Molecular bases of antifungal resistance in filamentous fungi
• Invasive mould infections are associated with substantial healthcare use and mortality rates in immunocompromised patients. • The burden of antifungal resistance in high-risk patients is becoming a major concern. • Azole resistance in Aspergillus spp. is attributed to cyp51A and non-cyp51A mutatio...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Sharma, Cheshta [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2017 |
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| Umfang: |
10 |
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| Übergeordnetes Werk: |
Enthalten in: Advanced constraint propagation for the combined car sequencing and level scheduling problem - Yavuz, Mesut ELSEVIER, 2018, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:50 ; year:2017 ; number:5 ; pages:607-616 ; extent:10 |
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| DOI / URN: |
10.1016/j.ijantimicag.2017.06.018 |
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| 520 | |a • Invasive mould infections are associated with substantial healthcare use and mortality rates in immunocompromised patients. • The burden of antifungal resistance in high-risk patients is becoming a major concern. • Azole resistance in Aspergillus spp. is attributed to cyp51A and non-cyp51A mutations. • Polyene and echinocandin resistance mechanisms are less understood in Aspergillus spp. • Non-rational use of fungicides increases the risk of antifungal resistance in agriculture and medicine. | ||
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• Invasive mould infections are associated with substantial healthcare use and mortality rates in immunocompromised patients. • The burden of antifungal resistance in high-risk patients is becoming a major concern. • Azole resistance in Aspergillus spp. is attributed to cyp51A and non-cyp51A mutations. • Polyene and echinocandin resistance mechanisms are less understood in Aspergillus spp. • Non-rational use of fungicides increases the risk of antifungal resistance in agriculture and medicine. |
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• Invasive mould infections are associated with substantial healthcare use and mortality rates in immunocompromised patients. • The burden of antifungal resistance in high-risk patients is becoming a major concern. • Azole resistance in Aspergillus spp. is attributed to cyp51A and non-cyp51A mutations. • Polyene and echinocandin resistance mechanisms are less understood in Aspergillus spp. • Non-rational use of fungicides increases the risk of antifungal resistance in agriculture and medicine. |
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• Invasive mould infections are associated with substantial healthcare use and mortality rates in immunocompromised patients. • The burden of antifungal resistance in high-risk patients is becoming a major concern. • Azole resistance in Aspergillus spp. is attributed to cyp51A and non-cyp51A mutations. • Polyene and echinocandin resistance mechanisms are less understood in Aspergillus spp. • Non-rational use of fungicides increases the risk of antifungal resistance in agriculture and medicine. |
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