Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test

Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective...
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Autor*in:	Ma, Yun [verfasserIn] Chai, Wenying [verfasserIn] Bu, Deyong [verfasserIn] Feng, Xuemin [verfasserIn] Ashford, J. Wesson [verfasserIn] He, Limei [verfasserIn] Zheng, Ying [verfasserIn] Ashford, Curtis B. [verfasserIn] Li, Feng [verfasserIn] Li, Jun [verfasserIn] Dong, Yuan [verfasserIn] Li, Shumo [verfasserIn] Zhou, Xianbo [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	MemTrax memory test Breast cancer Chemobrain

Anmerkung:	© The Author(s) 2024

Übergeordnetes Werk:	Enthalten in: BMC women's health - BioMed Central, 2001, 24(2024), 1 vom: 17. Juli
Übergeordnetes Werk:	volume:24 ; year:2024 ; number:1 ; day:17 ; month:07

Links:	Volltext

DOI / URN:	10.1186/s12905-024-03251-4

Katalog-ID:	SPR056629419

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allfields	10.1186/s12905-024-03251-4 doi (DE-627)SPR056629419 (SPR)s12905-024-03251-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Ma, Yun verfasserin aut Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. The fact that the more objective MemTrax could not detect the impairment could alleviate patients’ concerns which in turn would be beneficial for patients’ mental health. MemTrax memory test (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Chemobrain (dpeaa)DE-He213 Chai, Wenying verfasserin aut Bu, Deyong verfasserin aut Feng, Xuemin verfasserin aut Ashford, J. Wesson verfasserin aut He, Limei verfasserin aut Zheng, Ying verfasserin aut Ashford, Curtis B. verfasserin aut Li, Feng verfasserin aut Li, Jun verfasserin aut Dong, Yuan verfasserin aut Li, Shumo verfasserin aut Zhou, Xianbo verfasserin aut Enthalten in BMC women's health BioMed Central, 2001 24(2024), 1 vom: 17. Juli (DE-627)331018853 (DE-600)2050444-5 1472-6874 nnns volume:24 year:2024 number:1 day:17 month:07 https://dx.doi.org/10.1186/s12905-024-03251-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 17 07
spelling	10.1186/s12905-024-03251-4 doi (DE-627)SPR056629419 (SPR)s12905-024-03251-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Ma, Yun verfasserin aut Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. The fact that the more objective MemTrax could not detect the impairment could alleviate patients’ concerns which in turn would be beneficial for patients’ mental health. MemTrax memory test (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Chemobrain (dpeaa)DE-He213 Chai, Wenying verfasserin aut Bu, Deyong verfasserin aut Feng, Xuemin verfasserin aut Ashford, J. Wesson verfasserin aut He, Limei verfasserin aut Zheng, Ying verfasserin aut Ashford, Curtis B. verfasserin aut Li, Feng verfasserin aut Li, Jun verfasserin aut Dong, Yuan verfasserin aut Li, Shumo verfasserin aut Zhou, Xianbo verfasserin aut Enthalten in BMC women's health BioMed Central, 2001 24(2024), 1 vom: 17. Juli (DE-627)331018853 (DE-600)2050444-5 1472-6874 nnns volume:24 year:2024 number:1 day:17 month:07 https://dx.doi.org/10.1186/s12905-024-03251-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 17 07
allfields_unstemmed	10.1186/s12905-024-03251-4 doi (DE-627)SPR056629419 (SPR)s12905-024-03251-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Ma, Yun verfasserin aut Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. The fact that the more objective MemTrax could not detect the impairment could alleviate patients’ concerns which in turn would be beneficial for patients’ mental health. MemTrax memory test (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Chemobrain (dpeaa)DE-He213 Chai, Wenying verfasserin aut Bu, Deyong verfasserin aut Feng, Xuemin verfasserin aut Ashford, J. Wesson verfasserin aut He, Limei verfasserin aut Zheng, Ying verfasserin aut Ashford, Curtis B. verfasserin aut Li, Feng verfasserin aut Li, Jun verfasserin aut Dong, Yuan verfasserin aut Li, Shumo verfasserin aut Zhou, Xianbo verfasserin aut Enthalten in BMC women's health BioMed Central, 2001 24(2024), 1 vom: 17. Juli (DE-627)331018853 (DE-600)2050444-5 1472-6874 nnns volume:24 year:2024 number:1 day:17 month:07 https://dx.doi.org/10.1186/s12905-024-03251-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 17 07
allfieldsGer	10.1186/s12905-024-03251-4 doi (DE-627)SPR056629419 (SPR)s12905-024-03251-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Ma, Yun verfasserin aut Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. The fact that the more objective MemTrax could not detect the impairment could alleviate patients’ concerns which in turn would be beneficial for patients’ mental health. MemTrax memory test (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Chemobrain (dpeaa)DE-He213 Chai, Wenying verfasserin aut Bu, Deyong verfasserin aut Feng, Xuemin verfasserin aut Ashford, J. Wesson verfasserin aut He, Limei verfasserin aut Zheng, Ying verfasserin aut Ashford, Curtis B. verfasserin aut Li, Feng verfasserin aut Li, Jun verfasserin aut Dong, Yuan verfasserin aut Li, Shumo verfasserin aut Zhou, Xianbo verfasserin aut Enthalten in BMC women's health BioMed Central, 2001 24(2024), 1 vom: 17. Juli (DE-627)331018853 (DE-600)2050444-5 1472-6874 nnns volume:24 year:2024 number:1 day:17 month:07 https://dx.doi.org/10.1186/s12905-024-03251-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 17 07
