Toward long-term and high-precision multimodal intracranial biomarker monitoring
Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompat...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Liu, Junduo [verfasserIn] Yuan, Ming [verfasserIn] Li, Baijun [verfasserIn] Long, Yunxiang [verfasserIn] Zhao, Jia [verfasserIn] Lin, Ting [verfasserIn] Xu, Feng [verfasserIn] Wang, Jun [verfasserIn] Fang, Yunsheng [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2024 |
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| Schlagwörter: |
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| Anmerkung: |
© The Author(s) 2024 |
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| Übergeordnetes Werk: |
Enthalten in: Med-X - Springer Nature Singapore, 2023, 2(2024), 1 vom: 26. Sept. |
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| Übergeordnetes Werk: |
volume:2 ; year:2024 ; number:1 ; day:26 ; month:09 |
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| DOI / URN: |
10.1007/s44258-024-00031-5 |
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SPR057487286 |
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| 520 | |a Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. | ||
| 520 | |a Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. | ||
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| 700 | 1 | |a Xu, Feng |e verfasserin |4 aut | |
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10.1007/s44258-024-00031-5 doi (DE-627)SPR057487286 (SPR)s44258-024-00031-5-e DE-627 ger DE-627 rakwb eng Liu, Junduo verfasserin aut Toward long-term and high-precision multimodal intracranial biomarker monitoring 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. Intracranial monitoring (dpeaa)DE-He213 Wireless monitoring (dpeaa)DE-He213 Ultrasound sensing (dpeaa)DE-He213 Metagel sensor (dpeaa)DE-He213 Implantable devices (dpeaa)DE-He213 Yuan, Ming verfasserin aut Li, Baijun verfasserin aut Long, Yunxiang verfasserin aut Zhao, Jia verfasserin aut Lin, Ting verfasserin aut Xu, Feng verfasserin aut Wang, Jun verfasserin aut Fang, Yunsheng verfasserin (orcid)0000-0003-2213-0167 aut Enthalten in Med-X Springer Nature Singapore, 2023 2(2024), 1 vom: 26. Sept. (DE-627)1845291662 2731-8710 nnns volume:2 year:2024 number:1 day:26 month:09 https://dx.doi.org/10.1007/s44258-024-00031-5 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER AR 2 2024 1 26 09 |
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10.1007/s44258-024-00031-5 doi (DE-627)SPR057487286 (SPR)s44258-024-00031-5-e DE-627 ger DE-627 rakwb eng Liu, Junduo verfasserin aut Toward long-term and high-precision multimodal intracranial biomarker monitoring 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. Intracranial monitoring (dpeaa)DE-He213 Wireless monitoring (dpeaa)DE-He213 Ultrasound sensing (dpeaa)DE-He213 Metagel sensor (dpeaa)DE-He213 Implantable devices (dpeaa)DE-He213 Yuan, Ming verfasserin aut Li, Baijun verfasserin aut Long, Yunxiang verfasserin aut Zhao, Jia verfasserin aut Lin, Ting verfasserin aut Xu, Feng verfasserin aut Wang, Jun verfasserin aut Fang, Yunsheng verfasserin (orcid)0000-0003-2213-0167 aut Enthalten in Med-X Springer Nature Singapore, 2023 2(2024), 1 vom: 26. Sept. (DE-627)1845291662 2731-8710 nnns volume:2 year:2024 number:1 day:26 month:09 https://dx.doi.org/10.1007/s44258-024-00031-5 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER AR 2 2024 1 26 09 |
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10.1007/s44258-024-00031-5 doi (DE-627)SPR057487286 (SPR)s44258-024-00031-5-e DE-627 ger DE-627 rakwb eng Liu, Junduo verfasserin aut Toward long-term and high-precision multimodal intracranial biomarker monitoring 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. Intracranial monitoring (dpeaa)DE-He213 Wireless monitoring (dpeaa)DE-He213 Ultrasound sensing (dpeaa)DE-He213 Metagel sensor (dpeaa)DE-He213 Implantable devices (dpeaa)DE-He213 Yuan, Ming verfasserin aut Li, Baijun verfasserin aut Long, Yunxiang verfasserin aut Zhao, Jia verfasserin aut Lin, Ting verfasserin aut Xu, Feng verfasserin aut Wang, Jun verfasserin aut Fang, Yunsheng verfasserin (orcid)0000-0003-2213-0167 aut Enthalten in Med-X Springer Nature Singapore, 2023 2(2024), 1 vom: 26. Sept. (DE-627)1845291662 2731-8710 nnns volume:2 year:2024 number:1 day:26 month:09 https://dx.doi.org/10.1007/s44258-024-00031-5 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER AR 2 2024 1 26 09 |
