A low power frequency-programmable stimulation circuit for small rodent pacemaker
Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Pan, Fanny [verfasserIn] Avignon-Meseldzija, Émilie [verfasserIn] Elhabab, AlBaraa [verfasserIn] Todesco, Alban [verfasserIn] Mercier, Olaf [verfasserIn] Mika, Delphine [verfasserIn] Boulate, David [verfasserIn] Perros, Frédéric [verfasserIn] Kolar, Anthony [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2024 |
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| Schlagwörter: |
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| Anmerkung: |
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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| Übergeordnetes Werk: |
Enthalten in: Analog integrated circuits and signal processing - Springer US, 1991, 120(2024), 1 vom: Juli, Seite 125-139 |
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| Übergeordnetes Werk: |
volume:120 ; year:2024 ; number:1 ; month:07 ; pages:125-139 |
| Links: |
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| DOI / URN: |
10.1007/s10470-024-02282-z |
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| Katalog-ID: |
SPR056651341 |
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| 520 | |a Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. | ||
| 650 | 4 | |a Pacemaker |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Pacing waveform |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Stimulation circuit |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Biomedical circuit |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Relaxation oscillator |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Ultra-low power |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Avignon-Meseldzija, Émilie |e verfasserin |4 aut | |
| 700 | 1 | |a Elhabab, AlBaraa |e verfasserin |4 aut | |
| 700 | 1 | |a Todesco, Alban |e verfasserin |4 aut | |
| 700 | 1 | |a Mercier, Olaf |e verfasserin |4 aut | |
| 700 | 1 | |a Mika, Delphine |e verfasserin |4 aut | |
| 700 | 1 | |a Boulate, David |e verfasserin |4 aut | |
| 700 | 1 | |a Perros, Frédéric |e verfasserin |4 aut | |
| 700 | 1 | |a Kolar, Anthony |e verfasserin |4 aut | |
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10.1007/s10470-024-02282-z doi (DE-627)SPR056651341 (SPR)s10470-024-02282-z-e DE-627 ger DE-627 rakwb eng 004 VZ 53.55 bkl 53.73 bkl Pan, Fanny verfasserin aut A low power frequency-programmable stimulation circuit for small rodent pacemaker 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. Pacemaker (dpeaa)DE-He213 Pacing waveform (dpeaa)DE-He213 Stimulation circuit (dpeaa)DE-He213 Biomedical circuit (dpeaa)DE-He213 Relaxation oscillator (dpeaa)DE-He213 Ultra-low power (dpeaa)DE-He213 Avignon-Meseldzija, Émilie verfasserin aut Elhabab, AlBaraa verfasserin aut Todesco, Alban verfasserin aut Mercier, Olaf verfasserin aut Mika, Delphine verfasserin aut Boulate, David verfasserin aut Perros, Frédéric verfasserin aut Kolar, Anthony verfasserin aut Enthalten in Analog integrated circuits and signal processing Springer US, 1991 120(2024), 1 vom: Juli, Seite 125-139 (DE-627)271348925 (DE-600)1479772-0 1573-1979 nnns volume:120 year:2024 number:1 month:07 pages:125-139 https://dx.doi.org/10.1007/s10470-024-02282-z X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 53.55 VZ 53.73 VZ AR 120 2024 1 07 125-139 |
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10.1007/s10470-024-02282-z doi (DE-627)SPR056651341 (SPR)s10470-024-02282-z-e DE-627 ger DE-627 rakwb eng 004 VZ 53.55 bkl 53.73 bkl Pan, Fanny verfasserin aut A low power frequency-programmable stimulation circuit for small rodent pacemaker 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. Pacemaker (dpeaa)DE-He213 Pacing waveform (dpeaa)DE-He213 Stimulation circuit (dpeaa)DE-He213 Biomedical circuit (dpeaa)DE-He213 Relaxation oscillator (dpeaa)DE-He213 Ultra-low power (dpeaa)DE-He213 Avignon-Meseldzija, Émilie verfasserin aut Elhabab, AlBaraa verfasserin aut Todesco, Alban verfasserin aut Mercier, Olaf verfasserin aut Mika, Delphine verfasserin aut Boulate, David verfasserin aut Perros, Frédéric verfasserin aut Kolar, Anthony verfasserin aut Enthalten in Analog integrated circuits and signal processing Springer US, 1991 120(2024), 1 vom: Juli, Seite 125-139 (DE-627)271348925 (DE-600)1479772-0 1573-1979 nnns volume:120 year:2024 number:1 month:07 pages:125-139 https://dx.doi.org/10.1007/s10470-024-02282-z X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 53.55 VZ 53.73 VZ AR 120 2024 1 07 125-139 |
