Genome rearrangement of influenza virus for anti-viral drug screening
• The viral genome of A/California/04/2009 (H1N1) can be rearranged to express GFP or Gaussia luciferase (GLuc). • Amantadine sensitive and resistant GLuc expressing variants were evaluated for anti-viral screening in the presence of amantadine. • Viral expressed luciferase was shown to be suitable...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Sutton, Troy C. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Schlagwörter: |
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| Umfang: |
10 |
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| Übergeordnetes Werk: |
Enthalten in: AKT-mediated enhanced aerobic glycolysis causes acquired radioresistance by human tumor cells - Shimura, Tsutomu ELSEVIER, 2014, an international journal of molecular and cellular virology, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:189 ; year:2014 ; day:30 ; month:08 ; pages:14-23 ; extent:10 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.virusres.2014.05.003 |
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| 520 | |a • The viral genome of A/California/04/2009 (H1N1) can be rearranged to express GFP or Gaussia luciferase (GLuc). • Amantadine sensitive and resistant GLuc expressing variants were evaluated for anti-viral screening in the presence of amantadine. • Viral expressed luciferase was shown to be suitable for in vitro and in vivo anti-viral screening. | ||
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• The viral genome of A/California/04/2009 (H1N1) can be rearranged to express GFP or Gaussia luciferase (GLuc). • Amantadine sensitive and resistant GLuc expressing variants were evaluated for anti-viral screening in the presence of amantadine. • Viral expressed luciferase was shown to be suitable for in vitro and in vivo anti-viral screening. |
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• The viral genome of A/California/04/2009 (H1N1) can be rearranged to express GFP or Gaussia luciferase (GLuc). • Amantadine sensitive and resistant GLuc expressing variants were evaluated for anti-viral screening in the presence of amantadine. • Viral expressed luciferase was shown to be suitable for in vitro and in vivo anti-viral screening. |
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• The viral genome of A/California/04/2009 (H1N1) can be rearranged to express GFP or Gaussia luciferase (GLuc). • Amantadine sensitive and resistant GLuc expressing variants were evaluated for anti-viral screening in the presence of amantadine. • Viral expressed luciferase was shown to be suitable for in vitro and in vivo anti-viral screening. |
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