Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study
Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in meas...
Ausführliche Beschreibung
Autor*in: |
Talwar, Deepak [verfasserIn] Balamurugan, S [verfasserIn] Modi, Mahavir [verfasserIn] Salvi, Sundeep [verfasserIn] Lopez, Meena [verfasserIn] Shah, Rushika [verfasserIn] Vaidya, Abhijit [verfasserIn] Barne, Monica [verfasserIn] Madas, Sapna [verfasserIn] Kulkarni, Nandan [verfasserIn] Sawant, Sandesh [verfasserIn] Gogtay, Jaideep [verfasserIn] |
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E-Artikel |
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Englisch |
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2024 |
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Anmerkung: |
© The Author(s) 2024 |
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Übergeordnetes Werk: |
Enthalten in: BMC pulmonary medicine - BioMed Central, 2001, 24(2024), 1 vom: 10. Mai |
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Übergeordnetes Werk: |
volume:24 ; year:2024 ; number:1 ; day:10 ; month:05 |
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DOI / URN: |
10.1186/s12890-024-02972-4 |
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SPR055812864 |
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245 | 1 | 0 | |a Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study |
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520 | |a Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) | ||
650 | 4 | |a Asthma |7 (dpeaa)DE-He213 | |
650 | 4 | |a Chronic obstructive pulmonary disease |7 (dpeaa)DE-He213 | |
650 | 4 | |a Forced expiratory volume |7 (dpeaa)DE-He213 | |
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700 | 1 | |a Balamurugan, S |e verfasserin |4 aut | |
700 | 1 | |a Modi, Mahavir |e verfasserin |4 aut | |
700 | 1 | |a Salvi, Sundeep |e verfasserin |4 aut | |
700 | 1 | |a Lopez, Meena |e verfasserin |4 aut | |
700 | 1 | |a Shah, Rushika |e verfasserin |4 aut | |
700 | 1 | |a Vaidya, Abhijit |e verfasserin |4 aut | |
700 | 1 | |a Barne, Monica |e verfasserin |4 aut | |
700 | 1 | |a Madas, Sapna |e verfasserin |4 aut | |
700 | 1 | |a Kulkarni, Nandan |e verfasserin |4 aut | |
700 | 1 | |a Sawant, Sandesh |e verfasserin |4 aut | |
700 | 1 | |a Gogtay, Jaideep |e verfasserin |4 aut | |
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10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05 |
spelling |
10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05 |
allfields_unstemmed |
10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05 |
allfieldsGer |
10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05 |
allfieldsSound |
10.1186/s12890-024-02972-4 doi (DE-627)SPR055812864 (SPR)s12890-024-02972-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Talwar, Deepak verfasserin aut Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 Balamurugan, S verfasserin aut Modi, Mahavir verfasserin aut Salvi, Sundeep verfasserin aut Lopez, Meena verfasserin aut Shah, Rushika verfasserin aut Vaidya, Abhijit verfasserin aut Barne, Monica verfasserin aut Madas, Sapna verfasserin aut Kulkarni, Nandan verfasserin aut Sawant, Sandesh verfasserin aut Gogtay, Jaideep verfasserin aut Enthalten in BMC pulmonary medicine BioMed Central, 2001 24(2024), 1 vom: 10. Mai (DE-627)335489125 (DE-600)2059871-3 1471-2466 nnns volume:24 year:2024 number:1 day:10 month:05 https://dx.doi.org/10.1186/s12890-024-02972-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 10 05 |
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Enthalten in BMC pulmonary medicine 24(2024), 1 vom: 10. Mai volume:24 year:2024 number:1 day:10 month:05 |
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Asthma Chronic obstructive pulmonary disease Forced expiratory volume Spirometer Forced vital capacity |
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Talwar, Deepak @@aut@@ Balamurugan, S @@aut@@ Modi, Mahavir @@aut@@ Salvi, Sundeep @@aut@@ Lopez, Meena @@aut@@ Shah, Rushika @@aut@@ Vaidya, Abhijit @@aut@@ Barne, Monica @@aut@@ Madas, Sapna @@aut@@ Kulkarni, Nandan @@aut@@ Sawant, Sandesh @@aut@@ Gogtay, Jaideep @@aut@@ |
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In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. 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Talwar, Deepak |
