Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic
Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated usin...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Queiroz, Priscilla Mol [verfasserIn] Barrioni, Breno Rocha [verfasserIn] Valverde, Thalita Marcolan [verfasserIn] de Goes, Alfredo Miranda [verfasserIn] Gomes, Dawidson Assis [verfasserIn] Pereira, Marivalda de Magalhães [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Journal of non-crystalline solids - Amsterdam [u.a.] : Elsevier Science, 1968, 622 |
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| Übergeordnetes Werk: |
volume:622 |
| DOI / URN: |
10.1016/j.jnoncrysol.2023.122656 |
|---|
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ELV065337913 |
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| 520 | |a Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. | ||
| 650 | 4 | |a Mesoporous | |
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| 700 | 1 | |a Barrioni, Breno Rocha |e verfasserin |4 aut | |
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| 700 | 1 | |a de Goes, Alfredo Miranda |e verfasserin |4 aut | |
| 700 | 1 | |a Gomes, Dawidson Assis |e verfasserin |4 aut | |
| 700 | 1 | |a Pereira, Marivalda de Magalhães |e verfasserin |4 aut | |
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10.1016/j.jnoncrysol.2023.122656 doi (DE-627)ELV065337913 (ELSEVIER)S0022-3093(23)00521-5 DE-627 ger DE-627 rda eng 660 670 VZ 51.45 bkl 51.60 bkl 33.61 bkl 35.90 bkl Queiroz, Priscilla Mol verfasserin (orcid)0000-0002-6667-9867 aut Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. Mesoporous Bioactive glasses Nanoparticles Manganese Post-synthesis impregnation Barrioni, Breno Rocha verfasserin aut Valverde, Thalita Marcolan verfasserin aut de Goes, Alfredo Miranda verfasserin aut Gomes, Dawidson Assis verfasserin aut Pereira, Marivalda de Magalhães verfasserin aut Enthalten in Journal of non-crystalline solids Amsterdam [u.a.] : Elsevier Science, 1968 622 Online-Ressource (DE-627)306659808 (DE-600)1500501-X (DE-576)096806486 0022-3093 nnns volume:622 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 51.45 Werkstoffe mit besonderen Eigenschaften VZ 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 33.61 Festkörperphysik VZ 35.90 Festkörperchemie VZ AR 622 |
| spelling |
10.1016/j.jnoncrysol.2023.122656 doi (DE-627)ELV065337913 (ELSEVIER)S0022-3093(23)00521-5 DE-627 ger DE-627 rda eng 660 670 VZ 51.45 bkl 51.60 bkl 33.61 bkl 35.90 bkl Queiroz, Priscilla Mol verfasserin (orcid)0000-0002-6667-9867 aut Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. Mesoporous Bioactive glasses Nanoparticles Manganese Post-synthesis impregnation Barrioni, Breno Rocha verfasserin aut Valverde, Thalita Marcolan verfasserin aut de Goes, Alfredo Miranda verfasserin aut Gomes, Dawidson Assis verfasserin aut Pereira, Marivalda de Magalhães verfasserin aut Enthalten in Journal of non-crystalline solids Amsterdam [u.a.] : Elsevier Science, 1968 622 Online-Ressource (DE-627)306659808 (DE-600)1500501-X (DE-576)096806486 0022-3093 nnns volume:622 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 51.45 Werkstoffe mit besonderen Eigenschaften VZ 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 33.61 Festkörperphysik VZ 35.90 Festkörperchemie VZ AR 622 |
| allfields_unstemmed |
10.1016/j.jnoncrysol.2023.122656 doi (DE-627)ELV065337913 (ELSEVIER)S0022-3093(23)00521-5 DE-627 ger DE-627 rda eng 660 670 VZ 51.45 bkl 51.60 bkl 33.61 bkl 35.90 bkl Queiroz, Priscilla Mol verfasserin (orcid)0000-0002-6667-9867 aut Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. Mesoporous Bioactive glasses Nanoparticles Manganese Post-synthesis impregnation Barrioni, Breno Rocha verfasserin aut Valverde, Thalita Marcolan verfasserin aut de Goes, Alfredo Miranda verfasserin aut Gomes, Dawidson Assis verfasserin aut Pereira, Marivalda de Magalhães verfasserin aut Enthalten in Journal of non-crystalline solids Amsterdam [u.a.] : Elsevier Science, 1968 622 Online-Ressource (DE-627)306659808 (DE-600)1500501-X (DE-576)096806486 0022-3093 nnns volume:622 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 51.45 Werkstoffe mit besonderen Eigenschaften VZ 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 33.61 Festkörperphysik VZ 35.90 Festkörperchemie VZ AR 622 |
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10.1016/j.jnoncrysol.2023.122656 doi (DE-627)ELV065337913 (ELSEVIER)S0022-3093(23)00521-5 DE-627 ger DE-627 rda eng 660 670 VZ 51.45 bkl 51.60 bkl 33.61 bkl 35.90 bkl Queiroz, Priscilla Mol verfasserin (orcid)0000-0002-6667-9867 aut Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. Mesoporous Bioactive glasses Nanoparticles Manganese Post-synthesis impregnation Barrioni, Breno Rocha verfasserin aut Valverde, Thalita Marcolan verfasserin aut de Goes, Alfredo Miranda verfasserin aut Gomes, Dawidson Assis verfasserin aut Pereira, Marivalda de Magalhães verfasserin aut Enthalten in Journal of non-crystalline solids Amsterdam [u.a.] : Elsevier Science, 1968 622 Online-Ressource (DE-627)306659808 (DE-600)1500501-X (DE-576)096806486 0022-3093 nnns volume:622 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 51.45 Werkstoffe mit besonderen Eigenschaften VZ 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 33.61 Festkörperphysik VZ 35.90 Festkörperchemie VZ AR 622 |
