NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells

• NMDA causes an increase in [Ca2+]i in the human brain microvascular endothelial cell line, hCMEC/D3. • NMDARs increase the [Ca2+]i in a flux-independent manner via group 1 mGluRs. • NMDARs may also induce NO release by signaling in a flux-dependent manner. • Endothelial NMDA receptors exploit both...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Negri, Sharon [verfasserIn]

Faris, Pawan

Maniezzi, Claudia

Pellavio, Giorgia

Spaiardi, Paolo

Botta, Laura

Laforenza, Umberto

Biella, Gerardo

Moccia, Dr. Francesco

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2021

Übergeordnetes Werk:

Enthalten in: The phenolic compounds from Dracocephalum moldavica L. - Yang, Li-Na ELSEVIER, 2014, Edinburgh [u.a.]

Übergeordnetes Werk:

volume:99 ; year:2021 ; pages:0

Links:

Volltext

DOI / URN:

10.1016/j.ceca.2021.102454

Katalog-ID:

ELV055610986

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