Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties
In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transf...
Ausführliche Beschreibung
Autor*in: |
Javid, Hossein [verfasserIn] Amiri, Hamed [verfasserIn] Hashemi, Seyedeh Fatemeh [verfasserIn] Reihani, Amirali [verfasserIn] Mehri, Ali [verfasserIn] Hashemy, Seyed Isaac [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2024 |
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Anmerkung: |
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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Übergeordnetes Werk: |
Enthalten in: Journal of sol gel science and technology - Springer US, 1993, 112(2024), 2 vom: 14. Sept., Seite 524-532 |
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Übergeordnetes Werk: |
volume:112 ; year:2024 ; number:2 ; day:14 ; month:09 ; pages:524-532 |
Links: |
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DOI / URN: |
10.1007/s10971-024-06531-5 |
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Katalog-ID: |
SPR058191992 |
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520 | |a In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract | ||
520 | |a Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. | ||
650 | 4 | |a Cytotoxicity |7 (dpeaa)DE-He213 | |
650 | 4 | |a Zinc oxide nanoparticles |7 (dpeaa)DE-He213 | |
650 | 4 | |a Antifungal activity |7 (dpeaa)DE-He213 | |
650 | 4 | |a Oxidative properties |7 (dpeaa)DE-He213 | |
700 | 1 | |a Amiri, Hamed |e verfasserin |4 aut | |
700 | 1 | |a Hashemi, Seyedeh Fatemeh |e verfasserin |4 aut | |
700 | 1 | |a Reihani, Amirali |e verfasserin |4 aut | |
700 | 1 | |a Mehri, Ali |e verfasserin |4 aut | |
700 | 1 | |a Hashemy, Seyed Isaac |e verfasserin |4 aut | |
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10.1007/s10971-024-06531-5 doi (DE-627)SPR058191992 (SPR)s10971-024-06531-5-e DE-627 ger DE-627 rakwb eng 600 670 VZ 35.18 bkl 51.60 bkl Javid, Hossein verfasserin aut Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. Cytotoxicity (dpeaa)DE-He213 Zinc oxide nanoparticles (dpeaa)DE-He213 Antifungal activity (dpeaa)DE-He213 Oxidative properties (dpeaa)DE-He213 Amiri, Hamed verfasserin aut Hashemi, Seyedeh Fatemeh verfasserin aut Reihani, Amirali verfasserin aut Mehri, Ali verfasserin aut Hashemy, Seyed Isaac verfasserin aut Enthalten in Journal of sol gel science and technology Springer US, 1993 112(2024), 2 vom: 14. Sept., Seite 524-532 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:112 year:2024 number:2 day:14 month:09 pages:524-532 https://dx.doi.org/10.1007/s10971-024-06531-5 X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_72 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2548 GBV_ILN_2574 GBV_ILN_4029 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4116 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4155 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4311 GBV_ILN_4313 GBV_ILN_4314 GBV_ILN_4315 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4598 GBV_ILN_4700 35.18 VZ 51.60 VZ AR 112 2024 2 14 09 524-532 |
spelling |
10.1007/s10971-024-06531-5 doi (DE-627)SPR058191992 (SPR)s10971-024-06531-5-e DE-627 ger DE-627 rakwb eng 600 670 VZ 35.18 bkl 51.60 bkl Javid, Hossein verfasserin aut Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. Cytotoxicity (dpeaa)DE-He213 Zinc oxide nanoparticles (dpeaa)DE-He213 Antifungal activity (dpeaa)DE-He213 Oxidative properties (dpeaa)DE-He213 Amiri, Hamed verfasserin aut Hashemi, Seyedeh Fatemeh verfasserin aut Reihani, Amirali verfasserin aut Mehri, Ali verfasserin aut Hashemy, Seyed Isaac verfasserin aut Enthalten in Journal of sol gel science and technology Springer US, 1993 112(2024), 2 vom: 14. Sept., Seite 524-532 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:112 year:2024 number:2 day:14 month:09 pages:524-532 https://dx.doi.org/10.1007/s10971-024-06531-5 X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_72 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2548 GBV_ILN_2574 GBV_ILN_4029 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4116 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4155 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4311 GBV_ILN_4313 GBV_ILN_4314 GBV_ILN_4315 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4598 GBV_ILN_4700 35.18 VZ 51.60 VZ AR 112 2024 2 14 09 524-532 |
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10.1007/s10971-024-06531-5 doi (DE-627)SPR058191992 (SPR)s10971-024-06531-5-e DE-627 ger DE-627 rakwb eng 600 670 VZ 35.18 bkl 51.60 bkl Javid, Hossein verfasserin aut Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. Cytotoxicity (dpeaa)DE-He213 Zinc oxide nanoparticles (dpeaa)DE-He213 Antifungal activity (dpeaa)DE-He213 Oxidative properties (dpeaa)DE-He213 Amiri, Hamed verfasserin aut Hashemi, Seyedeh Fatemeh verfasserin aut Reihani, Amirali verfasserin aut Mehri, Ali verfasserin aut Hashemy, Seyed Isaac verfasserin aut Enthalten in Journal of sol gel science and technology Springer US, 1993 112(2024), 2 vom: 14. Sept., Seite 524-532 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:112 year:2024 number:2 day:14 month:09 pages:524-532 https://dx.doi.org/10.1007/s10971-024-06531-5 X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_72 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2548 GBV_ILN_2574 GBV_ILN_4029 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4116 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4155 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4311 GBV_ILN_4313 GBV_ILN_4314 GBV_ILN_4315 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4598 GBV_ILN_4700 35.18 VZ 51.60 VZ AR 112 2024 2 14 09 524-532 |
