Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy

Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Gołuch, Małgorzata [verfasserIn] Pytlewska, Agnieszka Sarnecki, Jędrzej Chodnicka, Paulina Śliwińska, Anna Obrycki, Łukasz Jurkiewicz, Elżbieta

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	Magnetic resonance urography Differential renal function Dynamic renal scintigraphy Pelvicalyceal dilatation CAKUT Pediatric urology Urinary system Functional imaging

Anmerkung:	© The Author(s) 2024

Übergeordnetes Werk:	Enthalten in: BMC pediatrics - BioMed Central, 2001, 24(2024), 1 vom: 25. März
Übergeordnetes Werk:	volume:24 ; year:2024 ; number:1 ; day:25 ; month:03

Links:	Volltext

DOI / URN:	10.1186/s12887-024-04694-2

Katalog-ID:	SPR055294235

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520			\|a Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children.
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allfields	10.1186/s12887-024-04694-2 doi (DE-627)SPR055294235 (SPR)s12887-024-04694-2-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Gołuch, Małgorzata verfasserin aut Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. Magnetic resonance urography (dpeaa)DE-He213 Differential renal function (dpeaa)DE-He213 Dynamic renal scintigraphy (dpeaa)DE-He213 Pelvicalyceal dilatation (dpeaa)DE-He213 CAKUT (dpeaa)DE-He213 Pediatric urology (dpeaa)DE-He213 Urinary system (dpeaa)DE-He213 Functional imaging (dpeaa)DE-He213 Pytlewska, Agnieszka aut Sarnecki, Jędrzej aut Chodnicka, Paulina aut Śliwińska, Anna aut Obrycki, Łukasz aut Jurkiewicz, Elżbieta aut Enthalten in BMC pediatrics BioMed Central, 2001 24(2024), 1 vom: 25. März (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:24 year:2024 number:1 day:25 month:03 https://dx.doi.org/10.1186/s12887-024-04694-2 kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 25 03
spelling	10.1186/s12887-024-04694-2 doi (DE-627)SPR055294235 (SPR)s12887-024-04694-2-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Gołuch, Małgorzata verfasserin aut Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. Magnetic resonance urography (dpeaa)DE-He213 Differential renal function (dpeaa)DE-He213 Dynamic renal scintigraphy (dpeaa)DE-He213 Pelvicalyceal dilatation (dpeaa)DE-He213 CAKUT (dpeaa)DE-He213 Pediatric urology (dpeaa)DE-He213 Urinary system (dpeaa)DE-He213 Functional imaging (dpeaa)DE-He213 Pytlewska, Agnieszka aut Sarnecki, Jędrzej aut Chodnicka, Paulina aut Śliwińska, Anna aut Obrycki, Łukasz aut Jurkiewicz, Elżbieta aut Enthalten in BMC pediatrics BioMed Central, 2001 24(2024), 1 vom: 25. März (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:24 year:2024 number:1 day:25 month:03 https://dx.doi.org/10.1186/s12887-024-04694-2 kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 25 03
allfields_unstemmed	10.1186/s12887-024-04694-2 doi (DE-627)SPR055294235 (SPR)s12887-024-04694-2-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Gołuch, Małgorzata verfasserin aut Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. Magnetic resonance urography (dpeaa)DE-He213 Differential renal function (dpeaa)DE-He213 Dynamic renal scintigraphy (dpeaa)DE-He213 Pelvicalyceal dilatation (dpeaa)DE-He213 CAKUT (dpeaa)DE-He213 Pediatric urology (dpeaa)DE-He213 Urinary system (dpeaa)DE-He213 Functional imaging (dpeaa)DE-He213 Pytlewska, Agnieszka aut Sarnecki, Jędrzej aut Chodnicka, Paulina aut Śliwińska, Anna aut Obrycki, Łukasz aut Jurkiewicz, Elżbieta aut Enthalten in BMC pediatrics BioMed Central, 2001 24(2024), 1 vom: 25. März (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:24 year:2024 number:1 day:25 month:03 https://dx.doi.org/10.1186/s12887-024-04694-2 kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 25 03
