Cardiovascular Aging: Insights From Magnetic Resonance Imaging
Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently bee...
Ausführliche Beschreibung
Autor*in: |
Redheuil, Alban [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2013 |
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Anmerkung: |
© Atlantis Press 2013 |
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Übergeordnetes Werk: |
Enthalten in: Artery research - Amsterdam : Atlantis Press, 2006, 7(2013), 3-4 vom: Sept., Seite 109-109 |
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Übergeordnetes Werk: |
volume:7 ; year:2013 ; number:3-4 ; month:09 ; pages:109-109 |
Links: |
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DOI / URN: |
10.1016/j.artres.2013.10.384 |
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Katalog-ID: |
SPR055018602 |
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520 | |a Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. | ||
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10.1016/j.artres.2013.10.384 doi (DE-627)SPR055018602 (SPR)j.artres.2013.10.384-e DE-627 ger DE-627 rakwb eng Redheuil, Alban verfasserin aut Cardiovascular Aging: Insights From Magnetic Resonance Imaging 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 109-109 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:109-109 https://dx.doi.org/10.1016/j.artres.2013.10.384 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 109-109 |
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10.1016/j.artres.2013.10.384 doi (DE-627)SPR055018602 (SPR)j.artres.2013.10.384-e DE-627 ger DE-627 rakwb eng Redheuil, Alban verfasserin aut Cardiovascular Aging: Insights From Magnetic Resonance Imaging 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 109-109 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:109-109 https://dx.doi.org/10.1016/j.artres.2013.10.384 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 109-109 |
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10.1016/j.artres.2013.10.384 doi (DE-627)SPR055018602 (SPR)j.artres.2013.10.384-e DE-627 ger DE-627 rakwb eng Redheuil, Alban verfasserin aut Cardiovascular Aging: Insights From Magnetic Resonance Imaging 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 109-109 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:109-109 https://dx.doi.org/10.1016/j.artres.2013.10.384 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 109-109 |
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10.1016/j.artres.2013.10.384 doi (DE-627)SPR055018602 (SPR)j.artres.2013.10.384-e DE-627 ger DE-627 rakwb eng Redheuil, Alban verfasserin aut Cardiovascular Aging: Insights From Magnetic Resonance Imaging 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 109-109 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:109-109 https://dx.doi.org/10.1016/j.artres.2013.10.384 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 109-109 |
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10.1016/j.artres.2013.10.384 doi (DE-627)SPR055018602 (SPR)j.artres.2013.10.384-e DE-627 ger DE-627 rakwb eng Redheuil, Alban verfasserin aut Cardiovascular Aging: Insights From Magnetic Resonance Imaging 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 109-109 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:109-109 https://dx.doi.org/10.1016/j.artres.2013.10.384 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 109-109 |
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Cardiovascular Aging: Insights From Magnetic Resonance Imaging |
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Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. © Atlantis Press 2013 |
abstractGer |
Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. © Atlantis Press 2013 |
abstract_unstemmed |
Abstract Aortic stiffness is now established as an independent marker of cardiovascular aging and cardiovascular risk. However, the specific role of the proximal aorta, specifically the ascending aorta, remains understudied. Magnetic resonance imaging (MRI), a non invasive technique has recently been proposed to measure new local and regional stiffness indices in the thoracic aorta. We will here review the available data on aortic stiffness assessed by MRI. We will discuss the methodological advantages and challenges of MRI, combined with applanation tonometry,to evaluate local aortic distensibility and pulse wave velocity (PWV) and summarize available results concerning the distribution of such parameters in both the general population and disease and their prognostic value. Aortic distensibility has been shown to be an early subclinical marker of vascular target organ damage in the general population and expected ranges for ascending aortic distensibility and aortic arch pulse wave velocity assessed in MRI have been described in the general population and in disease. Changes in aortic distensibility and arch PWV have been related to age-related geometric changes, specifically lengthening, enlargement and unfolding of the thoracic aorta. Increased proximal aortic stiffness measured by MRI has also been related to decreased systolic and diastolic function and concentric remodeling of the left ventricule in healthy individuals. Data are now available for proximal aortic stiffness in diabetes, hypertension and aortic diseases such as bicuspid aortic valve or Marfan syndrome. We will review data on aortic distensibility as an independent predictor of mortality and incident cardiovascular disease in the general population. © Atlantis Press 2013 |
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