Development of an in vitro model of human bronchial epithelial barrier to study nanoparticle translocation
• Calu-3 cells was the most relevant respiratory model for studying NP translocation. • A549 and NCI-H292 cells grown on Transwell filters did not form a tight epithelium. • NP translocated respectively at 3%, 9% and 35% across Calu-3, NCI-H292 and A549 cells. • The TEER was not modified regardless...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
George, Isabelle [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
|---|
| Umfang: |
8 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Prenatal diagnostic testing decisions in twin pregnancies in the era of cell-free DNA screening - Janssen, Matthew ELSEVIER, 2022, official journal of the European Society of Toxicology in Vitro, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:29 ; year:2015 ; number:1 ; pages:51-58 ; extent:8 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.tiv.2014.08.003 |
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• Calu-3 cells was the most relevant respiratory model for studying NP translocation. • A549 and NCI-H292 cells grown on Transwell filters did not form a tight epithelium. • NP translocated respectively at 3%, 9% and 35% across Calu-3, NCI-H292 and A549 cells. • The TEER was not modified regardless the cell line used after 24h of treatment. |
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• Calu-3 cells was the most relevant respiratory model for studying NP translocation. • A549 and NCI-H292 cells grown on Transwell filters did not form a tight epithelium. • NP translocated respectively at 3%, 9% and 35% across Calu-3, NCI-H292 and A549 cells. • The TEER was not modified regardless the cell line used after 24h of treatment. |
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• Calu-3 cells was the most relevant respiratory model for studying NP translocation. • A549 and NCI-H292 cells grown on Transwell filters did not form a tight epithelium. • NP translocated respectively at 3%, 9% and 35% across Calu-3, NCI-H292 and A549 cells. • The TEER was not modified regardless the cell line used after 24h of treatment. |
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