Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study

Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Talwar, Deepak [verfasserIn] Balamurugan, S [verfasserIn] Modi, Mahavir [verfasserIn] Salvi, Sundeep [verfasserIn] Lopez, Meena [verfasserIn] Shah, Rushika [verfasserIn] Vaidya, Abhijit [verfasserIn] Barne, Monica [verfasserIn] Madas, Sapna [verfasserIn] Kulkarni, Nandan [verfasserIn] Sawant, Sandesh [verfasserIn] Gogtay, Jaideep [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	Asthma Chronic obstructive pulmonary disease Forced expiratory volume Spirometer Forced vital capacity

Anmerkung:	© The Author(s) 2024

Übergeordnetes Werk:	Enthalten in: BMC pulmonary medicine - BioMed Central, 2001, 24(2024), 1 vom: 10. Mai
Übergeordnetes Werk:	volume:24 ; year:2024 ; number:1 ; day:10 ; month:05

Links:	Volltext

DOI / URN:	10.1186/s12890-024-02972-4

Katalog-ID:	SPR055812864

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245	1	0	\|a Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study
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520			\|a Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India)
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allfields	10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05
spelling	10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05
allfields_unstemmed	10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05
allfieldsGer	10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05
allfieldsSound	10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05
language	English
source	Enthalten in BMC pulmonary medicine 24(2024), 1 vom: 10. Mai volume:24 year:2024 number:1 day:10 month:05
sourceStr	Enthalten in BMC pulmonary medicine 24(2024), 1 vom: 10. Mai volume:24 year:2024 number:1 day:10 month:05
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Asthma Chronic obstructive pulmonary disease Forced expiratory volume Spirometer Forced vital capacity
dewey-raw	610
isfreeaccess_bool	true
container_title	BMC pulmonary medicine
authorswithroles_txt_mv	Talwar, Deepak @@aut@@ Balamurugan, S @@aut@@ Modi, Mahavir @@aut@@ Salvi, Sundeep @@aut@@ Lopez, Meena @@aut@@ Shah, Rushika @@aut@@ Vaidya, Abhijit @@aut@@ Barne, Monica @@aut@@ Madas, Sapna @@aut@@ Kulkarni, Nandan @@aut@@ Sawant, Sandesh @@aut@@ Gogtay, Jaideep @@aut@@
publishDateDaySort_date	2024-05-10T00:00:00Z
hierarchy_top_id	335489125
dewey-sort	3610
id	SPR055812864
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">SPR055812864</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240511064711.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240511s2024 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1186/s12890-024-02972-4</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR055812864</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s12890-024-02972-4-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Talwar, Deepak</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© The Author(s) 2024</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. 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author	Talwar, Deepak
spellingShingle	Talwar, Deepak ddc 610 bkl 44.00 misc Asthma misc Chronic obstructive pulmonary disease misc Forced expiratory volume misc Spirometer misc Forced vital capacity Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study
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topic_title	610 VZ 44.00 bkl Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213
topic	ddc 610 bkl 44.00 misc Asthma misc Chronic obstructive pulmonary disease misc Forced expiratory volume misc Spirometer misc Forced vital capacity
topic_unstemmed	ddc 610 bkl 44.00 misc Asthma misc Chronic obstructive pulmonary disease misc Forced expiratory volume misc Spirometer misc Forced vital capacity
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title	Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study
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title_full	Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study
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author_browse	Talwar, Deepak Balamurugan, S Modi, Mahavir Salvi, Sundeep Lopez, Meena Shah, Rushika Vaidya, Abhijit Barne, Monica Madas, Sapna Kulkarni, Nandan Sawant, Sandesh Gogtay, Jaideep
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title_sort	comparison of a portable, pneumotach flow-sensor–based spirometer (spirofy™) with the vitalograph alpha touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and copd patients—a randomized, crossover study
title_auth	Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study
abstract	Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) © The Author(s) 2024
abstractGer	Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) © The Author(s) 2024
abstract_unstemmed	Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) © The Author(s) 2024
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title_short	Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study
url	https://dx.doi.org/10.1186/s12890-024-02972-4
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author2	Balamurugan, S Modi, Mahavir Salvi, Sundeep Lopez, Meena Shah, Rushika Vaidya, Abhijit Barne, Monica Madas, Sapna Kulkarni, Nandan Sawant, Sandesh Gogtay, Jaideep
author2Str	Balamurugan, S Modi, Mahavir Salvi, Sundeep Lopez, Meena Shah, Rushika Vaidya, Abhijit Barne, Monica Madas, Sapna Kulkarni, Nandan Sawant, Sandesh Gogtay, Jaideep
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up_date	2024-07-03T18:11:37.539Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">SPR055812864</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240511064711.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240511s2024 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1186/s12890-024-02972-4</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR055812864</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s12890-024-02972-4-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Talwar, Deepak</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© The Author(s) 2024</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. 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Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study

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