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10.1007/s10470-024-02282-z doi (DE-627)SPR056651341 (SPR)s10470-024-02282-z-e DE-627 ger DE-627 rakwb eng 004 VZ 53.55 bkl 53.73 bkl Pan, Fanny verfasserin aut A low power frequency-programmable stimulation circuit for small rodent pacemaker 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. Pacemaker (dpeaa)DE-He213 Pacing waveform (dpeaa)DE-He213 Stimulation circuit (dpeaa)DE-He213 Biomedical circuit (dpeaa)DE-He213 Relaxation oscillator (dpeaa)DE-He213 Ultra-low power (dpeaa)DE-He213 Avignon-Meseldzija, Émilie verfasserin aut Elhabab, AlBaraa verfasserin aut Todesco, Alban verfasserin aut Mercier, Olaf verfasserin aut Mika, Delphine verfasserin aut Boulate, David verfasserin aut Perros, Frédéric verfasserin aut Kolar, Anthony verfasserin aut Enthalten in Analog integrated circuits and signal processing Springer US, 1991 120(2024), 1 vom: Juli, Seite 125-139 (DE-627)271348925 (DE-600)1479772-0 1573-1979 nnns volume:120 year:2024 number:1 month:07 pages:125-139 https://dx.doi.org/10.1007/s10470-024-02282-z X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 53.55 VZ 53.73 VZ AR 120 2024 1 07 125-139 |
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10.1007/s10470-024-02282-z doi (DE-627)SPR056651341 (SPR)s10470-024-02282-z-e DE-627 ger DE-627 rakwb eng 004 VZ 53.55 bkl 53.73 bkl Pan, Fanny verfasserin aut A low power frequency-programmable stimulation circuit for small rodent pacemaker 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. Pacemaker (dpeaa)DE-He213 Pacing waveform (dpeaa)DE-He213 Stimulation circuit (dpeaa)DE-He213 Biomedical circuit (dpeaa)DE-He213 Relaxation oscillator (dpeaa)DE-He213 Ultra-low power (dpeaa)DE-He213 Avignon-Meseldzija, Émilie verfasserin aut Elhabab, AlBaraa verfasserin aut Todesco, Alban verfasserin aut Mercier, Olaf verfasserin aut Mika, Delphine verfasserin aut Boulate, David verfasserin aut Perros, Frédéric verfasserin aut Kolar, Anthony verfasserin aut Enthalten in Analog integrated circuits and signal processing Springer US, 1991 120(2024), 1 vom: Juli, Seite 125-139 (DE-627)271348925 (DE-600)1479772-0 1573-1979 nnns volume:120 year:2024 number:1 month:07 pages:125-139 https://dx.doi.org/10.1007/s10470-024-02282-z X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 53.55 VZ 53.73 VZ AR 120 2024 1 07 125-139 |
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10.1007/s10470-024-02282-z doi (DE-627)SPR056651341 (SPR)s10470-024-02282-z-e DE-627 ger DE-627 rakwb eng 004 VZ 53.55 bkl 53.73 bkl Pan, Fanny verfasserin aut A low power frequency-programmable stimulation circuit for small rodent pacemaker 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. Pacemaker (dpeaa)DE-He213 Pacing waveform (dpeaa)DE-He213 Stimulation circuit (dpeaa)DE-He213 Biomedical circuit (dpeaa)DE-He213 Relaxation oscillator (dpeaa)DE-He213 Ultra-low power (dpeaa)DE-He213 Avignon-Meseldzija, Émilie verfasserin aut Elhabab, AlBaraa verfasserin aut Todesco, Alban verfasserin aut Mercier, Olaf verfasserin aut Mika, Delphine verfasserin aut Boulate, David verfasserin aut Perros, Frédéric verfasserin aut Kolar, Anthony verfasserin aut Enthalten in Analog integrated circuits and signal processing Springer US, 1991 120(2024), 1 vom: Juli, Seite 125-139 (DE-627)271348925 (DE-600)1479772-0 1573-1979 nnns volume:120 year:2024 number:1 month:07 pages:125-139 https://dx.doi.org/10.1007/s10470-024-02282-z X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 53.55 VZ 53.73 VZ AR 120 2024 1 07 125-139 |
