Alberto aut Butlin, Mark aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), Suppl 1 vom: Dez., Seite S59-S59 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:Suppl 1 month:12 pages:S59-S59 https://dx.doi.org/10.2991/artres.k.201209.049 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 Suppl 1 12 S59-S59
spelling	10.2991/artres.k.201209.049 doi (DE-627)SPR05476064X (SPR)artres.k.201209.049-e DE-627 ger DE-627 rakwb eng Cox, James verfasserin aut P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2020 Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV. Arterial stiffness (dpeaa)DE-He213 measurement (dpeaa)DE-He213 pulse transit time (dpeaa)DE-He213 pulse wave velocity (dpeaa)DE-He213 Tan, Isabella aut Avolio, Alberto aut Butlin, Mark aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), Suppl 1 vom: Dez., Seite S59-S59 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:Suppl 1 month:12 pages:S59-S59 https://dx.doi.org/10.2991/artres.k.201209.049 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 Suppl 1 12 S59-S59
allfields_unstemmed	10.2991/artres.k.201209.049 doi (DE-627)SPR05476064X (SPR)artres.k.201209.049-e DE-627 ger DE-627 rakwb eng Cox, James verfasserin aut P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2020 Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV. Arterial stiffness (dpeaa)DE-He213 measurement (dpeaa)DE-He213 pulse transit time (dpeaa)DE-He213 pulse wave velocity (dpeaa)DE-He213 Tan, Isabella aut Avolio, Alberto aut Butlin, Mark aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), Suppl 1 vom: Dez., Seite S59-S59 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:Suppl 1 month:12 pages:S59-S59 https://dx.doi.org/10.2991/artres.k.201209.049 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 Suppl 1 12 S59-S59
allfieldsGer	10.2991/artres.k.201209.049 doi (DE-627)SPR05476064X (SPR)artres.k.201209.049-e DE-627 ger DE-627 rakwb eng Cox, James verfasserin aut P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2020 Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV. Arterial stiffness (dpeaa)DE-He213 measurement (dpeaa)DE-He213 pulse transit time (dpeaa)DE-He213 pulse wave velocity (dpeaa)DE-He213 Tan, Isabella aut Avolio, Alberto aut Butlin, Mark aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), Suppl 1 vom: Dez., Seite S59-S59 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:Suppl 1 month:12 pages:S59-S59 https://dx.doi.org/10.2991/artres.k.201209.049 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 Suppl 1 12 S59-S59
allfieldsSound	10.2991/artres.k.201209.049 doi (DE-627)SPR05476064X (SPR)artres.k.201209.049-e DE-627 ger DE-627 rakwb eng Cox, James verfasserin aut P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Association for Research into Arterial Structure and Physiology 2020 Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV. Arterial stiffness (dpeaa)DE-He213 measurement (dpeaa)DE-He213 pulse transit time (dpeaa)DE-He213 pulse wave velocity (dpeaa)DE-He213 Tan, Isabella aut Avolio, Alberto aut Butlin, Mark aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 26(2020), Suppl 1 vom: Dez., Seite S59-S59 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:26 year:2020 number:Suppl 1 month:12 pages:S59-S59 https://dx.doi.org/10.2991/artres.k.201209.049 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2020 Suppl 1 12 S59-S59
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Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. 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author	Cox, James
spellingShingle	Cox, James misc Arterial stiffness misc measurement misc pulse transit time misc pulse wave velocity P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity
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topic_title	P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity Arterial stiffness (dpeaa)DE-He213 measurement (dpeaa)DE-He213 pulse transit time (dpeaa)DE-He213 pulse wave velocity (dpeaa)DE-He213
topic	misc Arterial stiffness misc measurement misc pulse transit time misc pulse wave velocity
topic_unstemmed	misc Arterial stiffness misc measurement misc pulse transit time misc pulse wave velocity
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title	P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity
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title_full	P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity
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title_sort	p.37 an assessment of potential sources of error that may arise in the measurement of carotid-femoral pulse wave velocity
title_auth	P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity
abstract	Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV. © Association for Research into Arterial Structure and Physiology 2020
abstractGer	Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV. © Association for Research into Arterial Structure and Physiology 2020
abstract_unstemmed	Objectives Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. Measurement error should not be a factor in the lack of clinical uptake of cfPWV. © Association for Research into Arterial Structure and Physiology 2020
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title_short	P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity
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Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem from potential measurement errors. This paper investigates the potential sources of error in the measurement of cfPWV. Methods Participants (n = 15, age 30 ± 15 years, 12 female) had supine cfPWV measured using the SphygmoCor XCEL device. Sources of error investigated included: 1) operator experience; 2) poor carotid waveform acquisition; 3) low placement of the leg cuff; and 4) tape measurement of distance. True cfPWV was obtained by averaging twenty cfPWV measurements (regression to the mean). Comparisons were made with regression analysis and Bland-Altman plots. Results All cfPWV measurements, for both the experienced and less experienced operator, were within ± 0.5 m/s of the true cfPWV when three (but not two) measurements were averaged. cfPWV acquired with a poor carotid waveform and lower placed leg cuf did not significantly differ from the measured cfPWV (p > 0.05), however, there were some physiological meaningful errors (cfPWV error > ± 0.5 m/s). Excluding four distance measurements, three of which made by the same operator for a single individual, all distance measurements were within 5% of the true distance. Conclusions Irrespective of the operators’ experience, with good cuff placement and carotid waveform acquisition, three measurements quantifies cfPWV accurately. 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P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity

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