P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure

Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular di...
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Autor*in:	Kukadia, S. [verfasserIn] Tillin, T. Coady, E. Chaturvedi, N. Hughes, A. D.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Anmerkung:	© Atlantis Press 2013

Übergeordnetes Werk:	Enthalten in: Artery research - Amsterdam : Atlantis Press, 2006, 7(2013), 3-4 vom: Sept., Seite 142-142
Übergeordnetes Werk:	volume:7 ; year:2013 ; number:3-4 ; month:09 ; pages:142-142

Links:	Volltext

DOI / URN:	10.1016/j.artres.2013.10.142

Katalog-ID:	SPR055018882

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520			\|a Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability.
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700	1		\|a Hughes, A. D. \|4 aut
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allfields	10.1016/j.artres.2013.10.142 doi (DE-627)SPR055018882 (SPR)j.artres.2013.10.142-e DE-627 ger DE-627 rakwb eng Kukadia, S. verfasserin aut P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability. Tillin, T. aut Coady, E. aut Chaturvedi, N. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 142-142 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:142-142 https://dx.doi.org/10.1016/j.artres.2013.10.142 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 142-142
spelling	10.1016/j.artres.2013.10.142 doi (DE-627)SPR055018882 (SPR)j.artres.2013.10.142-e DE-627 ger DE-627 rakwb eng Kukadia, S. verfasserin aut P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability. Tillin, T. aut Coady, E. aut Chaturvedi, N. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 142-142 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:142-142 https://dx.doi.org/10.1016/j.artres.2013.10.142 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 142-142
allfields_unstemmed	10.1016/j.artres.2013.10.142 doi (DE-627)SPR055018882 (SPR)j.artres.2013.10.142-e DE-627 ger DE-627 rakwb eng Kukadia, S. verfasserin aut P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability. Tillin, T. aut Coady, E. aut Chaturvedi, N. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 142-142 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:142-142 https://dx.doi.org/10.1016/j.artres.2013.10.142 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 142-142
allfieldsGer	10.1016/j.artres.2013.10.142 doi (DE-627)SPR055018882 (SPR)j.artres.2013.10.142-e DE-627 ger DE-627 rakwb eng Kukadia, S. verfasserin aut P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability. Tillin, T. aut Coady, E. aut Chaturvedi, N. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 142-142 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:142-142 https://dx.doi.org/10.1016/j.artres.2013.10.142 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 142-142
allfieldsSound	10.1016/j.artres.2013.10.142 doi (DE-627)SPR055018882 (SPR)j.artres.2013.10.142-e DE-627 ger DE-627 rakwb eng Kukadia, S. verfasserin aut P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability. Tillin, T. aut Coady, E. aut Chaturvedi, N. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 142-142 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:142-142 https://dx.doi.org/10.1016/j.artres.2013.10.142 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 142-142
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Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. 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author	Kukadia, S.
spellingShingle	Kukadia, S. P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure
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title_sort	p4.24: dietary inorganic nitrate lowers central blood pressure
title_auth	P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure
abstract	Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability. © Atlantis Press 2013
abstractGer	Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability. © Atlantis Press 2013
abstract_unstemmed	Background Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. Beetroot juice could have a role in CV risk management in the general population, but further research is required to establish its long-term benefits, safety and tolerability. © Atlantis Press 2013
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Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The effect on aortic (central) BP, which may be a better predictor of cardiovascular disease, has not been studied. Objectives To measure the effect of dietary nitrate in beetroot juice on central BP at both 30 minutes and over a 6 hour period post-beetroot juice consumption. Method A double-blind, randomised, placebo-controlled crossover trial was performed in nine healthy, normotensive men and women aged between 22 and 45 years. Participants were randomised to receive beetroot juice (6.5-7.3 mmol nitrate) or placebo juice (0.04-0.06 mmol nitrate). Brachial and central BP were measured at baseline, 30 and 60 minutes post-ingestion, and at least hourly for the following 24 hours. Following a washout period, the procedure was repeated within seven days with crossover to the opposite arm of the trial. There were no dietary restrictions during the study. Results Compared with placebo, beetroot juice lowered central systolic BP at 30 minutes (change in beetroot juice: -2.6±3.4 mmHg vs. change in placebo: 1.8±5.9 mmHg, P = 0.045). Beetroot juice also lowered central systolic BP averaged over 6 hours post-ingestion (beetroot: 106±8 mmHg vs. placebo: 111±11 mmHg, P = 0.029). Conclusion Consumption of beetroot juice lowered central BP. 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