The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia
• Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing,...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Mecocci, Patrizia [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2021 |
|---|
| Schlagwörter: |
|---|
| Übergeordnetes Werk: |
Enthalten in: Hierarchical nanoassembly of Ni/MoS - Fu, Zhuai ELSEVIER, 2022, ARR, Oxford [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:65 ; year:2021 ; pages:0 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.arr.2020.101210 |
|---|
| Katalog-ID: |
ELV052529436 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV052529436 | ||
| 003 | DE-627 | ||
| 005 | 20230624184444.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 210910s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.arr.2020.101210 |2 doi | |
| 028 | 5 | 2 | |a /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001242.pica |
| 035 | |a (DE-627)ELV052529436 | ||
| 035 | |a (ELSEVIER)S1568-1637(20)30345-7 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 540 |q VZ |
| 084 | |a 35.00 |2 bkl | ||
| 100 | 1 | |a Mecocci, Patrizia |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia |
| 264 | 1 | |c 2021 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a • Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. | ||
| 650 | 7 | |a Mitochondria |2 Elsevier | |
| 650 | 7 | |a Alzheimer’s disease |2 Elsevier | |
| 650 | 7 | |a Energy |2 Elsevier | |
| 650 | 7 | |a Aging |2 Elsevier | |
| 650 | 7 | |a Amyloid |2 Elsevier | |
| 650 | 7 | |a Entropy |2 Elsevier | |
| 650 | 7 | |a Dementia |2 Elsevier | |
| 700 | 1 | |a Boccardi, Virginia |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier |a Fu, Zhuai ELSEVIER |t Hierarchical nanoassembly of Ni/MoS |d 2022 |d ARR |g Oxford [u.a.] |w (DE-627)ELV007865341 |
| 773 | 1 | 8 | |g volume:65 |g year:2021 |g pages:0 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.arr.2020.101210 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a SSG-OLC-PHA | ||
| 936 | b | k | |a 35.00 |j Chemie: Allgemeines |q VZ |
| 951 | |a AR | ||
| 952 | |d 65 |j 2021 |h 0 | ||
| author_variant |
p m pm |
|---|---|
| matchkey_str |
mecoccipatriziaboccardivirginia:2021----:hipcoaigneetatsieoeouatninnhmi |
| hierarchy_sort_str |
2021 |
| bklnumber |
35.00 |
| publishDate |
2021 |
| allfields |
10.1016/j.arr.2020.101210 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001242.pica (DE-627)ELV052529436 (ELSEVIER)S1568-1637(20)30345-7 DE-627 ger DE-627 rakwb eng 540 VZ 35.00 bkl Mecocci, Patrizia verfasserin aut The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia Elsevier Boccardi, Virginia oth Enthalten in Elsevier Fu, Zhuai ELSEVIER Hierarchical nanoassembly of Ni/MoS 2022 ARR Oxford [u.a.] (DE-627)ELV007865341 volume:65 year:2021 pages:0 https://doi.org/10.1016/j.arr.2020.101210 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ AR 65 2021 0 |
| spelling |
10.1016/j.arr.2020.101210 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001242.pica (DE-627)ELV052529436 (ELSEVIER)S1568-1637(20)30345-7 DE-627 ger DE-627 rakwb eng 540 VZ 35.00 bkl Mecocci, Patrizia verfasserin aut The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia Elsevier Boccardi, Virginia oth Enthalten in Elsevier Fu, Zhuai ELSEVIER Hierarchical nanoassembly of Ni/MoS 2022 ARR Oxford [u.a.] (DE-627)ELV007865341 volume:65 year:2021 pages:0 https://doi.org/10.1016/j.arr.2020.101210 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ AR 65 2021 0 |
| allfields_unstemmed |
10.1016/j.arr.2020.101210 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001242.pica (DE-627)ELV052529436 (ELSEVIER)S1568-1637(20)30345-7 DE-627 ger DE-627 rakwb eng 540 VZ 35.00 bkl Mecocci, Patrizia verfasserin aut The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia Elsevier Boccardi, Virginia oth Enthalten in Elsevier Fu, Zhuai ELSEVIER Hierarchical nanoassembly of Ni/MoS 2022 ARR Oxford [u.a.] (DE-627)ELV007865341 volume:65 year:2021 pages:0 https://doi.org/10.1016/j.arr.2020.101210 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ AR 65 2021 0 |
| allfieldsGer |
10.1016/j.arr.2020.101210 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001242.pica (DE-627)ELV052529436 (ELSEVIER)S1568-1637(20)30345-7 DE-627 ger DE-627 rakwb eng 540 VZ 35.00 bkl Mecocci, Patrizia verfasserin aut The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia Elsevier Boccardi, Virginia oth Enthalten in Elsevier Fu, Zhuai ELSEVIER Hierarchical nanoassembly of Ni/MoS 2022 ARR Oxford [u.a.] (DE-627)ELV007865341 volume:65 year:2021 pages:0 https://doi.org/10.1016/j.arr.2020.101210 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ AR 65 2021 0 |
| allfieldsSound |
10.1016/j.arr.2020.101210 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001242.pica (DE-627)ELV052529436 (ELSEVIER)S1568-1637(20)30345-7 DE-627 ger DE-627 rakwb eng 540 VZ 35.00 bkl Mecocci, Patrizia verfasserin aut The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia Elsevier Boccardi, Virginia oth Enthalten in Elsevier Fu, Zhuai ELSEVIER Hierarchical nanoassembly of Ni/MoS 2022 ARR Oxford [u.a.] (DE-627)ELV007865341 volume:65 year:2021 pages:0 https://doi.org/10.1016/j.arr.2020.101210 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ AR 65 2021 0 |
| language |
English |
| source |
Enthalten in Hierarchical nanoassembly of Ni/MoS Oxford [u.a.] volume:65 year:2021 pages:0 |
| sourceStr |
Enthalten in Hierarchical nanoassembly of Ni/MoS Oxford [u.a.] volume:65 year:2021 pages:0 |
| format_phy_str_mv |
Article |
| bklname |
Chemie: Allgemeines |
| institution |
findex.gbv.de |
| topic_facet |
Mitochondria Alzheimer’s disease Energy Aging Amyloid Entropy Dementia |
| dewey-raw |
540 |
| isfreeaccess_bool |
false |
| container_title |
Hierarchical nanoassembly of Ni/MoS |
| authorswithroles_txt_mv |
Mecocci, Patrizia @@aut@@ Boccardi, Virginia @@oth@@ |
| publishDateDaySort_date |
2021-01-01T00:00:00Z |
| hierarchy_top_id |
ELV007865341 |
| dewey-sort |
3540 |
| id |
