SILA-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant Mycobacterium tuberculosis, and in vivo in a murine tuberculosis model
• SILA-421 has bactericidal activity towards Mycobacterium tuberculosis strains of the Beijing genotype. • SILA-421 enhanced the mycobacterial killing capacity of isoniazid and rifampicin. • SILA-421 prevented the emergence of isoniazid resistance.
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de Knegt, Gerjo J. [verfasserIn] |
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2015 |
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Enthalten in: Advanced constraint propagation for the combined car sequencing and level scheduling problem - Yavuz, Mesut ELSEVIER, 2018, Amsterdam [u.a.] |
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volume:46 ; year:2015 ; number:1 ; pages:66-72 ; extent:7 |
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10.1016/j.ijantimicag.2015.02.025 |
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author-letter |
de Knegt, Gerjo J. |
doi_str_mv |
10.1016/j.ijantimicag.2015.02.025 |
dewey-full |
610 650 |
title_sort |
sila-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant mycobacterium tuberculosis, and in vivo in a murine tuberculosis model |
title_auth |
SILA-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant Mycobacterium tuberculosis, and in vivo in a murine tuberculosis model |
abstract |
• SILA-421 has bactericidal activity towards Mycobacterium tuberculosis strains of the Beijing genotype. • SILA-421 enhanced the mycobacterial killing capacity of isoniazid and rifampicin. • SILA-421 prevented the emergence of isoniazid resistance. |
abstractGer |
• SILA-421 has bactericidal activity towards Mycobacterium tuberculosis strains of the Beijing genotype. • SILA-421 enhanced the mycobacterial killing capacity of isoniazid and rifampicin. • SILA-421 prevented the emergence of isoniazid resistance. |
abstract_unstemmed |
• SILA-421 has bactericidal activity towards Mycobacterium tuberculosis strains of the Beijing genotype. • SILA-421 enhanced the mycobacterial killing capacity of isoniazid and rifampicin. • SILA-421 prevented the emergence of isoniazid resistance. |
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container_issue |
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title_short |
SILA-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant Mycobacterium tuberculosis, and in vivo in a murine tuberculosis model |
url |
https://doi.org/10.1016/j.ijantimicag.2015.02.025 |
remote_bool |
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author2 |
Bakker-Woudenberg, Irma A.J.M. van Soolingen, Dick Aarnoutse, Rob Boeree, Martin J. de Steenwinkel, Jurriaan E.M. |
author2Str |
Bakker-Woudenberg, Irma A.J.M. van Soolingen, Dick Aarnoutse, Rob Boeree, Martin J. de Steenwinkel, Jurriaan E.M. |
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doi_str |
10.1016/j.ijantimicag.2015.02.025 |
up_date |
2024-07-06T21:36:04.703Z |
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