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Talwar, Deepak ddc 610 bkl 44.00 misc Asthma misc Chronic obstructive pulmonary disease misc Forced expiratory volume misc Spirometer misc Forced vital capacity Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study |
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610 VZ 44.00 bkl Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study Asthma (dpeaa)DE-He213 Chronic obstructive pulmonary disease (dpeaa)DE-He213 Forced expiratory volume (dpeaa)DE-He213 Spirometer (dpeaa)DE-He213 Forced vital capacity (dpeaa)DE-He213 |
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Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study |
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Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study |
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Talwar, Deepak Balamurugan, S Modi, Mahavir Salvi, Sundeep Lopez, Meena Shah, Rushika Vaidya, Abhijit Barne, Monica Madas, Sapna Kulkarni, Nandan Sawant, Sandesh Gogtay, Jaideep |
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comparison of a portable, pneumotach flow-sensor–based spirometer (spirofy™) with the vitalograph alpha touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and copd patients—a randomized, crossover study |
title_auth |
Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study |
abstract |
Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) © The Author(s) 2024 |
abstractGer |
Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) © The Author(s) 2024 |
abstract_unstemmed |
Background Spirofy™ is India’s first portable, pneumotach flow-sensor-based digital spirometer developed to diagnose asthma and chronic obstructive pulmonary disease (COPD). In this study, we compared the performance of the Spirofy™ device with that of the Vitalograph Alpha Touch™ spirometer in measuring the lung capacities of healthy individuals, asthmatics, and COPD patients. We also assessed the inter-device variability between two Spirofy™ devices. Methods In a randomized, three-way crossover, open-label study, we measured the differences in forced expiratory volume in the first second ($ FEV_{1} $) and forced vital capacity (FVC) between the Spirofy™ and Vitalograph Alpha Touch™ spirometers. A proportion of the $ FEV_{1} $/FVC ratio distribution of < 0.7 was used to compare the diagnostic accuracies of the Spirofy™ with Vitalograph™ Alpha Touch™ spirometers. Results Ninety subjects participated in this study. The mean ± SD FVC values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 2.60 ± 1.05 L, 2.64 ± 1.04 L, and 2.67 ± 1.04 L, respectively. The mean ± SD $ FEV_{1} $ values obtained from the Spirofy™ 1, Spirofy™ 2, and Vitalograph Alpha Touch™ devices were 1.87 ± 0.92 (L), 1.88 ± 0.92 (L), and 1.93 ± 0.93 (L), respectively. A significant positive correlation was found between the FVC and $ FEV_{1} $ values recorded by Vitalograph Alpha Touch™, Spirofy™ 1, and Spirofy™ 2. As compared to Vitalograph Alpha Touch™, the Spirofy™ device showed good sensitivity (97%), specificity (90%), and overall accuracy (93.3%) at an $ FEV_{1} $/FVC ratio < 0.7. No inter-device variability was observed between the two Spirofy™ devices. Conclusion Spirofy™ is a portable and easy-to-use device and is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the diagnosis of COPD and asthma. Trial registration CTRI/2021/09/036492 (Clinical Trials Registry - India) © The Author(s) 2024 |
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Comparison of a portable, pneumotach flow-sensor–based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients—a randomized, crossover study |
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Balamurugan, S Modi, Mahavir Salvi, Sundeep Lopez, Meena Shah, Rushika Vaidya, Abhijit Barne, Monica Madas, Sapna Kulkarni, Nandan Sawant, Sandesh Gogtay, Jaideep |
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Balamurugan, S Modi, Mahavir Salvi, Sundeep Lopez, Meena Shah, Rushika Vaidya, Abhijit Barne, Monica Madas, Sapna Kulkarni, Nandan Sawant, Sandesh Gogtay, Jaideep |
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score |
7.4003057 |