Does the crystal habit modulate the genotoxic potential of silica particles? A cytogenetic evaluation in human and murine cell lines
• Crystalline and amorphous silica sharing the same surface features were used. • Genotoxic potential of pure quartz and vitreous silica was tested in vitro. • Human pulmonary epithelial and murine macrophages cell lines were selected. • Comet assay, micronucleus test, trypan blue method were select...
Ausführliche Beschreibung
Autor*in: |
Guidi, P. [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2015 |
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Schlagwörter: |
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Umfang: |
7 |
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Übergeordnetes Werk: |
Enthalten in: The phospholipase A - Murakami, Makoto ELSEVIER, 2023, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:792 ; year:2015 ; pages:46-52 ; extent:7 |
Links: |
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DOI / URN: |
10.1016/j.mrgentox.2015.07.005 |
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ELV039581608 |
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• Crystalline and amorphous silica sharing the same surface features were used. • Genotoxic potential of pure quartz and vitreous silica was tested in vitro. • Human pulmonary epithelial and murine macrophages cell lines were selected. • Comet assay, micronucleus test, trypan blue method were selected. • Quartz induced increased DNA damage in murine macrophages but not in human cells. |
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• Crystalline and amorphous silica sharing the same surface features were used. • Genotoxic potential of pure quartz and vitreous silica was tested in vitro. • Human pulmonary epithelial and murine macrophages cell lines were selected. • Comet assay, micronucleus test, trypan blue method were selected. • Quartz induced increased DNA damage in murine macrophages but not in human cells. |
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• Crystalline and amorphous silica sharing the same surface features were used. • Genotoxic potential of pure quartz and vitreous silica was tested in vitro. • Human pulmonary epithelial and murine macrophages cell lines were selected. • Comet assay, micronucleus test, trypan blue method were selected. • Quartz induced increased DNA damage in murine macrophages but not in human cells. |
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