Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans
Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (S...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hynes, Denise M. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Anmerkung: |
© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 |
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| Übergeordnetes Werk: |
Enthalten in: Journal of general internal medicine - Springer International Publishing, 1986, 39(2023), 4 vom: 26. Okt., Seite 626-635 |
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| Übergeordnetes Werk: |
volume:39 ; year:2023 ; number:4 ; day:26 ; month:10 ; pages:626-635 |
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| DOI / URN: |
10.1007/s11606-023-08440-9 |
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| Katalog-ID: |
SPR055322433 |
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| 520 | |a Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. | ||
| 700 | 1 | |a Niederhausen, Meike |4 aut | |
| 700 | 1 | |a Chen, Jason I. |4 aut | |
| 700 | 1 | |a Shahoumian, Troy A. |4 aut | |
| 700 | 1 | |a Rowneki, Mazhgan |4 aut | |
| 700 | 1 | |a Hickok, Alex |4 aut | |
| 700 | 1 | |a Shepherd-Banigan, Megan |4 aut | |
| 700 | 1 | |a Hawkins, Eric J. |4 aut | |
| 700 | 1 | |a Naylor, Jennifer |4 aut | |
| 700 | 1 | |a Teo, Alan |4 aut | |
| 700 | 1 | |a Govier, Diana J. |4 aut | |
| 700 | 1 | |a Berry, Kristin |4 aut | |
| 700 | 1 | |a McCready, Holly |4 aut | |
| 700 | 1 | |a Osborne, Thomas F. |4 aut | |
| 700 | 1 | |a Wong, Edwin |4 aut | |
| 700 | 1 | |a Hebert, Paul L. |4 aut | |
| 700 | 1 | |a Smith, Valerie A. |4 aut | |
| 700 | 1 | |a Bowling, C. Barrett |4 aut | |
| 700 | 1 | |a Boyko, Edward J. |4 aut | |
| 700 | 1 | |a Ioannou, George N. |4 aut | |
| 700 | 1 | |a Iwashyna, Theodore J. |4 aut | |
| 700 | 1 | |a Maciejewski, Matthew L. |4 aut | |
| 700 | 1 | |a O’Hare, Ann M. |4 aut | |
| 700 | 1 | |a Viglianti, Elizabeth M. |4 aut | |
| 700 | 1 | |a Bohnert, Amy S.-B. |4 aut | |
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10.1007/s11606-023-08440-9 doi (DE-627)SPR055322433 (SPR)s11606-023-08440-9-e DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Hynes, Denise M. verfasserin (orcid)0000-0002-6436-7157 aut Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. Niederhausen, Meike aut Chen, Jason I. aut Shahoumian, Troy A. aut Rowneki, Mazhgan aut Hickok, Alex aut Shepherd-Banigan, Megan aut Hawkins, Eric J. aut Naylor, Jennifer aut Teo, Alan aut Govier, Diana J. aut Berry, Kristin aut McCready, Holly aut Osborne, Thomas F. aut Wong, Edwin aut Hebert, Paul L. aut Smith, Valerie A. aut Bowling, C. Barrett aut Boyko, Edward J. aut Ioannou, George N. aut Iwashyna, Theodore J. aut Maciejewski, Matthew L. aut O’Hare, Ann M. aut Viglianti, Elizabeth M. aut Bohnert, Amy S.-B. aut Enthalten in Journal of general internal medicine Springer International Publishing, 1986 39(2023), 4 vom: 26. Okt., Seite 626-635 (DE-627)320456978 (DE-600)2006784-7 1525-1497 nnns volume:39 year:2023 number:4 day:26 month:10 pages:626-635 https://dx.doi.org/10.1007/s11606-023-08440-9 lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.61 VZ AR 39 2023 4 26 10 626-635 |
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10.1007/s11606-023-08440-9 doi (DE-627)SPR055322433 (SPR)s11606-023-08440-9-e DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Hynes, Denise M. verfasserin (orcid)0000-0002-6436-7157 aut Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. Niederhausen, Meike aut Chen, Jason I. aut Shahoumian, Troy A. aut Rowneki, Mazhgan aut Hickok, Alex aut Shepherd-Banigan, Megan aut Hawkins, Eric J. aut Naylor, Jennifer aut Teo, Alan aut Govier, Diana J. aut Berry, Kristin aut McCready, Holly aut Osborne, Thomas F. aut Wong, Edwin aut Hebert, Paul L. aut Smith, Valerie A. aut Bowling, C. Barrett aut Boyko, Edward J. aut Ioannou, George N. aut Iwashyna, Theodore J. aut Maciejewski, Matthew L. aut O’Hare, Ann M. aut Viglianti, Elizabeth M. aut Bohnert, Amy S.-B. aut Enthalten in Journal of general internal medicine Springer International Publishing, 1986 39(2023), 4 vom: 26. Okt., Seite 626-635 (DE-627)320456978 (DE-600)2006784-7 1525-1497 nnns volume:39 year:2023 number:4 day:26 month:10 pages:626-635 https://dx.doi.org/10.1007/s11606-023-08440-9 lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.61 VZ AR 39 2023 4 26 10 626-635 |
