P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model

Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure w...
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Autor*in:	Leguy, C. A. D. [verfasserIn] Boutouyrie, P. Bosboom, E. M. H. Bozec, E. Simons, L. Hoeks, A. P. G. Vosse, F. N.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2008

Anmerkung:	© Published by Elsevier. All rights reserved 2008

Übergeordnetes Werk:	Enthalten in: Artery research - Amsterdam : Atlantis Press, 2006, 2(2008), 3 vom: Aug., Seite 112-112
Übergeordnetes Werk:	volume:2 ; year:2008 ; number:3 ; month:08 ; pages:112-112

Links:	Volltext

DOI / URN:	10.1016/j.artres.2008.08.390

Katalog-ID:	SPR054917379

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100	1		\|a Leguy, C. A. D. \|e verfasserin \|4 aut
245	1	0	\|a P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model
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520			\|a Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties.
700	1		\|a Boutouyrie, P. \|4 aut
700	1		\|a Bosboom, E. M. H. \|4 aut
700	1		\|a Bozec, E. \|4 aut
700	1		\|a Simons, L. \|4 aut
700	1		\|a Hoeks, A. P. G. \|4 aut
700	1		\|a Vosse, F. N. \|4 aut
773	0	8	\|i Enthalten in \|t Artery research \|d Amsterdam : Atlantis Press, 2006 \|g 2(2008), 3 vom: Aug., Seite 112-112 \|w (DE-627)534057489 \|w (DE-600)2364789-9 \|x 1876-4401 \|7 nnns
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allfields	10.1016/j.artres.2008.08.390 doi (DE-627)SPR054917379 (SPR)j.artres.2008.08.390-e DE-627 ger DE-627 rakwb eng Leguy, C. A. D. verfasserin aut P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Published by Elsevier. All rights reserved 2008 Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties. Boutouyrie, P. aut Bosboom, E. M. H. aut Bozec, E. aut Simons, L. aut Hoeks, A. P. G. aut Vosse, F. N. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 2(2008), 3 vom: Aug., Seite 112-112 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:2 year:2008 number:3 month:08 pages:112-112 https://dx.doi.org/10.1016/j.artres.2008.08.390 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2008 3 08 112-112
spelling	10.1016/j.artres.2008.08.390 doi (DE-627)SPR054917379 (SPR)j.artres.2008.08.390-e DE-627 ger DE-627 rakwb eng Leguy, C. A. D. verfasserin aut P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Published by Elsevier. All rights reserved 2008 Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties. Boutouyrie, P. aut Bosboom, E. M. H. aut Bozec, E. aut Simons, L. aut Hoeks, A. P. G. aut Vosse, F. N. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 2(2008), 3 vom: Aug., Seite 112-112 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:2 year:2008 number:3 month:08 pages:112-112 https://dx.doi.org/10.1016/j.artres.2008.08.390 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2008 3 08 112-112
allfields_unstemmed	10.1016/j.artres.2008.08.390 doi (DE-627)SPR054917379 (SPR)j.artres.2008.08.390-e DE-627 ger DE-627 rakwb eng Leguy, C. A. D. verfasserin aut P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Published by Elsevier. All rights reserved 2008 Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties. Boutouyrie, P. aut Bosboom, E. M. H. aut Bozec, E. aut Simons, L. aut Hoeks, A. P. G. aut Vosse, F. N. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 2(2008), 3 vom: Aug., Seite 112-112 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:2 year:2008 number:3 month:08 pages:112-112 https://dx.doi.org/10.1016/j.artres.2008.08.390 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2008 3 08 112-112
allfieldsGer	10.1016/j.artres.2008.08.390 doi (DE-627)SPR054917379 (SPR)j.artres.2008.08.390-e DE-627 ger DE-627 rakwb eng Leguy, C. A. D. verfasserin aut P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Published by Elsevier. All rights reserved 2008 Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties. Boutouyrie, P. aut Bosboom, E. M. H. aut Bozec, E. aut Simons, L. aut Hoeks, A. P. G. aut Vosse, F. N. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 2(2008), 3 vom: Aug., Seite 112-112 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:2 year:2008 number:3 month:08 pages:112-112 https://dx.doi.org/10.1016/j.artres.2008.08.390 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2008 3 08 112-112
allfieldsSound	10.1016/j.artres.2008.08.390 doi (DE-627)SPR054917379 (SPR)j.artres.2008.08.390-e DE-627 ger DE-627 rakwb eng Leguy, C. A. D. verfasserin aut P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Published by Elsevier. All rights reserved 2008 Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties. Boutouyrie, P. aut Bosboom, E. M. H. aut Bozec, E. aut Simons, L. aut Hoeks, A. P. G. aut Vosse, F. N. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 2(2008), 3 vom: Aug., Seite 112-112 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:2 year:2008 number:3 month:08 pages:112-112 https://dx.doi.org/10.1016/j.artres.2008.08.390 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2008 3 08 112-112
