SILA-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant Mycobacterium tuberculosis, and in vivo in a murine tuberculosis model
• SILA-421 has bactericidal activity towards Mycobacterium tuberculosis strains of the Beijing genotype. • SILA-421 enhanced the mycobacterial killing capacity of isoniazid and rifampicin. • SILA-421 prevented the emergence of isoniazid resistance.
Gespeichert in:
| Autor*in: |
de Knegt, Gerjo J. [verfasserIn] |
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E-Artikel |
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Englisch |
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2015 |
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7 |
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Enthalten in: Advanced constraint propagation for the combined car sequencing and level scheduling problem - Yavuz, Mesut ELSEVIER, 2018, Amsterdam [u.a.] |
|---|---|
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volume:46 ; year:2015 ; number:1 ; pages:66-72 ; extent:7 |
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10.1016/j.ijantimicag.2015.02.025 |
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Advanced constraint propagation for the combined car sequencing and level scheduling problem |
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de Knegt, Gerjo J. |
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de Knegt, Gerjo J. |
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sila-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant mycobacterium tuberculosis, and in vivo in a murine tuberculosis model |
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SILA-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant Mycobacterium tuberculosis, and in vivo in a murine tuberculosis model |
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• SILA-421 has bactericidal activity towards Mycobacterium tuberculosis strains of the Beijing genotype. • SILA-421 enhanced the mycobacterial killing capacity of isoniazid and rifampicin. • SILA-421 prevented the emergence of isoniazid resistance. |
| abstractGer |
• SILA-421 has bactericidal activity towards Mycobacterium tuberculosis strains of the Beijing genotype. • SILA-421 enhanced the mycobacterial killing capacity of isoniazid and rifampicin. • SILA-421 prevented the emergence of isoniazid resistance. |
| abstract_unstemmed |
• SILA-421 has bactericidal activity towards Mycobacterium tuberculosis strains of the Beijing genotype. • SILA-421 enhanced the mycobacterial killing capacity of isoniazid and rifampicin. • SILA-421 prevented the emergence of isoniazid resistance. |
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SILA-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant Mycobacterium tuberculosis, and in vivo in a murine tuberculosis model |
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https://doi.org/10.1016/j.ijantimicag.2015.02.025 |
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Bakker-Woudenberg, Irma A.J.M. van Soolingen, Dick Aarnoutse, Rob Boeree, Martin J. de Steenwinkel, Jurriaan E.M. |
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Bakker-Woudenberg, Irma A.J.M. van Soolingen, Dick Aarnoutse, Rob Boeree, Martin J. de Steenwinkel, Jurriaan E.M. |
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