NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells
• NMDA causes an increase in [Ca2+]i in the human brain microvascular endothelial cell line, hCMEC/D3. • NMDARs increase the [Ca2+]i in a flux-independent manner via group 1 mGluRs. • NMDARs may also induce NO release by signaling in a flux-dependent manner. • Endothelial NMDA receptors exploit both...
Ausführliche Beschreibung
Autor*in: |
Negri, Sharon [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Übergeordnetes Werk: |
Enthalten in: The phenolic compounds from Dracocephalum moldavica L. - Yang, Li-Na ELSEVIER, 2014, Edinburgh [u.a.] |
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Übergeordnetes Werk: |
volume:99 ; year:2021 ; pages:0 |
Links: |
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DOI / URN: |
10.1016/j.ceca.2021.102454 |
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ELV055610986 |
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10.1016/j.ceca.2021.102454 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001555.pica (DE-627)ELV055610986 (ELSEVIER)S0143-4160(21)00108-1 DE-627 ger DE-627 rakwb eng 570 VZ 150 VZ Negri, Sharon verfasserin aut NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • NMDA causes an increase in [Ca2+]i in the human brain microvascular endothelial cell line, hCMEC/D3. • NMDARs increase the [Ca2+]i in a flux-independent manner via group 1 mGluRs. • NMDARs may also induce NO release by signaling in a flux-dependent manner. • Endothelial NMDA receptors exploit both canonical and non-canonical signaling modes. Faris, Pawan oth Maniezzi, Claudia oth Pellavio, Giorgia oth Spaiardi, Paolo oth Botta, Laura oth Laforenza, Umberto oth Biella, Gerardo oth Moccia, Dr. Francesco oth Enthalten in Churchill Livingstone Yang, Li-Na ELSEVIER The phenolic compounds from Dracocephalum moldavica L. 2014 Edinburgh [u.a.] (DE-627)ELV017483441 volume:99 year:2021 pages:0 https://doi.org/10.1016/j.ceca.2021.102454 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U AR 99 2021 0 |
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10.1016/j.ceca.2021.102454 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001555.pica (DE-627)ELV055610986 (ELSEVIER)S0143-4160(21)00108-1 DE-627 ger DE-627 rakwb eng 570 VZ 150 VZ Negri, Sharon verfasserin aut NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • NMDA causes an increase in [Ca2+]i in the human brain microvascular endothelial cell line, hCMEC/D3. • NMDARs increase the [Ca2+]i in a flux-independent manner via group 1 mGluRs. • NMDARs may also induce NO release by signaling in a flux-dependent manner. • Endothelial NMDA receptors exploit both canonical and non-canonical signaling modes. Faris, Pawan oth Maniezzi, Claudia oth Pellavio, Giorgia oth Spaiardi, Paolo oth Botta, Laura oth Laforenza, Umberto oth Biella, Gerardo oth Moccia, Dr. Francesco oth Enthalten in Churchill Livingstone Yang, Li-Na ELSEVIER The phenolic compounds from Dracocephalum moldavica L. 2014 Edinburgh [u.a.] (DE-627)ELV017483441 volume:99 year:2021 pages:0 https://doi.org/10.1016/j.ceca.2021.102454 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U AR 99 2021 0 |
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NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells |
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• NMDA causes an increase in [Ca2+]i in the human brain microvascular endothelial cell line, hCMEC/D3. • NMDARs increase the [Ca2+]i in a flux-independent manner via group 1 mGluRs. • NMDARs may also induce NO release by signaling in a flux-dependent manner. • Endothelial NMDA receptors exploit both canonical and non-canonical signaling modes. |
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• NMDA causes an increase in [Ca2+]i in the human brain microvascular endothelial cell line, hCMEC/D3. • NMDARs increase the [Ca2+]i in a flux-independent manner via group 1 mGluRs. • NMDARs may also induce NO release by signaling in a flux-dependent manner. • Endothelial NMDA receptors exploit both canonical and non-canonical signaling modes. |
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• NMDA causes an increase in [Ca2+]i in the human brain microvascular endothelial cell line, hCMEC/D3. • NMDARs increase the [Ca2+]i in a flux-independent manner via group 1 mGluRs. • NMDARs may also induce NO release by signaling in a flux-dependent manner. • Endothelial NMDA receptors exploit both canonical and non-canonical signaling modes. |
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NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells |
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