allfieldsGer	10.1186/s12887-024-04694-2 doi (DE-627)SPR055294235 (SPR)s12887-024-04694-2-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Gołuch, Małgorzata verfasserin aut Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. Magnetic resonance urography (dpeaa)DE-He213 Differential renal function (dpeaa)DE-He213 Dynamic renal scintigraphy (dpeaa)DE-He213 Pelvicalyceal dilatation (dpeaa)DE-He213 CAKUT (dpeaa)DE-He213 Pediatric urology (dpeaa)DE-He213 Urinary system (dpeaa)DE-He213 Functional imaging (dpeaa)DE-He213 Pytlewska, Agnieszka aut Sarnecki, Jędrzej aut Chodnicka, Paulina aut Śliwińska, Anna aut Obrycki, Łukasz aut Jurkiewicz, Elżbieta aut Enthalten in BMC pediatrics BioMed Central, 2001 24(2024), 1 vom: 25. März (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:24 year:2024 number:1 day:25 month:03 https://dx.doi.org/10.1186/s12887-024-04694-2 kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 25 03
allfieldsSound	10.1186/s12887-024-04694-2 doi (DE-627)SPR055294235 (SPR)s12887-024-04694-2-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Gołuch, Małgorzata verfasserin aut Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. Magnetic resonance urography (dpeaa)DE-He213 Differential renal function (dpeaa)DE-He213 Dynamic renal scintigraphy (dpeaa)DE-He213 Pelvicalyceal dilatation (dpeaa)DE-He213 CAKUT (dpeaa)DE-He213 Pediatric urology (dpeaa)DE-He213 Urinary system (dpeaa)DE-He213 Functional imaging (dpeaa)DE-He213 Pytlewska, Agnieszka aut Sarnecki, Jędrzej aut Chodnicka, Paulina aut Śliwińska, Anna aut Obrycki, Łukasz aut Jurkiewicz, Elżbieta aut Enthalten in BMC pediatrics BioMed Central, 2001 24(2024), 1 vom: 25. März (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:24 year:2024 number:1 day:25 month:03 https://dx.doi.org/10.1186/s12887-024-04694-2 kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 25 03
language	English
source	Enthalten in BMC pediatrics 24(2024), 1 vom: 25. März volume:24 year:2024 number:1 day:25 month:03
sourceStr	Enthalten in BMC pediatrics 24(2024), 1 vom: 25. März volume:24 year:2024 number:1 day:25 month:03
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Magnetic resonance urography Differential renal function Dynamic renal scintigraphy Pelvicalyceal dilatation CAKUT Pediatric urology Urinary system Functional imaging
dewey-raw	610
isfreeaccess_bool	true
container_title	BMC pediatrics
authorswithroles_txt_mv	Gołuch, Małgorzata @@aut@@ Pytlewska, Agnieszka @@aut@@ Sarnecki, Jędrzej @@aut@@ Chodnicka, Paulina @@aut@@ Śliwińska, Anna @@aut@@ Obrycki, Łukasz @@aut@@ Jurkiewicz, Elżbieta @@aut@@
publishDateDaySort_date	2024-03-25T00:00:00Z
hierarchy_top_id	326643621
dewey-sort	3610
id	SPR055294235
language_de	englisch
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The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. 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author	Gołuch, Małgorzata
spellingShingle	Gołuch, Małgorzata ddc 610 bkl 44.00 misc Magnetic resonance urography misc Differential renal function misc Dynamic renal scintigraphy misc Pelvicalyceal dilatation misc CAKUT misc Pediatric urology misc Urinary system misc Functional imaging Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy
authorStr	Gołuch, Małgorzata
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topic_title	610 VZ 44.00 bkl Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy Magnetic resonance urography (dpeaa)DE-He213 Differential renal function (dpeaa)DE-He213 Dynamic renal scintigraphy (dpeaa)DE-He213 Pelvicalyceal dilatation (dpeaa)DE-He213 CAKUT (dpeaa)DE-He213 Pediatric urology (dpeaa)DE-He213 Urinary system (dpeaa)DE-He213 Functional imaging (dpeaa)DE-He213
topic	ddc 610 bkl 44.00 misc Magnetic resonance urography misc Differential renal function misc Dynamic renal scintigraphy misc Pelvicalyceal dilatation misc CAKUT misc Pediatric urology misc Urinary system misc Functional imaging
