Alterations in eicosanoid levels during U937 bcl-xL tumour growth suppression and recovery in NU/NU mice in vivo—Involvement of phospholipase A2

• We report for the first time that the HX Analog, PBT-4, blocks AA release in vivo. • PBT-4, blocks growth of leukaemic U937 derived tumours in vivo. • During tumour growth blockade, AA release and 12-HETE formation was inhibited – other eicosanoids were blocked as well. • 2–3 weeks after stopping...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Pace-Asciak, Cecil R. [verfasserIn]

Li, Xiang

Reynaud, Denis

Qiao, Na

Demin, Peter

Abdelhaleem, Mohamed

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2013

Schlagwörter:

Hepoxilins

Phospholipase

Tumours

LCMSMS

Eicosanoids

Antagonists

Umfang:

5

Übergeordnetes Werk:

Enthalten in: Radial growth response of trees to seasonal soil humidity in a subtropical forest - Gheyret, Gheyur ELSEVIER, 2021, an international journal, New York, NY

Übergeordnetes Werk:

volume:107 ; year:2013 ; pages:43-47 ; extent:5

Links:

Volltext

DOI / URN:

10.1016/j.prostaglandins.2013.03.004

Katalog-ID:

ELV017054753

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