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10.1007/s44258-024-00031-5 doi (DE-627)SPR057487286 (SPR)s44258-024-00031-5-e DE-627 ger DE-627 rakwb eng Liu, Junduo verfasserin aut Toward long-term and high-precision multimodal intracranial biomarker monitoring 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. Intracranial monitoring (dpeaa)DE-He213 Wireless monitoring (dpeaa)DE-He213 Ultrasound sensing (dpeaa)DE-He213 Metagel sensor (dpeaa)DE-He213 Implantable devices (dpeaa)DE-He213 Yuan, Ming verfasserin aut Li, Baijun verfasserin aut Long, Yunxiang verfasserin aut Zhao, Jia verfasserin aut Lin, Ting verfasserin aut Xu, Feng verfasserin aut Wang, Jun verfasserin aut Fang, Yunsheng verfasserin (orcid)0000-0003-2213-0167 aut Enthalten in Med-X Springer Nature Singapore, 2023 2(2024), 1 vom: 26. Sept. (DE-627)1845291662 2731-8710 nnns volume:2 year:2024 number:1 day:26 month:09 https://dx.doi.org/10.1007/s44258-024-00031-5 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER AR 2 2024 1 26 09 |
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10.1007/s44258-024-00031-5 doi (DE-627)SPR057487286 (SPR)s44258-024-00031-5-e DE-627 ger DE-627 rakwb eng Liu, Junduo verfasserin aut Toward long-term and high-precision multimodal intracranial biomarker monitoring 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2024 Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. Intracranial monitoring (dpeaa)DE-He213 Wireless monitoring (dpeaa)DE-He213 Ultrasound sensing (dpeaa)DE-He213 Metagel sensor (dpeaa)DE-He213 Implantable devices (dpeaa)DE-He213 Yuan, Ming verfasserin aut Li, Baijun verfasserin aut Long, Yunxiang verfasserin aut Zhao, Jia verfasserin aut Lin, Ting verfasserin aut Xu, Feng verfasserin aut Wang, Jun verfasserin aut Fang, Yunsheng verfasserin (orcid)0000-0003-2213-0167 aut Enthalten in Med-X Springer Nature Singapore, 2023 2(2024), 1 vom: 26. Sept. (DE-627)1845291662 2731-8710 nnns volume:2 year:2024 number:1 day:26 month:09 https://dx.doi.org/10.1007/s44258-024-00031-5 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER AR 2 2024 1 26 09 |
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Toward long-term and high-precision multimodal intracranial biomarker monitoring |
| abstract |
Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. © The Author(s) 2024 |
| abstractGer |
Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. © The Author(s) 2024 |
| abstract_unstemmed |
Abstract Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of poor measurement accuracy, inability to monitor long-term and inadequate biocompatibility. To address these, minimally invasive implantable ultrasound metagel sensors have been developed for monitoring intracranial pressure, temperature, pH, and blood flow velocity. The sensor can quickly respond to changes in ultrasound frequency for high-precision monitoring of key physiological signals compared to current clinical gold standards. Additionally, the hydrogel exhibits excellent biocompatibility and can degrade almost completely within 18 weeks, without causing hematological disorders or systemic inflammatory responses. Highlights • Significance, challenge, and existing technologies of intracranial biomarker monitoring. • Design and characterization of ultrasound-sensitive metagel sensors for multimodal intracranial biomarker monitoring. • Conclusions and perspectives on the future development of intracranial biomarker monitoring. © The Author(s) 2024 |
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| title_short |
Toward long-term and high-precision multimodal intracranial biomarker monitoring |
| url |
https://dx.doi.org/10.1007/s44258-024-00031-5 |
| remote_bool |
true |
| author2 |
Yuan, Ming Li, Baijun Long, Yunxiang Zhao, Jia Lin, Ting Xu, Feng Wang, Jun Fang, Yunsheng |
| author2Str |
Yuan, Ming Li, Baijun Long, Yunxiang Zhao, Jia Lin, Ting Xu, Feng Wang, Jun Fang, Yunsheng |
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1845291662 |
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| doi_str |
10.1007/s44258-024-00031-5 |
| up_date |
2024-09-27T04:50:05.118Z |
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