topic_unstemmed	ddc 610 bkl 44.00 misc Magnetic resonance urography misc Differential renal function misc Dynamic renal scintigraphy misc Pelvicalyceal dilatation misc CAKUT misc Pediatric urology misc Urinary system misc Functional imaging
topic_browse	ddc 610 bkl 44.00 misc Magnetic resonance urography misc Differential renal function misc Dynamic renal scintigraphy misc Pelvicalyceal dilatation misc CAKUT misc Pediatric urology misc Urinary system misc Functional imaging
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title	Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy
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title_full	Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy
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author_browse	Gołuch, Małgorzata Pytlewska, Agnieszka Sarnecki, Jędrzej Chodnicka, Paulina Śliwińska, Anna Obrycki, Łukasz Jurkiewicz, Elżbieta
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title_sort	evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy
title_auth	Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy
abstract	Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. © The Author(s) 2024
abstractGer	Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. © The Author(s) 2024
abstract_unstemmed	Background Urinary system anomalies, both congenital and acquired, constitute a relatively common clinical problem in children. The main role of diagnostic imaging is to determine early diagnosis and support therapeutic decisions to prevent the development of chronic renal disease. The aim of this study was to evaluate the utility of magnetic resonance urography (MRU) in assessment of urinary system in children, by comparing differential renal function calculated using MRU with dynamic renal scintigraphy (DRS). Materials and methods The study group consisted of 46 patients aged 1 week to 17 years (median 7 (0.5; 13) years, 17 (37%) girls, 29 (63%) boys), who underwent dynamic renal scintigraphy due to various clinical reasons. All participants underwent MRU, which was used to measure differential renal function. Functional analysis was performed using dedicated external software (CHOP-fMRU and pMRI without prior knowledge of DRS results. MRU results acquired using pMRI were assessed for inter and intraobserver agreement. Results Statistical analysis of the results showed excellent agreement between MRU and DRS in measuring differential renal function with Pearson correlation coefficient 0.987 for CHOP-fMRU and 0.971 for pMRI, p < 0.001. Interclass correlation coefficient (ICC) for these programs was 0.987 (95% CI 0.976–0.993) and 0.969 (95% CI 0.945–0.983) respectively, p < 0.001. The Bland-Altman 95% limits of agreement for CHOP-fMRU results vs. DRS was − 6.29–5.50 p.p. and for pMRI results vs. DRS − 9.15–9.63 p.p. The differential renal function measurements calculated in pMRI showed excellent intraobserver and interobserver agreement with ICC 0.996 (95% CI 0.994–0.998) and 0.992 (95% CI 0.986–0.996) respectively, p < 0.001. Conclusions The study showed no significant differences between magnetic resonance urography and dynamic renal scintigraphy in calculating differential renal function. It indicates high utility of MRU in the evaluation of urinary system in children. © The Author(s) 2024
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title_short	Evaluation of differential renal function in children – a comparative study between magnetic resonance urography and dynamic renal scintigraphy
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author2	Pytlewska, Agnieszka Sarnecki, Jędrzej Chodnicka, Paulina Śliwińska, Anna Obrycki, Łukasz Jurkiewicz, Elżbieta
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