Apoptosis signal-regulating kinase-1 aggravates ROS-mediated striatal degeneration in 3-nitropropionic acid-infused mice
• Systemic infusion of 3-NP increased ROS and led striatal cell loss. • ASK1 down-regulation decreased striatal cell death without scavenging ROS. • Adding ASK1protein to SOD tg aggravated striatal degeneration. • ASK1 activation induced by ROS is an important step of the 3-NP pathophysiology....
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Cho, Kyoung Joo [verfasserIn] |
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| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2013 |
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| Schlagwörter: |
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| Umfang: |
6 |
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| Übergeordnetes Werk: |
Enthalten in: Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag - Zhang, Zhikun ELSEVIER, 2019, BBRC, Orlando, Fla |
|---|---|
| Übergeordnetes Werk: |
volume:441 ; year:2013 ; number:2 ; day:15 ; month:11 ; pages:280-285 ; extent:6 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.bbrc.2013.08.103 |
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Apoptosis signal-regulating kinase-1 aggravates ROS-mediated striatal degeneration in 3-nitropropionic acid-infused mice |
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• Systemic infusion of 3-NP increased ROS and led striatal cell loss. • ASK1 down-regulation decreased striatal cell death without scavenging ROS. • Adding ASK1protein to SOD tg aggravated striatal degeneration. • ASK1 activation induced by ROS is an important step of the 3-NP pathophysiology. |
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• Systemic infusion of 3-NP increased ROS and led striatal cell loss. • ASK1 down-regulation decreased striatal cell death without scavenging ROS. • Adding ASK1protein to SOD tg aggravated striatal degeneration. • ASK1 activation induced by ROS is an important step of the 3-NP pathophysiology. |
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• Systemic infusion of 3-NP increased ROS and led striatal cell loss. • ASK1 down-regulation decreased striatal cell death without scavenging ROS. • Adding ASK1protein to SOD tg aggravated striatal degeneration. • ASK1 activation induced by ROS is an important step of the 3-NP pathophysiology. |
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Apoptosis signal-regulating kinase-1 aggravates ROS-mediated striatal degeneration in 3-nitropropionic acid-infused mice |
| url |
https://doi.org/10.1016/j.bbrc.2013.08.103 |
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| author2 |
Kim, Hyun Woo Cheon, So Yeong Lee, Jong Eun Kim, Gyung Whan |
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Kim, Hyun Woo Cheon, So Yeong Lee, Jong Eun Kim, Gyung Whan |
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| doi_str |
10.1016/j.bbrc.2013.08.103 |
| up_date |
2024-07-06T21:06:25.463Z |
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