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10.1007/s11606-023-08440-9 doi (DE-627)SPR055322433 (SPR)s11606-023-08440-9-e DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Hynes, Denise M. verfasserin (orcid)0000-0002-6436-7157 aut Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. Niederhausen, Meike aut Chen, Jason I. aut Shahoumian, Troy A. aut Rowneki, Mazhgan aut Hickok, Alex aut Shepherd-Banigan, Megan aut Hawkins, Eric J. aut Naylor, Jennifer aut Teo, Alan aut Govier, Diana J. aut Berry, Kristin aut McCready, Holly aut Osborne, Thomas F. aut Wong, Edwin aut Hebert, Paul L. aut Smith, Valerie A. aut Bowling, C. Barrett aut Boyko, Edward J. aut Ioannou, George N. aut Iwashyna, Theodore J. aut Maciejewski, Matthew L. aut O’Hare, Ann M. aut Viglianti, Elizabeth M. aut Bohnert, Amy S.-B. aut Enthalten in Journal of general internal medicine Springer International Publishing, 1986 39(2023), 4 vom: 26. Okt., Seite 626-635 (DE-627)320456978 (DE-600)2006784-7 1525-1497 nnns volume:39 year:2023 number:4 day:26 month:10 pages:626-635 https://dx.doi.org/10.1007/s11606-023-08440-9 lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.61 VZ AR 39 2023 4 26 10 626-635 |
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10.1007/s11606-023-08440-9 doi (DE-627)SPR055322433 (SPR)s11606-023-08440-9-e DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Hynes, Denise M. verfasserin (orcid)0000-0002-6436-7157 aut Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. Niederhausen, Meike aut Chen, Jason I. aut Shahoumian, Troy A. aut Rowneki, Mazhgan aut Hickok, Alex aut Shepherd-Banigan, Megan aut Hawkins, Eric J. aut Naylor, Jennifer aut Teo, Alan aut Govier, Diana J. aut Berry, Kristin aut McCready, Holly aut Osborne, Thomas F. aut Wong, Edwin aut Hebert, Paul L. aut Smith, Valerie A. aut Bowling, C. Barrett aut Boyko, Edward J. aut Ioannou, George N. aut Iwashyna, Theodore J. aut Maciejewski, Matthew L. aut O’Hare, Ann M. aut Viglianti, Elizabeth M. aut Bohnert, Amy S.-B. aut Enthalten in Journal of general internal medicine Springer International Publishing, 1986 39(2023), 4 vom: 26. Okt., Seite 626-635 (DE-627)320456978 (DE-600)2006784-7 1525-1497 nnns volume:39 year:2023 number:4 day:26 month:10 pages:626-635 https://dx.doi.org/10.1007/s11606-023-08440-9 lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.61 VZ AR 39 2023 4 26 10 626-635 |
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10.1007/s11606-023-08440-9 doi (DE-627)SPR055322433 (SPR)s11606-023-08440-9-e DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Hynes, Denise M. verfasserin (orcid)0000-0002-6436-7157 aut Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. Niederhausen, Meike aut Chen, Jason I. aut Shahoumian, Troy A. aut Rowneki, Mazhgan aut Hickok, Alex aut Shepherd-Banigan, Megan aut Hawkins, Eric J. aut Naylor, Jennifer aut Teo, Alan aut Govier, Diana J. aut Berry, Kristin aut McCready, Holly aut Osborne, Thomas F. aut Wong, Edwin aut Hebert, Paul L. aut Smith, Valerie A. aut Bowling, C. Barrett aut Boyko, Edward J. aut Ioannou, George N. aut Iwashyna, Theodore J. aut Maciejewski, Matthew L. aut O’Hare, Ann M. aut Viglianti, Elizabeth M. aut Bohnert, Amy S.-B. aut Enthalten in Journal of general internal medicine Springer International Publishing, 1986 39(2023), 4 vom: 26. Okt., Seite 626-635 (DE-627)320456978 (DE-600)2006784-7 1525-1497 nnns volume:39 year:2023 number:4 day:26 month:10 pages:626-635 https://dx.doi.org/10.1007/s11606-023-08440-9 lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.61 VZ AR 39 2023 4 26 10 626-635 |