allfieldsSound	10.1186/s12905-024-03251-4 doi (DE-627)SPR056629419 (SPR)s12905-024-03251-4-e DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Ma, Yun verfasserin aut Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. The fact that the more objective MemTrax could not detect the impairment could alleviate patients’ concerns which in turn would be beneficial for patients’ mental health. MemTrax memory test (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Chemobrain (dpeaa)DE-He213 Chai, Wenying verfasserin aut Bu, Deyong verfasserin aut Feng, Xuemin verfasserin aut Ashford, J. Wesson verfasserin aut He, Limei verfasserin aut Zheng, Ying verfasserin aut Ashford, Curtis B. verfasserin aut Li, Feng verfasserin aut Li, Jun verfasserin aut Dong, Yuan verfasserin aut Li, Shumo verfasserin aut Zhou, Xianbo verfasserin aut Enthalten in BMC women's health BioMed Central, 2001 24(2024), 1 vom: 17. Juli (DE-627)331018853 (DE-600)2050444-5 1472-6874 nnns volume:24 year:2024 number:1 day:17 month:07 https://dx.doi.org/10.1186/s12905-024-03251-4 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.00 VZ AR 24 2024 1 17 07
language	English
source	Enthalten in BMC women's health 24(2024), 1 vom: 17. Juli volume:24 year:2024 number:1 day:17 month:07
sourceStr	Enthalten in BMC women's health 24(2024), 1 vom: 17. Juli volume:24 year:2024 number:1 day:17 month:07
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	MemTrax memory test Breast cancer Chemobrain
dewey-raw	610
isfreeaccess_bool	true
container_title	BMC women's health
authorswithroles_txt_mv	Ma, Yun @@aut@@ Chai, Wenying @@aut@@ Bu, Deyong @@aut@@ Feng, Xuemin @@aut@@ Ashford, J. Wesson @@aut@@ He, Limei @@aut@@ Zheng, Ying @@aut@@ Ashford, Curtis B. @@aut@@ Li, Feng @@aut@@ Li, Jun @@aut@@ Dong, Yuan @@aut@@ Li, Shumo @@aut@@ Zhou, Xianbo @@aut@@
publishDateDaySort_date	2024-07-17T00:00:00Z
hierarchy_top_id	331018853
dewey-sort	3610
id	SPR056629419
language_de	englisch
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Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. 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author	Ma, Yun
spellingShingle	Ma, Yun ddc 610 bkl 44.00 misc MemTrax memory test misc Breast cancer misc Chemobrain Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test
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topic_title	610 VZ 44.00 bkl Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test MemTrax memory test (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Chemobrain (dpeaa)DE-He213
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title	Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test
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title_full	Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test
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author_browse	Ma, Yun Chai, Wenying Bu, Deyong Feng, Xuemin Ashford, J. Wesson He, Limei Zheng, Ying Ashford, Curtis B. Li, Feng Li, Jun Dong, Yuan Li, Shumo Zhou, Xianbo
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title_sort	toward better understanding and management of chemobrain: the potential utilities of the memtrax memory test
title_auth	Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test
abstract	Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. The fact that the more objective MemTrax could not detect the impairment could alleviate patients’ concerns which in turn would be beneficial for patients’ mental health. © The Author(s) 2024
abstractGer	Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. The fact that the more objective MemTrax could not detect the impairment could alleviate patients’ concerns which in turn would be beneficial for patients’ mental health. © The Author(s) 2024
abstract_unstemmed	Objective To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain. Methods In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments. Patients with chemobrain were identified using published criteria based on FACT-Cog scores, and MemTrax scores from chemobrain patients were analyzed. Results Fifty-six patients participated in this study, of which 41 participants completed 4 or more cycles of chemotherapy and were included in the final analyses here. Using the reported high end of minimal clinical differences (10.6 points) of FACT-Cog before and after chemotherapy, 18 patients suffered from chemobrain in this study. In these 18 chemobrain patients, no cognitive impairments were detected by MemTrax, which paradoxically demonstrated an improvement in the normal cognitive range. Conclusion The cognitive impairment induced by chemotherapy in breast cancer patients is detectable by the FACT-Cog in a Chinese cohort but is not detected by the MemTrax memory test. The fact that the more objective MemTrax could not detect the impairment could alleviate patients’ concerns which in turn would be beneficial for patients’ mental health. © The Author(s) 2024
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title_short	Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test
url	https://dx.doi.org/10.1186/s12905-024-03251-4
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author2	Chai, Wenying Bu, Deyong Feng, Xuemin Ashford, J. Wesson He, Limei Zheng, Ying Ashford, Curtis B. Li, Feng Li, Jun Dong, Yuan Li, Shumo Zhou, Xianbo
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