FC-BBR/IND-induced glucose oxidase nanodrugs for targeted combination therapy
FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and...
Ausführliche Beschreibung
Autor*in: |
Cheng, Yu [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2022transfer abstract |
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Übergeordnetes Werk: |
Enthalten in: Description d’une cohorte française multicentrique de porteurs asymptomatiques d’anticorps anti-phospholipides - Nigolian, H. ELSEVIER, 2022, New York, NY [u.a.] |
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Übergeordnetes Werk: |
volume:611 ; year:2022 ; day:5 ; month:01 ; pages:0 |
Links: |
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DOI / URN: |
10.1016/j.ijpharm.2021.121349 |
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10.1016/j.ijpharm.2021.121349 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001984.pica (DE-627)ELV056262663 (ELSEVIER)S0378-5173(21)01155-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Cheng, Yu verfasserin aut FC-BBR/IND-induced glucose oxidase nanodrugs for targeted combination therapy 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. Glucose oxidase Elsevier Chemodynamic therapy Elsevier Targeted therapy Elsevier Starvation therapy Elsevier Ferrocene Elsevier Ji, Yuanhui oth Ouyang, Defang oth Enthalten in Elsevier Nigolian, H. ELSEVIER Description d’une cohorte française multicentrique de porteurs asymptomatiques d’anticorps anti-phospholipides 2022 New York, NY [u.a.] (DE-627)ELV008932840 volume:611 year:2022 day:5 month:01 pages:0 https://doi.org/10.1016/j.ijpharm.2021.121349 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.61 Innere Medizin VZ AR 611 2022 5 0105 0 |
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10.1016/j.ijpharm.2021.121349 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001984.pica (DE-627)ELV056262663 (ELSEVIER)S0378-5173(21)01155-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Cheng, Yu verfasserin aut FC-BBR/IND-induced glucose oxidase nanodrugs for targeted combination therapy 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. Glucose oxidase Elsevier Chemodynamic therapy Elsevier Targeted therapy Elsevier Starvation therapy Elsevier Ferrocene Elsevier Ji, Yuanhui oth Ouyang, Defang oth Enthalten in Elsevier Nigolian, H. ELSEVIER Description d’une cohorte française multicentrique de porteurs asymptomatiques d’anticorps anti-phospholipides 2022 New York, NY [u.a.] (DE-627)ELV008932840 volume:611 year:2022 day:5 month:01 pages:0 https://doi.org/10.1016/j.ijpharm.2021.121349 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.61 Innere Medizin VZ AR 611 2022 5 0105 0 |
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10.1016/j.ijpharm.2021.121349 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001984.pica (DE-627)ELV056262663 (ELSEVIER)S0378-5173(21)01155-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Cheng, Yu verfasserin aut FC-BBR/IND-induced glucose oxidase nanodrugs for targeted combination therapy 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. Glucose oxidase Elsevier Chemodynamic therapy Elsevier Targeted therapy Elsevier Starvation therapy Elsevier Ferrocene Elsevier Ji, Yuanhui oth Ouyang, Defang oth Enthalten in Elsevier Nigolian, H. ELSEVIER Description d’une cohorte française multicentrique de porteurs asymptomatiques d’anticorps anti-phospholipides 2022 New York, NY [u.a.] (DE-627)ELV008932840 volume:611 year:2022 day:5 month:01 pages:0 https://doi.org/10.1016/j.ijpharm.2021.121349 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.61 Innere Medizin VZ AR 611 2022 5 0105 0 |
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10.1016/j.ijpharm.2021.121349 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001984.pica (DE-627)ELV056262663 (ELSEVIER)S0378-5173(21)01155-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Cheng, Yu verfasserin aut FC-BBR/IND-induced glucose oxidase nanodrugs for targeted combination therapy 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. Glucose oxidase Elsevier Chemodynamic therapy Elsevier Targeted therapy Elsevier Starvation therapy Elsevier Ferrocene Elsevier Ji, Yuanhui oth Ouyang, Defang oth Enthalten in Elsevier Nigolian, H. ELSEVIER Description d’une cohorte française multicentrique de porteurs asymptomatiques d’anticorps anti-phospholipides 2022 New York, NY [u.a.] (DE-627)ELV008932840 volume:611 year:2022 day:5 month:01 pages:0 https://doi.org/10.1016/j.ijpharm.2021.121349 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.61 Innere Medizin VZ AR 611 2022 5 0105 0 |
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10.1016/j.ijpharm.2021.121349 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001984.pica (DE-627)ELV056262663 (ELSEVIER)S0378-5173(21)01155-8 DE-627 ger DE-627 rakwb eng 610 VZ 44.61 bkl Cheng, Yu verfasserin aut FC-BBR/IND-induced glucose oxidase nanodrugs for targeted combination therapy 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. Glucose oxidase Elsevier Chemodynamic therapy Elsevier Targeted therapy Elsevier Starvation therapy Elsevier Ferrocene Elsevier Ji, Yuanhui oth Ouyang, Defang oth Enthalten in Elsevier Nigolian, H. ELSEVIER Description d’une cohorte française multicentrique de porteurs asymptomatiques d’anticorps anti-phospholipides 2022 New York, NY [u.a.] (DE-627)ELV008932840 volume:611 year:2022 day:5 month:01 pages:0 https://doi.org/10.1016/j.ijpharm.2021.121349 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.61 Innere Medizin VZ AR 611 2022 5 0105 0 |
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FC-BBR/IND-induced glucose oxidase nanodrugs for targeted combination therapy |
abstract |
FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. |
abstractGer |
FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. |
abstract_unstemmed |
FC-BBR and IND induced glucose oxidase (GOD) to self-assemble, which was then encapsulated by HA to form nanodrugs (FC-BBR/INDGOD@HA NPs). The prepared nanoassembly could inhibit the proliferation and induce the apoptosis of HepG2 cells, which might be the result of targeted chemodynamic therapy and starvation therapy mediated by HA and BBR. Moreover, the FC-BBR/IND@GOD@HA NPs could also reduce the mitochondrial membrane potential, increase the level of reactive oxygen species and block cells in S phase. More importantly, it could inhibit the movement and migration of cancer cells, which gave it the potential to prevent tumor metastasis. |
collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U |
title_short |
FC-BBR/IND-induced glucose oxidase nanodrugs for targeted combination therapy |
url |
https://doi.org/10.1016/j.ijpharm.2021.121349 |
remote_bool |
true |
author2 |
Ji, Yuanhui Ouyang, Defang |
author2Str |
Ji, Yuanhui Ouyang, Defang |
ppnlink |
ELV008932840 |
mediatype_str_mv |
z |
isOA_txt |
false |
hochschulschrift_bool |
false |
author2_role |
oth oth |
doi_str |
10.1016/j.ijpharm.2021.121349 |
up_date |
2024-07-06T19:53:24.901Z |
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1803860684205719552 |
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7.400448 |