Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study

Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite thi...
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Autor*in:	Guerzoni, Simona [verfasserIn] Castro, Flavia Lo Brovia, Daria Baraldi, Carlo Pani, Luca

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Migraine Fremanezumab Galcanezumab Erenumab Blood pressure

Anmerkung:	© Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Übergeordnetes Werk:	Enthalten in: Neurological sciences - Springer International Publishing, 2000, 45(2023), 4 vom: 06. Nov., Seite 1661-1668
Übergeordnetes Werk:	volume:45 ; year:2023 ; number:4 ; day:06 ; month:11 ; pages:1661-1668

Links:	Volltext

DOI / URN:	10.1007/s10072-023-07167-z

Katalog-ID:	SPR055165435

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allfields	10.1007/s10072-023-07167-z doi (DE-627)SPR055165435 (SPR)s10072-023-07167-z-e DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.90 bkl Guerzoni, Simona verfasserin aut Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. Anyway, patients with a pre-existing hypertension should be cautiously monitored because they are more likely to develop hypertension. Migraine (dpeaa)DE-He213 Fremanezumab (dpeaa)DE-He213 Galcanezumab (dpeaa)DE-He213 Erenumab (dpeaa)DE-He213 Blood pressure (dpeaa)DE-He213 Castro, Flavia Lo (orcid)0000-0002-8572-3421 aut Brovia, Daria aut Baraldi, Carlo aut Pani, Luca aut Enthalten in Neurological sciences Springer International Publishing, 2000 45(2023), 4 vom: 06. Nov., Seite 1661-1668 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:45 year:2023 number:4 day:06 month:11 pages:1661-1668 https://dx.doi.org/10.1007/s10072-023-07167-z lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 VZ AR 45 2023 4 06 11 1661-1668
spelling	10.1007/s10072-023-07167-z doi (DE-627)SPR055165435 (SPR)s10072-023-07167-z-e DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.90 bkl Guerzoni, Simona verfasserin aut Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. Anyway, patients with a pre-existing hypertension should be cautiously monitored because they are more likely to develop hypertension. Migraine (dpeaa)DE-He213 Fremanezumab (dpeaa)DE-He213 Galcanezumab (dpeaa)DE-He213 Erenumab (dpeaa)DE-He213 Blood pressure (dpeaa)DE-He213 Castro, Flavia Lo (orcid)0000-0002-8572-3421 aut Brovia, Daria aut Baraldi, Carlo aut Pani, Luca aut Enthalten in Neurological sciences Springer International Publishing, 2000 45(2023), 4 vom: 06. Nov., Seite 1661-1668 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:45 year:2023 number:4 day:06 month:11 pages:1661-1668 https://dx.doi.org/10.1007/s10072-023-07167-z lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 VZ AR 45 2023 4 06 11 1661-1668
allfields_unstemmed	10.1007/s10072-023-07167-z doi (DE-627)SPR055165435 (SPR)s10072-023-07167-z-e DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.90 bkl Guerzoni, Simona verfasserin aut Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. Anyway, patients with a pre-existing hypertension should be cautiously monitored because they are more likely to develop hypertension. Migraine (dpeaa)DE-He213 Fremanezumab (dpeaa)DE-He213 Galcanezumab (dpeaa)DE-He213 Erenumab (dpeaa)DE-He213 Blood pressure (dpeaa)DE-He213 Castro, Flavia Lo (orcid)0000-0002-8572-3421 aut Brovia, Daria aut Baraldi, Carlo aut Pani, Luca aut Enthalten in Neurological sciences Springer International Publishing, 2000 45(2023), 4 vom: 06. Nov., Seite 1661-1668 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:45 year:2023 number:4 day:06 month:11 pages:1661-1668 https://dx.doi.org/10.1007/s10072-023-07167-z lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 VZ AR 45 2023 4 06 11 1661-1668
allfieldsGer	10.1007/s10072-023-07167-z doi (DE-627)SPR055165435 (SPR)s10072-023-07167-z-e DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.90 bkl Guerzoni, Simona verfasserin aut Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. Anyway, patients with a pre-existing hypertension should be cautiously monitored because they are more likely to develop hypertension. Migraine (dpeaa)DE-He213 Fremanezumab (dpeaa)DE-He213 Galcanezumab (dpeaa)DE-He213 Erenumab (dpeaa)DE-He213 Blood pressure (dpeaa)DE-He213 Castro, Flavia Lo (orcid)0000-0002-8572-3421 aut Brovia, Daria aut Baraldi, Carlo aut Pani, Luca aut Enthalten in Neurological sciences Springer International Publishing, 2000 45(2023), 4 vom: 06. Nov., Seite 1661-1668 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:45 year:2023 number:4 day:06 month:11 pages:1661-1668 https://dx.doi.org/10.1007/s10072-023-07167-z lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 VZ AR 45 2023 4 06 11 1661-1668