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Enthalten in Analog integrated circuits and signal processing 120(2024), 1 vom: Juli, Seite 125-139 volume:120 year:2024 number:1 month:07 pages:125-139 |
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Enthalten in Analog integrated circuits and signal processing 120(2024), 1 vom: Juli, Seite 125-139 volume:120 year:2024 number:1 month:07 pages:125-139 |
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Pacemaker Pacing waveform Stimulation circuit Biomedical circuit Relaxation oscillator Ultra-low power |
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Pan, Fanny @@aut@@ Avignon-Meseldzija, Émilie @@aut@@ Elhabab, AlBaraa @@aut@@ Todesco, Alban @@aut@@ Mercier, Olaf @@aut@@ Mika, Delphine @@aut@@ Boulate, David @@aut@@ Perros, Frédéric @@aut@@ Kolar, Anthony @@aut@@ |
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Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). 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Pan, Fanny |
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Pan, Fanny ddc 004 bkl 53.55 bkl 53.73 misc Pacemaker misc Pacing waveform misc Stimulation circuit misc Biomedical circuit misc Relaxation oscillator misc Ultra-low power A low power frequency-programmable stimulation circuit for small rodent pacemaker |
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004 VZ 53.55 bkl 53.73 bkl A low power frequency-programmable stimulation circuit for small rodent pacemaker Pacemaker (dpeaa)DE-He213 Pacing waveform (dpeaa)DE-He213 Stimulation circuit (dpeaa)DE-He213 Biomedical circuit (dpeaa)DE-He213 Relaxation oscillator (dpeaa)DE-He213 Ultra-low power (dpeaa)DE-He213 |
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ddc 004 bkl 53.55 bkl 53.73 misc Pacemaker misc Pacing waveform misc Stimulation circuit misc Biomedical circuit misc Relaxation oscillator misc Ultra-low power |
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a low power frequency-programmable stimulation circuit for small rodent pacemaker |
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A low power frequency-programmable stimulation circuit for small rodent pacemaker |
| abstract |
Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
| abstractGer |
Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
| abstract_unstemmed |
Abstract This article presents the design of an integrated, frequency-programmable stimulation circuit dedicated to small rodents for the study of pulmonary arterial hypertension. A complete architecture of the stimulation circuit is proposed, based on in vivo tests that have led to the stimulation waveform specification. The circuit is designed using XFAB 0.18 µm technology. The adopted design methodology allows to reduce the power consumption of command blocks to the minimum. Post-layout simulation results shows that the pacing rate can be tuned from 450 to 600 beats per minute (bpm). The total power consumption of the stimulation circuit is 196.1 µW, with 186 µW directly consumed by the voltage multipliers, H-Bridge and pacemaker load, 10.1 µW by the kilohertz-range VCO driver, and only 8.4 nW by the ultra-low power command generator. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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A low power frequency-programmable stimulation circuit for small rodent pacemaker |
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https://dx.doi.org/10.1007/s10470-024-02282-z |
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| author2 |
Avignon-Meseldzija, Émilie Elhabab, AlBaraa Todesco, Alban Mercier, Olaf Mika, Delphine Boulate, David Perros, Frédéric Kolar, Anthony |
| author2Str |
Avignon-Meseldzija, Émilie Elhabab, AlBaraa Todesco, Alban Mercier, Olaf Mika, Delphine Boulate, David Perros, Frédéric Kolar, Anthony |
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271348925 |
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c |
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| doi_str |
10.1007/s10470-024-02282-z |
| up_date |
2024-07-20T04:49:45.784Z |
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| score |
7.403097 |