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Hynes, Denise M. @@aut@@ Niederhausen, Meike @@aut@@ Chen, Jason I. @@aut@@ Shahoumian, Troy A. @@aut@@ Rowneki, Mazhgan @@aut@@ Hickok, Alex @@aut@@ Shepherd-Banigan, Megan @@aut@@ Hawkins, Eric J. @@aut@@ Naylor, Jennifer @@aut@@ Teo, Alan @@aut@@ Govier, Diana J. @@aut@@ Berry, Kristin @@aut@@ McCready, Holly @@aut@@ Osborne, Thomas F. @@aut@@ Wong, Edwin @@aut@@ Hebert, Paul L. @@aut@@ Smith, Valerie A. @@aut@@ Bowling, C. Barrett @@aut@@ Boyko, Edward J. @@aut@@ Ioannou, George N. @@aut@@ Iwashyna, Theodore J. @@aut@@ Maciejewski, Matthew L. @@aut@@ O’Hare, Ann M. @@aut@@ Viglianti, Elizabeth M. @@aut@@ Bohnert, Amy S.-B. @@aut@@ |
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However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. 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Hynes, Denise M. |
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610 VZ 44.61 bkl Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans |
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Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans |
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Hynes, Denise M. Niederhausen, Meike Chen, Jason I. Shahoumian, Troy A. Rowneki, Mazhgan Hickok, Alex Shepherd-Banigan, Megan Hawkins, Eric J. Naylor, Jennifer Teo, Alan Govier, Diana J. Berry, Kristin McCready, Holly Osborne, Thomas F. Wong, Edwin Hebert, Paul L. Smith, Valerie A. Bowling, C. Barrett Boyko, Edward J. Ioannou, George N. Iwashyna, Theodore J. Maciejewski, Matthew L. O’Hare, Ann M. Viglianti, Elizabeth M. Bohnert, Amy S.-B. |
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risk of suicide-related outcomes after sars-cov-2 infection: results from a nationwide observational matched cohort of us veterans |
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Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans |
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Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 |
| abstractGer |
Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 |
| abstract_unstemmed |
Background Negative mental health-related effects of SARS-COV-2 infection are increasingly evident. However, the impact on suicide-related outcomes is poorly understood, especially among populations at elevated risk. Objective To determine risk of suicide attempts and other self-directed violence (SDV) after SARS-COV-2 infection in a high-risk population. Design We employed an observational design supported by comprehensive electronic health records from the Veterans Health Administration (VHA) to examine the association of SARS-COV-2 infection with suicide attempts and other SDV within one year of infection. Veterans with SARS-COV-2 infections were matched 1:5 with non-infected comparators each month. Three periods after index were evaluated: days 1–30, days 31–365, and days 1–365. Participants VHA patients infected with SARS-COV-2 between March 1, 2020 and March 31, 2021 and matched non-infected Veteran comparators. Main Measures Suicide attempt and other SDV events for the COVID-19 and non-infected comparator groups were analyzed using incidence rates per 100,000 person years and hazard ratios from Cox regressions modeling time from matched index date to first event. Subgroups were also examined. Key Results 198,938 veterans with SARS-COV-2 (COVID-19 group) and 992,036 comparators were included. Unadjusted one-year incidence per 100,000 for suicide attempt and other SDV was higher among the COVID-19 group: 355 vs 250 and 327 vs 235, respectively. The COVID-19 group had higher risk than comparators for suicide attempts: days 1–30 hazard ratio (HR) = 2.54 (CI:2.05, 3.15), days 31–365 HR = 1.30 (CI:1.19, 1.43) and days 1–365 HR = 1.41 (CI:1.30, 1.54), and for other SDV: days 1–30 HR = 1.94 (CI:1.51, 2.49), days 31–365 HR = 1.32 (CI:1.20, 1.45) and days 1–365 HR = 1.38 (CI:1.26, 1.51). Conclusions COVID-19 patients had higher risks of both suicide attempts and other forms of SDV compared to uninfected comparators, which persisted for at least one year after infection. Results support suicide risk screening of those infected with SARS-COV-2 to identify opportunities to prevent self-harm. © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023 |
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Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans |
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| score |
7.4000463 |