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10.1007/s10971-024-06531-5 doi (DE-627)SPR058191992 (SPR)s10971-024-06531-5-e DE-627 ger DE-627 rakwb eng 600 670 VZ 35.18 bkl 51.60 bkl Javid, Hossein verfasserin aut Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. Cytotoxicity (dpeaa)DE-He213 Zinc oxide nanoparticles (dpeaa)DE-He213 Antifungal activity (dpeaa)DE-He213 Oxidative properties (dpeaa)DE-He213 Amiri, Hamed verfasserin aut Hashemi, Seyedeh Fatemeh verfasserin aut Reihani, Amirali verfasserin aut Mehri, Ali verfasserin aut Hashemy, Seyed Isaac verfasserin aut Enthalten in Journal of sol gel science and technology Springer US, 1993 112(2024), 2 vom: 14. Sept., Seite 524-532 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:112 year:2024 number:2 day:14 month:09 pages:524-532 https://dx.doi.org/10.1007/s10971-024-06531-5 X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_72 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2548 GBV_ILN_2574 GBV_ILN_4029 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4116 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4155 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4311 GBV_ILN_4313 GBV_ILN_4314 GBV_ILN_4315 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4598 GBV_ILN_4700 35.18 VZ 51.60 VZ AR 112 2024 2 14 09 524-532 |
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10.1007/s10971-024-06531-5 doi (DE-627)SPR058191992 (SPR)s10971-024-06531-5-e DE-627 ger DE-627 rakwb eng 600 670 VZ 35.18 bkl 51.60 bkl Javid, Hossein verfasserin aut Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. Cytotoxicity (dpeaa)DE-He213 Zinc oxide nanoparticles (dpeaa)DE-He213 Antifungal activity (dpeaa)DE-He213 Oxidative properties (dpeaa)DE-He213 Amiri, Hamed verfasserin aut Hashemi, Seyedeh Fatemeh verfasserin aut Reihani, Amirali verfasserin aut Mehri, Ali verfasserin aut Hashemy, Seyed Isaac verfasserin aut Enthalten in Journal of sol gel science and technology Springer US, 1993 112(2024), 2 vom: 14. Sept., Seite 524-532 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:112 year:2024 number:2 day:14 month:09 pages:524-532 https://dx.doi.org/10.1007/s10971-024-06531-5 X:SPRINGER Resolving-System lizenzpflichtig Volltext SYSFLAG_0 GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_72 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2548 GBV_ILN_2574 GBV_ILN_4029 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4116 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4155 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4311 GBV_ILN_4313 GBV_ILN_4314 GBV_ILN_4315 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4598 GBV_ILN_4700 35.18 VZ 51.60 VZ AR 112 2024 2 14 09 524-532 |
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Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. 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Javid, Hossein |
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Javid, Hossein ddc 600 bkl 35.18 bkl 51.60 misc Cytotoxicity misc Zinc oxide nanoparticles misc Antifungal activity misc Oxidative properties Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties |
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600 670 VZ 35.18 bkl 51.60 bkl Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties Cytotoxicity (dpeaa)DE-He213 Zinc oxide nanoparticles (dpeaa)DE-He213 Antifungal activity (dpeaa)DE-He213 Oxidative properties (dpeaa)DE-He213 |
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Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties |
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multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties |
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Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties |
abstract |
In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
abstractGer |
In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
abstract_unstemmed |
In this research endeavor, ZnO nanoparticles were synthesized employing a sol–gel process, using a zinc nitrate salt, followed by calcination at 600 °C, to yield a final product in the form of a white powder. Characterization of the synthesized ZnO nanoparticles was accomplished using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) pattern analysis, ultraviolet–visible (UV–Vis) spectrophotometry, and transmission electron microscopy (TEM). Furthermore, the in vitro cytotoxicity of the nanoparticles against the SW480 colorectal cancer cell line was investigated using the Resazurin cell viability assay. Oxidative activity assessment involved reactive oxygen species measurement, as well as superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC) tests. Additionally, the antifungal effects against Candida albicans and Aspergillus flavus were evaluated, and minimum inhibitory concentration values at 50% and 90% inhibition were determined. Graphical Abstract Highlights Nanotechnology is the scientific study and manipulation of materials at the molecular scale.Zinc oxide nanoparticles exhibit unique properties with significant potential in various medical and basic science applications.Zinc oxide nanoparticles exhibit cytotoxicity against SW480 colorectal cancer cell lines, indicating their potential as anticancer agents.Zinc oxide nanoparticles enhance the production of oxygen free radicals within cancer cells, further supporting their anticancer properties.Zinc oxide nanoparticles exhibit notable antifungal properties, effectively combating pathogenic fungi like C. albicans and A. flavus. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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Multifunctional zinc oxide nanoparticles: investigating antifungal, cytotoxic, and oxidative properties |
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|
score |
7.40199 |