ELV052529436 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV052529436</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624184444.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">210910s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.arr.2020.101210</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">/cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001242.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV052529436</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1568-1637(20)30345-7</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">540</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">35.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Mecocci, Patrizia</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">• Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Mitochondria</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Alzheimer’s disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Energy</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Aging</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Amyloid</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Entropy</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Dementia</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Boccardi, Virginia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Fu, Zhuai ELSEVIER</subfield><subfield code="t">Hierarchical nanoassembly of Ni/MoS</subfield><subfield code="d">2022</subfield><subfield code="d">ARR</subfield><subfield code="g">Oxford [u.a.]</subfield><subfield code="w">(DE-627)ELV007865341</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:65</subfield><subfield code="g">year:2021</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.arr.2020.101210</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">35.00</subfield><subfield code="j">Chemie: Allgemeines</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">65</subfield><subfield code="j">2021</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| author |
Mecocci, Patrizia |
| spellingShingle |
Mecocci, Patrizia ddc 540 bkl 35.00 Elsevier Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia |
| authorStr |
Mecocci, Patrizia |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV007865341 |
| format |
electronic Article |
| dewey-ones |
540 - Chemistry & allied sciences |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
540 VZ 35.00 bkl The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia Elsevier |
| topic |
ddc 540 bkl 35.00 Elsevier Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia |
| topic_unstemmed |
ddc 540 bkl 35.00 Elsevier Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia |
| topic_browse |
ddc 540 bkl 35.00 Elsevier Mitochondria Elsevier Alzheimer’s disease Elsevier Energy Elsevier Aging Elsevier Amyloid Elsevier Entropy Elsevier Dementia |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
v b vb |
| hierarchy_parent_title |
Hierarchical nanoassembly of Ni/MoS |
| hierarchy_parent_id |
ELV007865341 |
| dewey-tens |
540 - Chemistry |
| hierarchy_top_title |
Hierarchical nanoassembly of Ni/MoS |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV007865341 |
| title |
The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia |
| ctrlnum |
(DE-627)ELV052529436 (ELSEVIER)S1568-1637(20)30345-7 |
| title_full |
The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia |
| author_sort |
Mecocci, Patrizia |
| journal |
Hierarchical nanoassembly of Ni/MoS |
| journalStr |
Hierarchical nanoassembly of Ni/MoS |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science |
| recordtype |
marc |
| publishDateSort |
2021 |
| contenttype_str_mv |
zzz |
| container_start_page |
0 |
| author_browse |
Mecocci, Patrizia |
| container_volume |
65 |
| class |
540 VZ 35.00 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Mecocci, Patrizia |
| doi_str_mv |
10.1016/j.arr.2020.101210 |
| dewey-full |
540 |
| title_sort |
impact of aging in dementia: it is time to refocus attention on the main risk factor of dementia |
| title_auth |
The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia |
| abstract |
• Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. |
| abstractGer |
• Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. |
| abstract_unstemmed |
• Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
| title_short |
The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia |
| url |
https://doi.org/10.1016/j.arr.2020.101210 |
| remote_bool |
true |
| author2 |
Boccardi, Virginia |
| author2Str |
Boccardi, Virginia |
| ppnlink |
ELV007865341 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth |
| doi_str |
10.1016/j.arr.2020.101210 |
| up_date |
2024-07-06T23:16:50.701Z |
| _version_ |
1803873482914660352 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV052529436</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230624184444.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">210910s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.arr.2020.101210</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">/cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001242.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV052529436</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1568-1637(20)30345-7</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">540</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">35.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Mecocci, Patrizia</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The impact of aging in dementia: It is time to refocus attention on the main risk factor of dementia</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">• Alzheimer’s disease (AD) represents the most common form of dementia in old age subjects.. • Disease-modifier therapies and based on the amyloid hypothesis have failed in RCTs and no cure is available up to now. • In old age neurodegeneration is related to a progressive energetic failure causing, among other damages, amyloid accumulation. • The optimization of brain energetics should become a key component in future strategies for preventing and treating dementia.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Mitochondria</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Alzheimer’s disease</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Energy</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Aging</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Amyloid</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Entropy</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Dementia</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Boccardi, Virginia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Fu, Zhuai ELSEVIER</subfield><subfield code="t">Hierarchical nanoassembly of Ni/MoS</subfield><subfield code="d">2022</subfield><subfield code="d">ARR</subfield><subfield code="g">Oxford [u.a.]</subfield><subfield code="w">(DE-627)ELV007865341</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:65</subfield><subfield code="g">year:2021</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.arr.2020.101210</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">35.00</subfield><subfield code="j">Chemie: Allgemeines</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">65</subfield><subfield code="j">2021</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| score |
7.39927 |