language	English
source	Enthalten in Artery research 2(2008), 3 vom: Aug., Seite 112-112 volume:2 year:2008 number:3 month:08 pages:112-112
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A. D.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2008</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Published by Elsevier. All rights reserved 2008</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Boutouyrie, P.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bosboom, E. M. 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author	Leguy, C. A. D.
spellingShingle	Leguy, C. A. D. P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model
authorStr	Leguy, C. A. D.
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topic_title	P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model
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title	P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model
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title_full	P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model
author_sort	Leguy, C. A. D.
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author_browse	Leguy, C. A. D. Boutouyrie, P. Bosboom, E. M. H. Bozec, E. Simons, L. Hoeks, A. P. G. Vosse, F. N.
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format_se	Elektronische Aufsätze
author-letter	Leguy, C. A. D.
doi_str_mv	10.1016/j.artres.2008.08.390
title_sort	p2.24 estimation of arterial mechanical properties based on a patient specific wave propagation model
title_auth	P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model
abstract	Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties. © Published by Elsevier. All rights reserved 2008
abstractGer	Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties. © Published by Elsevier. All rights reserved 2008
abstract_unstemmed	Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties. © Published by Elsevier. All rights reserved 2008
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
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title_short	P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model
url	https://dx.doi.org/10.1016/j.artres.2008.08.390
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author2	Boutouyrie, P. Bosboom, E. M. H. Bozec, E. Simons, L. Hoeks, A. P. G. Vosse, F. N.
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doi_str	10.1016/j.artres.2008.08.390
up_date	2024-07-04T03:30:11.815Z
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All rights reserved 2008</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Arterial stiffness can be assessed using pulse wave velocity (PWV). However, distance measurement introduces an error and an average PWV is considered although arterial stiffness increases distally. A patient specific one-dimensional wave propagation model may reveal details of pressure wave propagation phenomena and mechanical properties of arteries. Methods For 6 healthy volunteers, ultrasound wall distension (WD), blood pressure (BP) waveform and blood velocity were assessed at 5 positions along the leg. Blood volume flow (BVF) for each position was estimated assuming Womersley profile. The Young’s moduli and diameters of the arteries were derived from the BP and WD. The BVF at the iliac artery (IA) is used as input for the simulations. The in-vivo results were compared with simulated BVF and BP curves to adapt the model parameters iteratively. Results The group average diameter equals 7.4±0.6 for the IA, 1.9±0.8 for the posterior tibial (PTA) and 1.7±0.5mm for the pedal (PDA) artery. The ratio IMT/diameter increases along the arterial tree, from 7.5% to 21.1% and 27.5% in the IA, PDA and PTA, respectively. The distensibility equals 0.39±0.07 and 0.36±0.$ 09MPa^{-1} $ at the IA and PDA; the PWV over IA to PDA segment is 7.4±1.0m/s. The distensibility resulting from the iterative method is 20% smaller than the first estimate based on the measurements while the PWV was the same. Conclusion The results show that the shape of simulated BVF is comparable with in-vivo estimations and that the wave propagation model can be used to estimate more accurately arterial mechanical properties.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Boutouyrie, P.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bosboom, E. M. 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P2.24 Estimation of Arterial Mechanical Properties Based on a Patient Specific Wave Propagation Model

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