P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population

Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethni...
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Autor*in:	Lau, W. R. [verfasserIn] Park, C. M. Hughes, A. D.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Anmerkung:	© Atlantis Press 2013

Übergeordnetes Werk:	Enthalten in: Artery research - Amsterdam : Atlantis Press, 2006, 7(2013), 3-4 vom: Sept., Seite 125-125
Übergeordnetes Werk:	volume:7 ; year:2013 ; number:3-4 ; month:09 ; pages:125-125

Links:	Volltext

DOI / URN:	10.1016/j.artres.2013.10.084

Katalog-ID:	SPR055020380

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520			\|a Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’.
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allfields	10.1016/j.artres.2013.10.084 doi (DE-627)SPR055020380 (SPR)j.artres.2013.10.084-e DE-627 ger DE-627 rakwb eng Lau, W. R. verfasserin aut P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’. Park, C. M. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 125-125 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:125-125 https://dx.doi.org/10.1016/j.artres.2013.10.084 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 125-125
spelling	10.1016/j.artres.2013.10.084 doi (DE-627)SPR055020380 (SPR)j.artres.2013.10.084-e DE-627 ger DE-627 rakwb eng Lau, W. R. verfasserin aut P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’. Park, C. M. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 125-125 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:125-125 https://dx.doi.org/10.1016/j.artres.2013.10.084 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 125-125
allfields_unstemmed	10.1016/j.artres.2013.10.084 doi (DE-627)SPR055020380 (SPR)j.artres.2013.10.084-e DE-627 ger DE-627 rakwb eng Lau, W. R. verfasserin aut P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’. Park, C. M. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 125-125 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:125-125 https://dx.doi.org/10.1016/j.artres.2013.10.084 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 125-125
allfieldsGer	10.1016/j.artres.2013.10.084 doi (DE-627)SPR055020380 (SPR)j.artres.2013.10.084-e DE-627 ger DE-627 rakwb eng Lau, W. R. verfasserin aut P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’. Park, C. M. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 125-125 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:125-125 https://dx.doi.org/10.1016/j.artres.2013.10.084 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 125-125
allfieldsSound	10.1016/j.artres.2013.10.084 doi (DE-627)SPR055020380 (SPR)j.artres.2013.10.084-e DE-627 ger DE-627 rakwb eng Lau, W. R. verfasserin aut P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Atlantis Press 2013 Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’. Park, C. M. aut Hughes, A. D. aut Enthalten in Artery research Amsterdam : Atlantis Press, 2006 7(2013), 3-4 vom: Sept., Seite 125-125 (DE-627)534057489 (DE-600)2364789-9 1876-4401 nnns volume:7 year:2013 number:3-4 month:09 pages:125-125 https://dx.doi.org/10.1016/j.artres.2013.10.084 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2013 3-4 09 125-125
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R.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2013</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Atlantis Press 2013</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Park, C. 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author	Lau, W. R.
spellingShingle	Lau, W. R. P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population
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topic_title	P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population
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title	P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population
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title_full	P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population
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author_browse	Lau, W. R. Park, C. M. Hughes, A. D.
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author-letter	Lau, W. R.
doi_str_mv	10.1016/j.artres.2013.10.084
title_sort	p2.23: assessing myocardial function using speckle-tracking echocardiography in an older population
title_auth	P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population
abstract	Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’. © Atlantis Press 2013
abstractGer	Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’. © Atlantis Press 2013
abstract_unstemmed	Background Left ventricular systolic dysfunction, an independent predictor of heart failure (HF) and cardiovascular mortality, may be worse in South Asians and African-Caribbeans (than Europeans) as they have more adverse cardiovascular risk factor profiles. Objectives We sought to investigate ethnic differences in speckle-tracking echocardiography (STE)-derived strain (ε) and strain rate (SR) in a community-based cohort of European, South Asian and African-Caribbean older men, and the role of CVD risk factors in accounting for these differences. Methods and results We recruited 339 men (113 from each ethnic group) with echocardiographic data from the Southall and Brent REvisited (SABRE) cohort, and measured peak systolic longitudinal sand SR. Anthropometric, haemody-namic, fasting blood and conventional and tissue Doppler echocardiographic data were also collected. There were no significant differences in peak systolic longitudinal ε between Europeans (mean±SD, -17.7±3.1%), South Asians (-16.9±2.9%) and African-Caribbeans (-17.1 ±3.0%) (p = 0.200). Peak systolic longitudinal SR also showed no significant ethnic variation (Europeans: -0.50±0.$ 12s^{−1} $, South Asians: -0.48±0.$ 10s^{−1} $, African-Caribbeans: -0.47±0.$ 11s^{−1} $, p = 0.198). Age-adjusted peak systolic longitudinal SR and (tissue Doppler-derived) peak systolic myocardial velocity (s’) were compared in subjects with and without hypertension, coronary heart disease (CHD) and diabetes mellitus. Subjects with hypertension and CHD had an attenuated SR and s’ compared to those without, but diabetes mellitus was associated with a lower s’ only. P-values were more significant for s’ than SR. Conclusions There were no significant ethnic differences in longitudinal ε & SR. SR could detect myocardial dysfunction in subjects with CHD and hypertension, but was inferior to s’. © Atlantis Press 2013
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title_short	P2.23: Assessing Myocardial Function Using Speckle-Tracking Echocardiography in an Older Population
url	https://dx.doi.org/10.1016/j.artres.2013.10.084
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up_date	2024-07-04T03:52:46.880Z
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