allfieldsSound	10.1007/s10072-023-07167-z doi (DE-627)SPR055165435 (SPR)s10072-023-07167-z-e DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.90 bkl Guerzoni, Simona verfasserin aut Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. Anyway, patients with a pre-existing hypertension should be cautiously monitored because they are more likely to develop hypertension. Migraine (dpeaa)DE-He213 Fremanezumab (dpeaa)DE-He213 Galcanezumab (dpeaa)DE-He213 Erenumab (dpeaa)DE-He213 Blood pressure (dpeaa)DE-He213 Castro, Flavia Lo (orcid)0000-0002-8572-3421 aut Brovia, Daria aut Baraldi, Carlo aut Pani, Luca aut Enthalten in Neurological sciences Springer International Publishing, 2000 45(2023), 4 vom: 06. Nov., Seite 1661-1668 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:45 year:2023 number:4 day:06 month:11 pages:1661-1668 https://dx.doi.org/10.1007/s10072-023-07167-z lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 VZ AR 45 2023 4 06 11 1661-1668
language	English
source	Enthalten in Neurological sciences 45(2023), 4 vom: 06. Nov., Seite 1661-1668 volume:45 year:2023 number:4 day:06 month:11 pages:1661-1668
sourceStr	Enthalten in Neurological sciences 45(2023), 4 vom: 06. Nov., Seite 1661-1668 volume:45 year:2023 number:4 day:06 month:11 pages:1661-1668
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Migraine Fremanezumab Galcanezumab Erenumab Blood pressure
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container_title	Neurological sciences
authorswithroles_txt_mv	Guerzoni, Simona @@aut@@ Castro, Flavia Lo @@aut@@ Brovia, Daria @@aut@@ Baraldi, Carlo @@aut@@ Pani, Luca @@aut@@
publishDateDaySort_date	2023-11-06T00:00:00Z
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author	Guerzoni, Simona
spellingShingle	Guerzoni, Simona ddc 610 bkl 44.90 misc Migraine misc Fremanezumab misc Galcanezumab misc Erenumab misc Blood pressure Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study
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topic_title	610 VZ 44.90 bkl Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study Migraine (dpeaa)DE-He213 Fremanezumab (dpeaa)DE-He213 Galcanezumab (dpeaa)DE-He213 Erenumab (dpeaa)DE-He213 Blood pressure (dpeaa)DE-He213
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title	Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study
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title_full	Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study
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author_browse	Guerzoni, Simona Castro, Flavia Lo Brovia, Daria Baraldi, Carlo Pani, Luca
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title_sort	evaluation of the risk of hypertension in patients treated with anti-cgrp monoclonal antibodies in a real-life study
title_auth	Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study
abstract	Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. Anyway, patients with a pre-existing hypertension should be cautiously monitored because they are more likely to develop hypertension. © Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
abstractGer	Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. Anyway, patients with a pre-existing hypertension should be cautiously monitored because they are more likely to develop hypertension. © Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
abstract_unstemmed	Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. Anyway, patients with a pre-existing hypertension should be cautiously monitored because they are more likely to develop hypertension. © Fondazione Società Italiana di Neurologia 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
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title_short	Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study
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Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective To explore the rate of hypertension incoming in patients treated with monoclonal antibodies against the calcitonin gene-related peptide. Background The monoclonal antibodies blocking the calcitonin gene-related peptide are unquestionable effective in the prevention of migraine. Despite this, the development of hypertension has been detected in some patients. Methods This was a retrospective study conducted at the University Hospital of Modena. Patients were visited quarterly up to 1 year. Results Globally, no significant increase in the blood pressure was detected. The 5.7% of the patients developed a significant increase in their blood pressure. In particular, patients with a pre-existing hypertension were more likely to have a significant increase in the blood pressure. Conclusion The risk of developing hypertension during a treatment with anti-calcitonin gene-related peptide monoclonal antibodies seems low. 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Evaluation of the risk of hypertension in patients treated with anti-CGRP monoclonal antibodies in a real-life study

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