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10.1016/j.jnoncrysol.2023.122656 doi (DE-627)ELV065337913 (ELSEVIER)S0022-3093(23)00521-5 DE-627 ger DE-627 rda eng 660 670 VZ 51.45 bkl 51.60 bkl 33.61 bkl 35.90 bkl Queiroz, Priscilla Mol verfasserin (orcid)0000-0002-6667-9867 aut Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. Mesoporous Bioactive glasses Nanoparticles Manganese Post-synthesis impregnation Barrioni, Breno Rocha verfasserin aut Valverde, Thalita Marcolan verfasserin aut de Goes, Alfredo Miranda verfasserin aut Gomes, Dawidson Assis verfasserin aut Pereira, Marivalda de Magalhães verfasserin aut Enthalten in Journal of non-crystalline solids Amsterdam [u.a.] : Elsevier Science, 1968 622 Online-Ressource (DE-627)306659808 (DE-600)1500501-X (DE-576)096806486 0022-3093 nnns volume:622 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 51.45 Werkstoffe mit besonderen Eigenschaften VZ 51.60 Keramische Werkstoffe Hartstoffe Werkstoffkunde VZ 33.61 Festkörperphysik VZ 35.90 Festkörperchemie VZ AR 622 |
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Enthalten in Journal of non-crystalline solids 622 volume:622 |
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Enthalten in Journal of non-crystalline solids 622 volume:622 |
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Werkstoffe mit besonderen Eigenschaften Keramische Werkstoffe Hartstoffe Festkörperphysik Festkörperchemie |
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findex.gbv.de |
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Mesoporous Bioactive glasses Nanoparticles Manganese Post-synthesis impregnation |
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Journal of non-crystalline solids |
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Queiroz, Priscilla Mol @@aut@@ Barrioni, Breno Rocha @@aut@@ Valverde, Thalita Marcolan @@aut@@ de Goes, Alfredo Miranda @@aut@@ Gomes, Dawidson Assis @@aut@@ Pereira, Marivalda de Magalhães @@aut@@ |
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2023-01-01T00:00:00Z |
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Queiroz, Priscilla Mol |
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Queiroz, Priscilla Mol ddc 660 bkl 51.45 bkl 51.60 bkl 33.61 bkl 35.90 misc Mesoporous misc Bioactive glasses misc Nanoparticles misc Manganese misc Post-synthesis impregnation Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic |
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660 670 VZ 51.45 bkl 51.60 bkl 33.61 bkl 35.90 bkl Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic Mesoporous Bioactive glasses Nanoparticles Manganese Post-synthesis impregnation |
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Queiroz, Priscilla Mol Barrioni, Breno Rocha Valverde, Thalita Marcolan de Goes, Alfredo Miranda Gomes, Dawidson Assis Pereira, Marivalda de Magalhães |
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study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic |
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Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic |
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Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. |
| abstractGer |
Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. |
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Mesoporous bioactive glasses nanoparticles (MBGNPs) have shown great potential for tissue regeneration, and therapeutic ions incorporation into the glass system is a potential strategy to improve its performance. Here, manganese ions, known to favor osteogenic differentiation, were incorporated using a post-synthesis impregnation method, and the Mn influence into the SiO2-CaO structure and properties were evaluated. Morphological analysis confirmed that spherical mesoporous BGNPs with up to 67 ± 24 nm were obtained, and x-ray photoelectron spectroscopy showed that Mn could be incorporated into the glass as a network modifier or deposited as a manganese oxide crystalline phase, forming a bioactive glass-ceramic material. A cell-friendly environment and osteogenic potential was observed in cellular assays, with a manganese dose-dependent effect on cell viability and alkaline phosphatase activity. Thus, results indicate that Mn-releasing MBGNPs could be obtained through the post-synthesis impregnation method and are promising candidates for bone repair. |
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Study of the manganese and calcium synergetic influence on mesoporous bioactive glass characteristic |
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| score |
7.403059 |